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Retinitis Pigmentosa Overview, Risk Factors, Signs …

Posted: Published on August 12th, 2015

Overview of Retinitis Pigmentosa Retinitis pigmentosa is a term that refers to group of hereditary disorders that affect the retina's ability to respond to light. The condition primarily affects rod cellsthe photoreceptor cells that are responsible for night vision, seeing in dim light, and peripheral vision. Cone cells, which are responsible for color vision and seeing in bright light, may also be affected as the disease progresses. Retinitis pigmentosa may be caused by mutations in any one of at least ten different genes, resulting in a malfunction in the retinal pigment epithelial (RPE) cells and a breakdown of a portion of the outer segment disc membrane of photoreceptor cells. When cells are destroyed at an abnormal rate, the build-up of waste products interferes with normal retinal function. The result is the occlusion (blockage) of small blood vessels, an abnormal increase in the number of RPE cells (hyperplasia), and the loss of photoreceptor cells. Retinitis pigmentosa is relatively rare. It affects 50,000 to 100,000 people in the United States. Worldwide, approximately 1.5 million people are afflicted. Retinitis pigmentosa is caused by a genetic defect. Patterns may be of three types: Ocular signs start with the breakdown of rod cells. Rods are … Continue reading →

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Toronto Cosmetic Plastic Surgery Centre and Medical Spa …

Posted: Published on August 12th, 2015

Welcome to SpaMedica Infinite Vitality Clinic, one of Canadas most reputable and trusted names in the field of aesthetic medicine. If youd like to learn more about the industry-leading treatments offered at our clinics, you can do so by choosing one of the three options above. If you are visiting us because you have a cosmetic concern and would like more information on the solutions available, then select the area of your concern below, and we will guide you with some of the most comprehensive information available on the web. Thank you for trusting SpaMedica. While putting your best face forward is a clichd saying, its still an important thought anyway. Your face is what shows your emotions and expressions. People focus on your face in social, work and day-to-day situations every day. Your happiness, sadness, anger and excitement shows from your facial features. You want to look how you feel inside. You dont want to look tired or angry when youre not. Or perhaps youre ready to take years off your looks because natural ageing has worn you down. At SpaMedica, Dr. Mulholland offers several surgical and non-surgical options to rejuvenate your face. Dermal fillers and Botox injections quickly … Continue reading →

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Cardiology – CIMS Hospital, Ahmedabad – Leading Multi …

Posted: Published on August 11th, 2015

August 6, 2015August 6, 2015 June 5, 2015June 5, 2015 May 22, 2015May 22, 2015 A recent milestone achieved by CIMS Cancer Center in Radiotherapy is the AERB approval to use FFF (Flattening Filter- Free) for clinical use. By removing the flattening filter from the linear accelerator, greater dose rate can be achieved due to the physiologic property of flat beam. Advanced treatment like SRS (Stereotactic Radio Surgery) SRT (Stereotactic Radio Therapy) and SBRT (Stereotactic Body Radiation Therapy for Lungs and Prostate) with use of state of art planning system can now be used to modulate non-flat, high dose rate beams to achieve highly conformal dose distributions with a reduced treatment time. April 10, 2015April 10, 2015 At CIMS hospital Ahmedabad a breakthrough technological surgery was performed for the first time in India on an 82 year old gentleman who had stenosis of one of the valve with heart failure, bad lungs , multiple blocks in the peripheral arteries and mild kidney disease . He had a past history of 2 times hospitalisation for heart failure symptoms in last 3 months . This heart failure was because of stenosed Heart Valve. Only solution or treatment for this patient was to … Continue reading →

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Why I'm sure human stem cell trial will be safe – New …

Posted: Published on August 9th, 2015

(Image: Natasha Little) The new kind of stem cell announced yesterday may be the future of regenerative medicine, but Masayo Takahashis pilot safety study using a type of stem cell to treat age-related blindness is at the cutting edge Later this year, you will make history when you begin the first ever human trial of induced pluripotent stem cells. Why is this such a big deal? Stem cells have enormous medical potential because they can become any other type of cell. If we can use them to replace old or damaged cells, this could have huge implications for treating degenerative diseases. Stem cells can be harvested from embryos, but this is ethically controversial. Despite this, there are several trials of these embryonic stem cells under way. Their use often requires drugs to stop the immune system from rejecting them, which can cause complications for elderly patients. Induced pluripotent stem (iPS) cells offer an alternative. These are made from a patients own cells, removing the need for the immunosuppressant drugs. Plus there are no ethical issues. How would treatment with iPS cells work? iPS cells are made by injecting several reprogramming genes into adult cells that have been removed from the … Continue reading →

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DNA | chemical compound | Britannica.com

Posted: Published on August 9th, 2015

DNA,abbreviation of deoxyribonucleic acid, DNAEncyclopdia Britannica, Inc.organic chemical of complex molecular structure that is found in all prokaryotic and eukaryotic cells and in many viruses. DNA codes genetic information for the transmission of inherited traits. A brief treatment of DNA follows. For full treatment, see genetics: DNA and the genetic code. DNA: part of polynucleotide chainEncyclopdia Britannica, Inc.The chemical DNA was first discovered in 1869, but its role in genetic inheritance was not demonstrated until 1943. In 1953 James Watson and Francis Crick determined that the structure of DNA is a double-helix polymer, a spiral consisting of two DNA strands wound around each other. Each strand is composed of a long chain of monomer nucleotides. The nucleotide of DNA consists of a deoxyribose sugar molecule to which is attached a phosphate group and one of four nitrogenous bases: two purines (adenine and guanine) and two pyrimidines (cytosine and thymine). The nucleotides are joined together by covalent bonds between the phosphate of one nucleotide and the sugar of the next, forming a phosphate-sugar backbone from which the nitrogenous bases protrude. One strand is held to another by hydrogen bonds between the bases; the sequencing of this bonding is specifici.e., adenine bonds … Continue reading →

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Rash 101: The Most Common Types of Skin Rashes

Posted: Published on August 8th, 2015

Rash facts Rash is not a specific diagnosis. Instead it means skin inflammation and discoloration that changes the way the skin looks. Common rashes include eczema, poison ivy, hives, and heat rash. Infections that cause rashes may be fungal, bacterial, parasitic, or viral. Over-the-counter products may be helpful treatments for many skin rashes. Rashes lasting more than a few days that are unexplained should be evaluated by a doctor. What are the causes, symptoms, and signs of common noninfectious rashes? Some common, noninfectious rashes are listed below. If you have a new rash and you have a fever or some other generalized illness associated with it, it would be best to see your doctor. Seborrheic dermatitis: Seborrheic dermatitis is the single most common rash affecting adults. It produces a red scaling eruption that characteristically affects the scalp, forehead, brows, cheeks, and external ears. Atopic dermatitis: Atopic dermatitis, often called eczema, is a common disorder of childhood which produces red itchy, weeping rashes on the inner aspects of the elbows and in back of the knees as well as the cheeks, neck, wrists, and ankles. It is commonly found in patients who also have asthma and hay fever. Contact dermatitis: Contact … Continue reading →

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Learning About Duchenne Muscular Dystrophy

Posted: Published on August 8th, 2015

Learning About Duchenne Muscular Dystrophy What is Duchenne muscular dystrophy? Duchenne muscular dystrophy (DMD) is a rapidly progressive form of muscular dystrophy that occurs primarily in boys. It is caused by an alteration (mutation) in a gene, called the DMD gene that can be inherited in families in an X-linked recessive fashion, but it often occurs in people from families without a known family history of the condition. Individuals who have DMD have progressive loss of muscle function and weakness, which begins in the lower limbs. The DMD gene is the second largest gene to date, which encodes the muscle protein, dystrophin. Boys with Duchenne muscular dystrophy do not make the dystrophin protein in their muscles. Duchenne muscular dystrophy affects approximately 1 in 3500 male births worldwide. Because this is an inherited disorder, risks include a family history of Duchenne muscular dystrophy. Top of page The symptoms usually appear before age 6 and may appear as early as infancy. Typically, the first noticeable symptom is delay of motor milestones, including sitting and standing independently. The mean age for walking in boys with Duchenne muscular dystrophy is 18 months. There is progressive muscle weakness of the legs and pelvic muscles, which … Continue reading →

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Interview with Bioheart CSO, Kristin Comella: trial update …

Posted: Published on August 8th, 2015

I invited the Chief Scientific Officer (CSO) of Bioheart, Kristin Comella, to do an interview after hearing some buzzthat this couldbe a critical time for the company and that it might have been recently visited by the FDA. Note that Comella not just Bioheart CSO, but also the primary instructor for physician training in stem cell methods offered by the company US Stem Cell Training. Can you update us on how Bioheart is doing with its clinical trials/INDs? Comella: Our completed clinical trials of MyoCell to date have been primarily targeted to patients with severe, chronic damage to the heart who are in Class II or Class III heart failure according to the New York Heart Association, or NYHA, heart failure classification system. We have completed various clinical trials for MyoCell including the SEISMIC Trial, a 40patient, randomized, multicenter, controlled, Phase IIa study conducted in Europe and the MYOHEART Trial, a 20patient, multicenter, Phase I doseescalation trial conducted in the United States. We were approved by the FDA, to proceed with a 330patient, multicenter Phase II/III trial of MyoCell in North America and Europe, or the MARVEL Trial. Thus far, 20 patients, including 6 control patients, have been treated. Initial … Continue reading →

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Mesenchymal Stem Cell Therapy Trial for Multiple Sclerosis …

Posted: Published on August 7th, 2015

Mesenchymal stem cell therapy is one of two types of stem cell therapy that has been under investigation for treatment of multiple sclerosis. The other type is called hematopoietic stem cell therapy, and both have demonstrated varying degrees of benefit for MS patients. Although the two types of stem cell therapy have some significant differences, one of special importance is the fact that patients undergoing hematopoietic stem cell transplantation must first undergo extensive chemotherapy to eliminate an individuals defective immune system. This places patients at significant risk of infection. Mesenchymal stem cell therapy does not require this step. What is mesenchymal stem cell therapy? Mesenchymal stem cells are derived from adult bone marrow, skin and fat tissue, and umbilical cord blood. This therapy is still in the experimental stages and is being studied in multiple sclerosis for their ability to reduce inflammation, support the immune system, and help prevent and repair tissue damage. This therapeutic approach involves extracting mesenchymal stem cells from a patients own bone marrow and expanding them for several week in a specialized culture lab. The cells are frozen and then thawed before they are infused back into the same patient via an intravenous line. In hematopoietic … Continue reading →

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Spinal Cord Injury Treatment – Shriners Hospitals for Children

Posted: Published on August 5th, 2015

Each year 12,000 new cases of spinal cord injuries (SCI) are reported throughout the U.S. Approximately 10 percent of those affect children under age 16. In the mid-1980s, Shriners Hospitals for Children established the nations first SCI rehabilitation programs specifically designed for children and teenagers. At Shriners Hospitals for Children, an interdisciplinary team of surgeons and other physicians, therapists, therapeutic recreation specialists, psychologists, social workers and dieticians work together to provide individualized, comprehensive care plans for our patients with SCI. In addition to providing treatment, our staff works with the patients family members to help them understand the social, emotional and developmental implications of an SCI to help ensure the best possible outcome for the child, including the ability to have a full, productive life. Innovative therapies offered at Shriners Hospitals for Children include body-weight supported manual and automated treadmill training. Both of these methods provide weight-bearing opportunities and can help stimulate muscles and build strength and stamina. Our programs also offer functional electric stimulation (FES), which is a sophisticated, computerized system that sends small doses of electrical current to peripheral nerves, stimulating paralyzed muscles. FES can be used with specialized bikes to provide an opportunity for exercise. We also … Continue reading →

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