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A New Form of Stem-Cell Engineering Raises Ethical Questions – New York Times

Posted: Published on March 21st, 2017

New York Times A New Form of Stem-Cell Engineering Raises Ethical Questions New York Times A scan of the surface of a human embryonic stem cell. Credit David Scharf/Science Source. As biological research races forward, ethical quandaries are piling up. In a report published Tuesday in the journal eLife, researchers at Harvard Medical School ... Harvard Scientists Call For Better Rules To Guide Research On 'Embryoids'WXXI News all 4 news articles » Excerpt from: A New Form of Stem-Cell Engineering Raises Ethical Questions - New York Times … Continue reading

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Synthego Announces Modified Synthetic sgRNA — Critical for Editing Primary and Stem Cells, and other Challenging … – Yahoo Finance

Posted: Published on March 21st, 2017

REDWOOD CITY, CA--(Marketwired - Mar 21, 2017) - Synthego, a leading provider of genome engineering solutions, today announces the availability of chemically modified synthetic guide RNA in the CRISPRevolution product family, including modified full length 100-mer synthetic single guide RNA (sgRNA). Critical for editing challenging cell types such as primary and stem cells, modified guide RNAs provide protection against intracellular immune responses present in primary cells, such as stem cells. Additionally, chemically modified RNA improves in vivo stability by protecting RNA molecules against exonuclease attack -- allowing it to persist longer in certain cell types and regions of genomic DNA that can be challenging to edit using conventional guide RNAs. Synthego's modified sgRNA are synthesized with 2'-O-methyl analogs and 3' phosphorothioate internucleotide linkages in the first three nucleotides at both the 5' and 3' end of the RNA molecule. It's currently impossible to make chemical modifications to plasmid or in vitro transcription (IVT) based guide RNAs. Synthetic sgRNA is chemically synthesized to the highest levels of purity, eliminating the risk of introducing toxins that may be present in IVT-based guide RNAs. In addition, the use of modified synthetic sgRNA also safeguards against the accidental incorporation of DNA into edited stem … Continue reading

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New research shows promise for the production of patient-matched blood cells for therapies, disease modeling and … – Science Daily

Posted: Published on March 21st, 2017

New research shows promise for the production of patient-matched blood cells for therapies, disease modeling and ... Science Daily The Galat laboratory at Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, has developed an elegant system to derive blood cell precursors from human pluripotent stem cells (hPSC). This type of stem cell ... and more » See original here: New research shows promise for the production of patient-matched blood cells for therapies, disease modeling and ... - Science Daily … Continue reading

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Unproven stem cell ‘therapy’ blinds three patients at Florida clinic … – Science Daily

Posted: Published on March 21st, 2017

Science Daily Unproven stem cell 'therapy' blinds three patients at Florida clinic ... Science Daily Three people with macular degeneration were blinded after undergoing an unproven stem cell treatment that was touted as a clinical trial in 2015 at a clinic in ... Strategy shift: Stem cell research uses donor cells to cut tumor risksGenetic Literacy Project Experimental stem cell treatment leaves 3 women blindThe Whittier Daily News Unproven stem cell 'therapy' blinds three patients at Florida clinicStanford Report all 46 news articles » See the original post here: Unproven stem cell 'therapy' blinds three patients at Florida clinic ... - Science Daily … Continue reading

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Okyanos Cell Therapy Brings Stem Cell Education to North Florida – PR Web (press release)

Posted: Published on March 21st, 2017

Tapestry Senior Living is Tallahasee's newest senior living and memory care facility, located at 2516 West Lakeshore Drive, Tallahassee, FL 32312. Freeport, Grand Bahama (PRWEB) March 21, 2017 Okyanos Cell Therapy has announced Tallahassee, FL will be the next destination for a free educational seminar as part of their live events series, Stem Cell Therapy: The Next Phase in the Evolution of Medicine. As the Bahamas first fully licensed adult stem cell facility under the 2013 Stem Cell Research and Therapy Act, Okyanos maintains a mission to help no-option patients and those with serious, progressive conditions to return to a more normal life utilizing cell therapy. The Tallahasee event will take place at Tapestry Senior Living on Saturday, April 8, 2017 at 10:00am. Pre-registration is required. If you wish to attend or learn more, please email seminars(at)okyanos(dot)com. With stem cells existing as somewhat of a buzzword in healthcare today, questions loom as to what the true potential of stem cell-based therapies is for conditions like Parkinsons Disease, osteoarthritis and heart failure. It is through their free live education series that Okyanos works to raise awareness and bring understanding on the potential of stem cell research and treatment, as well as … Continue reading

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Chemistry 101 – What Is Chemistry? – thoughtco.com

Posted: Published on March 20th, 2017

What Is Chemistry? Chemistry is the study of matter and energy and the interactions between them. This is also the definition for physics, by the way. Chemistry and physics are specializations of physical science. Chemistry tends to focus on the properties of substances and the interactions between different types of matter, particularly reactions that involve electrons. Physics tends to focus more on the nuclear part of the atom, as well as the subatomic realm. Really, they are two sides of the same coin. The formal definition of chemistry is probably what you want to use if you're asked this question on a test. Because understanding chemistry helps you to understand the world around you. Cooking is chemistry. Everything you can touch or taste or smell is a chemical. When you study chemistry, you come to understand a bit about how things work. Chemistry isn't secret knowledge, useless to anyone but a scientist. It's the explanation for everyday things, like why laundry detergent works better in hot water or how baking soda works or why not all pain relievers work equally well on a headache. If you know some chemistry, you can make educated choices about everyday products that you use. … Continue reading

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Kristaps Porzingis, Derrick Rose see lack of Knicks’ chemistry – Newsday

Posted: Published on March 20th, 2017

SANTA MONICA, Calif. Kristaps Porzingis was the first to see something and say something when he expressed that despite the Knicks early-season success, something was missing. The second-year big man proved to have great foresight. I think it was pretty easy to tell from the inside that were not that good of a team, Porzingis said after Sundays practice. We can win games based off of our talent, but thats not going to last long, and thats exactly what happened. Porzingis said he felt that way when the Knicks were 14-10, but he never thought it would turn out as bad as it has. Since then, they have gone 13-32. Theyve clinched a fourth straight losing season and, according to Derrick Rose, need a miracle to make the playoffs. The Knicks are 6 12 games behind the Eastern Conferences last playoff spot with 13 to play. Theyre closer to getting a higher draft pick than making the playoffs. We all expected big things out of this year, said Porzingis, who should return Monday night against the Clippers after missing the previous game with a bruised left thigh. . . . I felt like we would make good runs but we … Continue reading

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Taking on chemistry’s reproducibility problem – Chemistry World (subscription)

Posted: Published on March 20th, 2017

Not a week passes without reproducibility in science or the lack of it hitting the headlines. Although much of the criticism is directed at the biomedical sciences or psychology, many of the same problems also pervade the chemical sciences. A survey of over 1500 scientists conducted by Nature last year revealed that 70% of researchers think that science faces a reproducibility crisis. Over half, however, still have faith in published literature in their field with chemists being amongst the most confident despite reporting the most difficulty replicating other researchers or their own work. Although this observation seems contradictory, an explanation might be that chemists are more often looking to repeat experiments exactly, says Rick Danheiser, a synthetic organic chemist at the Massachusetts Institute of Technology. Chemical journal articles suffer from the inability of people to name compounds accurately Anita Bandrowski, University of California, San Diego Danheiser is the editor-in-chief of the unconventional journal Organic Syntheses that has verified the experiments of all the papers it has published since it launched in 1921. The journal does this by having the research replicated by independent chemists before publishing them a practice that is almost unheard of in chemistry or any other research … Continue reading

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New database highlights cumulative chemical dangers – Chemistry World (subscription)

Posted: Published on March 20th, 2017

A collaborative and publicly available database of previously inaccessible hazardous chemical reactions has been launched by the Pistoia Alliance, a not for profit group based in Boston, US. This new Chemical Safety Library (CSL) service features a submission tool that allows researchers to add safety data in just minutes, helping to prevent dangerous events from being repeated. The system was designed in conjunction with Pistoias industry members, including Bristol-Myers Squibb, AstraZeneca and Pfizer. Although many commercial and open resources already offer information on the hazardous properties of individual reagents, often there are no details about the effect of combining such reagents, according to Steve Arlington, the Pistoia Alliances president. In addition, such events are often not shared within or between companies. The CSLs chemical reaction incident dataset can be downloaded, and it can also be configured to alert scientists if there is a known safety risk before they carry out a research project. Within hours of Pistoia announcing the CSL on 16 March, 150 people had already signed up to use the new system, says Carmen Nitsche, a business development consultant for Pistoia. Users have access to the base set of about 25 incidents with which Pistoia pre-populated the system, … Continue reading

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Chemistry And Beyond: Three Keys To A Successful CMO-Branding Agency Relationship – Forbes

Posted: Published on March 20th, 2017

Forbes Chemistry And Beyond: Three Keys To A Successful CMO-Branding Agency Relationship Forbes Many factors contribute to a successful rebrand solid research, stellar creativity, a strategic launch plan and more. But here's one critical factor that's often overlooked: the relationship between the branding firm and the CMO. A productive ... See original here: Chemistry And Beyond: Three Keys To A Successful CMO-Branding Agency Relationship - Forbes … Continue reading

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