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Farmington startup treats MS in mice with stem cells

Posted: Published on June 6th, 2014

A pre-clinical biotech startup that was awarded more than $1 million in state money last year said it has demonstrated that a certain type of abundant stem cells significantly reduce the severity of multiple sclerosis in mice. Farmington's ImStem Biotechnology Inc., which is a member of UConn's technology incubator, said it worked with UConn Health Center scientists and Massachusetts company Advanced Cell Technology Inc. to determine that mesenchymal stem cells (MSCs) derived from human embryonic stem cells are more effective at treating MS in mice than MSCs from the bone marrow of adult donors. In fact, the researchers said they found unexpectedly that the use of adult bone marrow stem cells to treat MS is highly variable and may carry a previously unrecognized risk of poor outcome. The work is published in the June 5 online edition of Stem Cell Reports. ImStem is seeking approvals and investment for Phase 1 clinical trials. See the original post here: Farmington startup treats MS in mice with stem cells … Continue reading

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Bioinformatics | Johns Hopkins University Engineering for …

Posted: Published on June 6th, 2014

Program Overview Discovery of new drug therapies increasingly stems from our growing knowledge of genomics, our ability to manage huge amounts of sequence data, and our ability to uncover secrets hidden within the genetic code. As a result, professionals operating at the intersection of biological systems, genetics, and information technology have become key to medical advances and are in high demand. The Bioinformatics program at Johns Hopkins Engineering for Professionals combines the strengths of the Zanvyl Krieger School of Arts and Sciences' Advanced Academic Programs and Johns Hopkins Engineering for Professionals to produce graduates who can excel in the field. One of the most comprehensive bioinformatics master's programs available anywhere, the program gives students the educational foundation needed to interpret complex biological information, perform analysis of sequence data using sophisticated bioinformatics software, and develop program software when needed. Highlights include: All applications for this program must be submitted directly to Advanced Academic Programs. An asterisk (*) denotes a course offered only through Advanced Academic Programs. Link: Bioinformatics | Johns Hopkins University Engineering for ... … Continue reading

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2014 Epilepsy Pipeline Conference Day 2 – Video

Posted: Published on June 6th, 2014

2014 Epilepsy Pipeline Conference Day 2 On June 5-7, 2014 in San Francisco, CA, the Epilepsy Therapy Project, an initiative of the Epilepsy Foundation will present the 4th Biennial Pipeline Conference 2014, to be held at the Hyatt... By: EpilepsyFoundation … Continue reading

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Dr. Steven N. Rice Continues to Honor Stroke Awareness Month by Increasing the Awareness of the Connection Between …

Posted: Published on June 6th, 2014

Gaithersburg, MD (PRWEB) June 04, 2014 Gaithersburg patients can honor Stroke Awareness Month with Dr. Steven N. Rice, a leading periodontist with the Advanced Laser Gum Surgery- Institute of Washington. Dr. Rice aims to bring awareness to the connection between periodontal disease and incidences of stroke, and hopes that offering his Gaithersburg patients gum disease treatment options as a preventative measure will reduce the numbers of individuals suffering from this devastating and deadly illness in the future. Stoke occurs when the brains oxygen supplying blood vessels become damaged or compromised, leading to decreased amounts of oxygen in affected parts of the brain. Entire sections of the organ can be severely impaired, often resulting in complete functional loss in the area. It is a debilitating occurrence that often results in the loss of various motor and neurological functions, including a persons ability to use their limbs, speak, and hear. Stroke is a very serious problem for Americans, with 1 person suffering from an episode every 45 seconds. It is a leading cause of death across the nation, and can seem to strike without warning. Scientists have discovered a connection between periodontal disease and stroke. Recent studies show that individuals who suffer … Continue reading

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New Resource Center for Parents of Children with Cerebral Palsy

Posted: Published on June 6th, 2014

New York, NY (PRWEB) June 05, 2014 The birth injury patient advocates at CerebralPalsyHelp.org are announcing the launch of a new national resource site for parents of children affected by the neurological disorder. The CP Help Center will provide the latest on cerebral palsy research, treatment, causes and litigation news. Parents can learn more about their childs condition and how it may have been caused, get information on charities and other assistance, and decide if they should seek legal advice. Cerebral palsy is a classification of neurological disorders affecting muscle movement, coordination and posture. It is the leading cause of functional and developmental disability in children in the United States*, occurring in approximately 3.3 out of every 1,000 births, or around 10,000 infants per year*. While cerebral palsy affects muscle function, it is not a disorder of the muscles or nerves; rather, it is caused by brain damage to parts that control muscle function**. This usually occurs before, during or after birth**. Cerebral palsy may be caused by a number of factors affecting the fetus during pregnancy, or by trauma or asphyxiation during labor**. Unfortunately, there is no cure for cerebral palsy at this time. However, several treatment options are … Continue reading

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Rebecca Powell – Roger C. Peace Rehabilitation Hospital – Video

Posted: Published on June 6th, 2014

Rebecca Powell - Roger C. Peace Rehabilitation Hospital Rebecca Powell's life changed in just seconds on July 8, 2011. Hear her story about going through Traumatic Brain Injury treatment and rehabilitation, and wh... By: GHSGiving … Continue reading

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Traumatic brain injury Treatments and drugs – Diseases and …

Posted: Published on June 6th, 2014

Mild injury Mild traumatic brain injuries usually require no treatment other than rest and over-the-counter pain relievers to treat a headache. However, a person with a mild traumatic brain injury usually needs to be monitored closely at home for any persistent, worsening or new symptoms. He or she also may have follow-up doctor appointments. The doctor will indicate when a return to work, school or recreational activities is appropriate. It's best to avoid physical or thinking (cognitive) activities that make things worse until symptoms have resolved. Most people return to normal routines gradually. Emergency care for moderate to severe traumatic brain injuries focuses on making sure the person has an adequate oxygen and blood supply, maintaining blood pressure, and preventing any further injury to the head or neck. People with severe injuries may also have other injuries that need to be addressed. Additional treatments in the emergency room or intensive care unit of a hospital will focus on minimizing secondary damage due to inflammation, bleeding or reduced oxygen supply to the brain. Medications to limit secondary damage to the brain immediately after an injury may include: Anti-seizure drugs. People who've had a moderate to severe traumatic brain injury are at … Continue reading

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Leon O'Neill left brain damaged after reaction to glandular fever drugs

Posted: Published on June 6th, 2014

Leon O'Neill developed leukaemia when he was just four years old He had years of treatment but the cancer returned in February 2013 After a bone marrow transplant he spent weeks in isolation in hospital Just after returning home, he picked up the glandular fever virus Leon was given urgent treatment but suffered a devastating reaction His brain was starved of oxygen and he is now in a vegetative state His parents Caroline and Shaun have been warned that he will not recover By Emma Innes Published: 06:52 EST, 5 June 2014 | Updated: 07:07 EST, 5 June 2014 232 shares 16 View comments A 10-year-old boy who twice fought cancer suffered irreparable brain damage when he reacted to drugs prescribed for glandular fever. Leon ONeill is now in a vegetative state, with doctors warning his devastated parents he will not recover. Caroline Bottrell and Shaun O'Neill are today desperately trying to raise enough money to modify their house, so they can bring their son home from hospital. Leon was diagnosed with leukaemia when he was just four and had three years of chemotherapy before going into remission. See more here: Leon O'Neill left brain damaged after reaction to glandular … Continue reading

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Future heat stroke treatment found in dental pulp stem cells

Posted: Published on June 6th, 2014

PUBLIC RELEASE DATE: 5-Jun-2014 Contact: Robert Miranda cogcomm@aol.com Cell Transplantation Center of Excellence for Aging and Brain Repair Putnam Valley, NY. (June 5, 2014) Scientists in Taiwan have found that intravenous injections of stem cells derived from human exfoliated deciduous tooth pulp (SHED) have a protective effect against brain damage from heat stroke in mice. Their finding was safe and effective and so may be a candidate for successfully treating human patients by preventing the neurological damage caused by heat stroke. The study is published in a future issue of Cell Transplantation and is currently freely available on-line as an unedited early e-pub at: http://www.ingentaconnect.com/content/cog/ct/pre-prints/content-CT1100Tseng. "Heat stroke deaths are increasing worldwide and heat stroke-induced brain injury is the third largest cause of mortality after cardiovascular disease and traumatic brain injury," said study lead author Dr. Ying-Chu Lin of the Kaohsiung Medical University School of Dentistry, Kaohsiung City, Taiwan. "Heat stroke is characterized by hyperthermia, systemic inflammatory response, multiple organ failure and brain dysfunction." To investigate the beneficial and potentially therapeutic effects afforded by the protective activities of self-renewing stem cells derived from human exfoliated deciduous teeth, the scientists transplanted SHED into mice that had suffered experimental heat stroke. According to … Continue reading

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New treatment for MS is approved for use on NHS

Posted: Published on June 6th, 2014

New treatment for MS is approved for use on NHS 10:00pm Thursday 5th June 2014 in News MULTIPLE sclerosis sufferers have been given a boost after a new treatment developed by an Oxford firm was approved to be available on the NHS. The National Institute for Health and Care Excellence (Nice) has sanctioned the use of Genzymes Lemtrada therapy to treat active relapsing remitting multiple sclerosis (RRMS), which accounts for 85 per cent of initial diagnoses of the disease. Brendan Martin, general manager for Genzyme UK and Ireland based at the Oxford Business Park, said: This final milestone brings a treatment option to people with MS that could really reshape the management of their condition. We are also immensely proud of our association with Lemtrada as a home-grown product, developed by a team of UK scientists. About 100,000 people in the UK have MS and about 2,500 people are diagnosed with it each year. Lemtrada is an antibody therapy which targets CD52, a protein thought to be responsible for the inflammatory process in MS. The treatment is the second of Genzymes treatments for MS to receive approval for NHS use. Our top stories: See the rest here: New treatment for … Continue reading

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