LOS ANGELES--(BUSINESS WIRE)--Puma Biotechnology, Inc. (Nasdaq: PBYI), a biopharmaceutical company, announced the presentation of positive results from an ongoing Phase II clinical trial (Translational Breast Cancer Research Consortium TBCRC 022) of Puma's investigational drug PB272 (neratinib) for the treatment of HER2-positive metastatic breast cancer that has metastasized to the brain. The data were presented today in an oral presentation at the American Society of Clinical Oncology (ASCO) 2017 Annual Meeting in Chicago, Illinois. The multicenter Phase II clinical trial enrolled patients with HER2-positive metastatic breast cancer who have brain metastases. The trial is being performed by the TBCRC and enrolled three cohorts of patients. Patients in the first cohort (n=40) included those with progressive brain metastases who were administered neratinib monotherapy. Data from this cohort were previously reported at the 2014 ASCO Annual Meeting and published in the Journal of Clinical Oncology in 2016. Patients in the second cohort (n=5) represent patients who had brain metastases which were amenable to surgery and who were administered neratinib monotherapy prior to and after surgical resection. The third cohort (target enrollment=60) enrolled two sub-groups of patients (prior lapatinib-treated and no prior lapatinib) with progressive brain metastases who were administered neratinib in combination with … Continue reading →

If you are interested in a career in one of the most interesting areas of science then you should consider joining the field of biotechnology. Armed with a BSc Biotechnology degree, you will be able to apply for many interesting and high paying jobs across a number of industries. As a matter of fact, there are quite a few colleges in Dehradun that offer three year graduate programs in biotechnology because there is a great deal of demand for a degree in this field on account of its robust job prospects. Keep in mind that youll generally need to have a background in science (10 + 2) in order to be able to apply for this course because math, biology and chemistry are very important to students in this field. The field of biotechnology is growing at a very rapid pace and it is also essential to many industries. The importance of this field comes from its ability to use technological methodologies to improve a number of biological systems in order to create new processes and products that have the ability to improve our life overall. The field of biotechnology consists of many different areas of study. Some of the … Continue reading →

There are plenty of explanations of what biotechnology is, but the simplest one is that it is a field of study where biology is the foundation on which different kinds of technology are developed. Biotechnology is the basis of many different kinds of research in the fields of environment, food science, robotics, agriculture and medicine. The human involvement in manipulating their environment is now at remarkable levels. From the most basic direct organism manipulations such as fermenting beer and culturing bacteria to advanced nucleotide-based organ regeneration and animal cloning, our knowledge and technology has advanced far beyond what anyone wouldve expected just a decade ago. But even before there was a name to call it by, biotechnology was in existence. Even something that people have been doing for centuries, like preservatives to keep food edible during winter, is a form of biotechnology. When around 6000 BC, fruit juice was first fermented to form alcohol, it was another instance of biotechnology. Of course, it has emerged as a science only recently. About twenty years ago, the role of genetics in artificially creating proteins in a living being was discovered. DNA was discovered and molecular biology became a part of mainstream science. … Continue reading →