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Mother Makes Ultimate Sacrifice for Unborn Child on ABC's 'Grey's Anatomy' – NewsBusters (blog)

Posted: Published on April 29th, 2017

NewsBusters (blog) Mother Makes Ultimate Sacrifice for Unborn Child on ABC's 'Grey's Anatomy' NewsBusters (blog) But in April 27th's episode of Grey's Anatomy on ABC, we got to see that rarity played out in a heart-wrenching yet inspiring storyline. Patient Veronica is in the ER at Grey-Sloan Memorial Hospital for back pain. She's almost 35 weeks pregnant and her ... Visit link: Mother Makes Ultimate Sacrifice for Unborn Child on ABC's 'Grey's Anatomy' - NewsBusters (blog) … Continue reading →

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'Big Bang Theory,' 'Grey's Anatomy' and 'Masterchef Junior' adjust up; 'The Catch' adjusts down: Thursday final ratings – TVbytheNumbers

Posted: Published on April 29th, 2017

TVbytheNumbers 'Big Bang Theory,' 'Grey's Anatomy' and 'Masterchef Junior' adjust up; 'The Catch' adjusts down: Thursday final ratings TVbytheNumbers The Big Bang Theory avoided a new series low among adults 18-49 and finished ahead of its last episode by adjusting up from Thursday's early ratings to the finals. The show's 18-49 rating came up two tenths of a point to 2.6, 0.1 higher than ... 'Big Bang Theory' & 'Grey's Anatomy' Rise In Adjusted Ratings, 'The Catch' Down UpdateDeadline all 8 news articles » Link: 'Big Bang Theory,' 'Grey's Anatomy' and 'Masterchef Junior' adjust up; 'The Catch' adjusts down: Thursday final ratings - TVbytheNumbers … Continue reading →

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Cell-based Therapy Shows Promise in Treating Duchenne Muscular … – Bioscience Technology

Posted: Published on April 28th, 2017

Clinical-stage biotech company Capricor Therapeutics Inc., has announced positive six-month results from a randomized 12-month Phase 1/2 trial in patients with Duchenne muscular dystrophy (DMD), which was designed to analyze safety and exploratory efficacy. DMD is a rare, genetic disorder that often occurs in boys. It involves progressive muscular weakness and patients often experience frequent falls, have trouble getting up, or performing daily tasks such as eating, as well as learning disabilities, and treatment options are limited. Cardiac disease is the most common cause of death among those with DMD, who often dont survive past their twenties, and early results from the trial showed statistically significant improvements in measures of cardiac and upper limb function in patients treated with the cell-based therapy called CAP-1002. CAP-1002 is comprised of allogeneic cardiosphere-derived cells, or CDCs, which are a type of progenitor cell. The HOPE trial, involved 25 patients, aged 12 years an older, with DMD who had cardiomyopathy, or heart disease secondary to DMD. Thirteen patients were randomized to receive a single dose of CAP-1002, while 12 received usual care. The cell therapy was infused into the three main coronary arties, with a total dose of 75 million cells. MRI assessments showed … Continue reading →

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Sarepta hikes forecast for Duchenne muscular dystrophy drug sales … – Boston Business Journal

Posted: Published on April 28th, 2017

Boston Business Journal Sarepta hikes forecast for Duchenne muscular dystrophy drug sales ... Boston Business Journal Sarepta Therapeutics CEO Ed Kaye said Thursday that he plans to step down from his post at the Cambridge biotech at the end of the year. Kaye, who was ... and more » Continue reading here: Sarepta hikes forecast for Duchenne muscular dystrophy drug sales ... - Boston Business Journal … Continue reading →

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Duchenne muscular dystrophy: Push for Australian trials of homegrown drug – ABC Online

Posted: Published on April 28th, 2017

Posted April 26, 2017 19:43:27 A US teenager who can walk because of a drug created in WA has joined a campaign for human trials to be run in Australia. Two researchers from Perth's Murdoch University created the drug that has kept 16-year-old Billy Ellsworth, from Pennsylvania, on his feet but the drug is not yet available to Australian families. Billy has Duchenne muscular dystrophy, a rare and fatal genetic disease, which eventually wastes every muscle in the body. It affects one in 3,500 children, mostly boys, and leaves most wheelchair bound by the age of 12. Many people with the condition do not live past 25. "It's good, it feels good to be walking for this long and I'm glad I can," Billy said. The teenager has been one of 12 boys in the United States on a six-year trial of Exondys 51, a drug created by two researchers in WA. The drug targets a specific group of gene mutations which causes the fatal disease rendering it effective in slowing down muscle wasting in about 10 per cent of people with the condition. Terri Ellsworth said what it had done for her son had left her, at times, speechless. … Continue reading →

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Amber Alert: Boy, 4, taken from Lady Cilento Children’s Hospital – NEWS.com.au

Posted: Published on April 28th, 2017

Anti-vaxxer mum Cini Walker describes her son Chase Walker-Steven's health challenges. Jacinda Walker and Marc Steven with son Chase Walker-Steven. The couple are on the run with the four-year-old. A SEVERELY disabled four-year-old boy taken from a Brisbane childrens hospital by his desperate parents has been found safe and well. Chase Walker-Stevens mother was found in Newcastle on Friday, after a tip-off from a member of the public when Queensland Police issued an urgent amber alert. She then led police to the location of the boy and his father. No charges are likely be laid against the pair, Acting Detective Inspector Grant Ralston said. The most important thing for us was that he was found and taken to hospital, he said. Det Insp Ralston said the boys parents had co-operated with police and he was en route to hospital. Queensland Police issued the amber alert to find the four-year-old, after his anti-vaxxer parents took the wheelchair-bound child from Brisbanes Lady Cilento Childrens Hospital on Thursday, when he was hospitalised against their wishes. Jacinda Walker and Marc Steven with son Chase Walker-Steven and their daughter.Source:Supplied Det Insp Ralston said a member of the public tipped police off, after sighting the boys … Continue reading →

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17 Year Old Teen Scientist’s Game-changing Research on Treatment for Brain Damage – FactsChronicle

Posted: Published on April 28th, 2017

The Regeneron Science Talent Search (Regeneron STS) is the USAs most prestigious pre-college science competition. Alumni of STS have made extraordinary contributions to science and hold more than 100 of the worlds most coveted science and math honors, including the Nobel Prize and National Medal of Science. It brings to the fore many new types of research in science and many brilliant minds who are contributing to our society and solving age-old problems related to science, health, math, and the likes. One such brilliant mind, participating in the Regeneron STS this year, is Indrani Das a 17-year-old high schooler whose research will change many peoples lives. She has won the top prize in the talent search. Das has developed a treatment that keeps neurons from dying after a brain injury. Brain tissue is composed of neurons and other supporting cells, such as glia. Neurons in the brain are interconnected to make functional circuits. If these connections are interrupted as a result of trauma, brain function is impaired. Neurons are post-mitotic and therefore cannot divide to produce new neurons making a neuronal loss as a result of trauma profoundly detrimental to normal brain function. It is irreversible and presently there is … Continue reading →

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5 Stem Cell Innovations From The Past Year, From Cancer Treatment To Diabetes Therapy – Medical Daily

Posted: Published on April 28th, 2017

Ten years ago, the topic of stem cells was shrouded in mystery, but now they're at the forefront of some of the latest innovations in biologyand medicine. Stem cellshave yet to change into a specific type of cell, such as a brain or skin cell. As a result, doctors can manipulate them into, well, any type of cellthey want. However, the way that stem cells are being manipulated is anything but simple. Here is a run-downof fiveof the most fascinating stem cell innovations fromthe past year. Teeth are necessary for helping uschew our food, but once they fall out. they're useless; or not? The practice of tooth saving, or cryopreserving, has gained popularity, and forgood reason. New research suggests the stem cells found in the pulp of teeth could be used to help people regrow their adult teeth (rather than needing a crown or dentures), and may even have other potentially life-saving regenerative medical benefits, CNN reported. While still in its early stages, the idea behind tooth preservation is that no other stem cells work better than your own. By saving your baby teeth, oradult teeth that need to be removed through surgery, you may later harvest stem cells that … Continue reading →

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$10 million settlement over alleged misconduct in Boston heart stem cell lab – Science Magazine

Posted: Published on April 28th, 2017

Brigham and Women's Hospital in Boston. BRIAN SNYDER/REUTERS/Newscom By Kelly ServickApr. 27, 2017 , 5:00 PM A research misconduct investigation of a prominent stem cell lab by the Harvard Universityaffiliated Brigham and Womens Hospital (BWH) in Boston has led to a massive settlement with the U.S. government over allegations of fraudulently obtained federal grants. As Retraction Watch reports, BWH and its parent health care system have agreed to pay $10 million to resolve allegations that former BWH cardiac stem cell scientist Piero Anversa and former lab members Annarosa Leri and Jan Kajstura relied on manipulated and fabricated data in grant applications submitted to the U.S. National Institutes of Health (NIH). A statement from the U.S. Attorneys Office for the District of Massachusetts released today notes that it was BWH itself that shared the allegations against Anversas lab with the government. The hospital had been conducting its own probe into the Anversa lab since at least 2014, when a retraction published in the journal Circulation revealed the ongoing investigation. The hospital has not yet released any findings. In 2014, Anversa and Leri sued Harvard and BWHalong with BWH President Elizabeth Nabel and Gretchen Brodnicki, Harvards dean for faculty and research integrityfor … Continue reading →

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Transparent Bones Enable Researchers to Observe Stem Cells Inside – Laboratory Equipment

Posted: Published on April 28th, 2017

Ten years ago, the bones currently in your body did not actually exist. Like skin, bone is constantly renewing itself, shedding old tissue and growing it anew from stem cells in the bone marrow. Now, a new technique developed at Caltech can render intact bones transparent, allowing researchers to observe these stem cells within their environment. The method is a breakthrough for testing new drugs to combat diseases like osteoporosis. The research was done in the laboratory of Viviana Gradinaru (BS '05), assistant professor of biology and biological engineering and a Heritage Medical Research Institute Investigator. It appears in a paper in the April 26 issue of Science Translational Medicine. In healthy bone, a delicate balance exists between the cells that build bone mass and the cells that break down old bone in a continual remodeling cycle. This process is partially controlled by stem cells in bone marrow, called osteoprogenitors, that develop into osteoblasts or osteocytes, which regulate and maintain the skeleton. To better understand diseases like osteoporosis, which occurs when loss of bone mass leads to a high risk of fractures, it is crucial to study the behavior of stem cells in bone marrow. However, this population is rare … Continue reading →

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