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Prothena Surges On Positive Phase I Results Of Parkinson''s Drug PRX002

Posted: Published on March 20th, 2015

By RTT News, March 19, 2015, 06:54:00 PM EDT (RTTNews.com) - Prothena Corp plc ( PRTA ), a late-stage clinical biotechnology company, on Thursday said a Phase I study of PRX002, its experimental Parkinson's disease drug, met its primary objective of safety and tolearability. Following the announcement, Prothena shares jumped more than 38% to $40.50 in after-hours trade on the Nasdaq. PRX002 is a monoclonal antibody for the potential treatment of Parkinson's disease and other related synucleinopathies. The drug is the focus of a worldwide collaboration between Prothena and Roche. In the Phase 1 single ascending dose study of PRX002, the drug was safe and well-tolerated. Further, results from the study showed that administration of PRX002 leads to mean reduction of free serum alpha-synuclein levels of up to 96%. These overall results were highly statistically significant. Reduction of free serum alpha-synuclein, a protein potentially involved in the onset and progression of Parkinson's disease and the target of PRX002, was shown to be robust, rapid and dose-dependent after just a single dose. The Phase 1 double-blind, placebo-controlled, single ascending dose study enrolled 40 healthy volunteers. No hypersensitivity reactions or drug-related serious adverse events were reported. PRX002 demonstrated favorable pharmacokinetic properties, supporting … Continue reading

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What is an Anoxic Brain Injury & what do I do if I have one? – Video

Posted: Published on March 20th, 2015

What is an Anoxic Brain Injury what do I do if I have one? Indianapolis injury attorney Tom Doehrman of Doehrman Buba explains how medical negligence during childbirth can cause baby brain injuries and cerebral palsy. TRANSCRIPT: When a person's... By: Doehrman Buba … Continue reading

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America's Aging Population Will Require More Neurosurgeons to Handle Increased Brain Bleeds

Posted: Published on March 20th, 2015

Contact Information Available for logged-in reporters only Newswise (New York, NY) -- By 2030, chronic subdural hemorrhage (SDH) will be the most common adult brain condition requiring neurosurgical intervention in the U.S., according to a new study conducted by researchers at NYU Langone Medical Center. And hospitals and neurosurgeons may be under-manned to handle the projected onslaught of patients. The researchers are publishing their findings March 20 online in the Journal of Neurosurgery. Subdural hemorrhage also known as subdural hematoma is bleeding on the surface of the brain, usually caused by trauma to the head. It is more common in the elderly because of increased brain atrophy, greater use of anti-coagulant medications and thinning of the delicate vessels stretching between the surface of the brain and its coverings. As a consequence, even minor head injuries can result in bleeding on the surface of the brain that can accumulate over time and lead to serious complications. The causative trauma can be so minor that, in fact, many people with SDHs have no history or recollection of a head or brain trauma incident. SDHs are also more common in military veterans and in people with a history of alcohol abuse. While clinicians … Continue reading

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MS Dhoni's Childhood Coach Granted One Lakh Rupees for Treatment by Jharkhand Government

Posted: Published on March 20th, 2015

MS Dhoni's coach was helped out by the Jharkhand Government Ranchi: Jharkhand Chief Minister Raghubar Das today announced Rupees one lakh for the treatment of ailing Chanchal Bhattacharya, who is a former coach of India cricket captain MS Dhoni. Calling on Bhattacharya, Das said the veteran coach would get the monetary assistance from the Chief Minister's Relief Fund, stated an official release. (Dhoni Joins Aussie Greats With a Century of ODI Victories) Wishing him speedy recovery, Das said if required he would also provide aid in his personal capacity. "Bhattacharya is ailing for over one year. He is known as the 'guru' of Mahendra Singh Dhoni, whom he coached during his formative years of cricket," the release said. (India Score 11th Straight Win in World Cups) Bhattacharya, who claims to have persuaded Dhoni to take up cricket over his first love football during a district level cricket tournament, is keenly following India's campaign in the ongoing World Cup. "India are two matches away from the coveted cup. I am praying to the Almighty that India repeats history," Bhattacharya said as he congratulated Team India entering the semi-final after beating Bangladesh earlier in the day. See original here: MS Dhoni's Childhood … Continue reading

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Recursion Pharmaceuticals Announces Funding Support for Ataxia-Telangiectasia

Posted: Published on March 20th, 2015

Recursion today announced a grant from the AT-Children's Project to advance it's innovative drug discovery work towards identifying novel treatments for ataxia-telangiectasia, a brutal childhood genetic disease. Ataxia-telangiectasia (A-T) is a rare genetic disease that attacks children, causing progressive loss of muscle control, immune system problems, and a high rate of cancer. The award will be used to support Recursions efforts to build a many-dimensional cellular model of the disease to be used in future drug screening efforts. Chris Gibson, Ph.D., CEO of Recursion Pharmaceuticals remarked: We are grateful to the A-T Childrens Project for this award which will enable us to rapidly deploy our innovative drug discovery technology towards Ataxia-telangiectasia. As a young company, the support and trust of foundations like the A-T-Childrens Project is critical to our ability to apply our technology across as many diseases as possible. Recursions technology, which combines experimental biology and bioinformatics, is especially useful for drug discovery in rare genetic diseases where our understanding of the complete molecular picture of the diseases is lacking. A-T, which is due to mutations in the gene ATM, is just such a disease. Loss of function of ATM results in myriad complex and interconnected molecular changes in … Continue reading

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Baby Joy IVF Centre India | Baby Joy IVF Corporate Video Delhi | IVF Treatment Centre India – Video

Posted: Published on March 20th, 2015

Baby Joy IVF Centre India | Baby Joy IVF Corporate Video Delhi | IVF Treatment Centre India Bay Joy IVF Hospitals in a Specialist Doctors, IVF Clinics Delhi, IVF Centres, IVF clinic Delhi india, Test tube baby Clinic in Delhi, Baby Joy Surrogacy in Delhi For more info - http://www.babyj... By: Baby Joy … Continue reading

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Celebrities Slam Dolce & Gabbana & Join Boycott After IVF Diss

Posted: Published on March 20th, 2015

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Spring Fling Genetics Seminar AI Panel – Video

Posted: Published on March 20th, 2015

Spring Fling Genetics Seminar AI Panel The second session of the morning was the AI-Panel. It was made up of 6 past and present AI Sire Analysis's. Roger Turned asked The group questions about how each of them work with breeders.... By: HolsteinWorld MOOTUBE … Continue reading

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The Genetics Of Spirit (Clip) – Sunday Conversations With Roy Masters – Video

Posted: Published on March 20th, 2015

The Genetics Of Spirit (Clip) - Sunday Conversations With Roy Masters The Genetics Of Spirit (Clip) - From Sunday Conversation # 8608 - "Life and the Sin Factor" Recorded March 8th 2015 Watch On This Channel Or At https://www.fhu.com/sunday-conversations/#watch... By: FHUDOTCOM … Continue reading

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PLoS Genetics : Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation… – Video

Posted: Published on March 20th, 2015

PLoS Genetics : Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation... Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation of Silencer Elements in a Large Gene Desert of Chromosome 10. Karl-F. Bergeron et al (2015), PLoS Genetics ... By: KeSimpulan … Continue reading

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