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Neurologists report on promise of statins, estrogen, telemedicine in Parkinson's

Posted: Published on April 29th, 2014

A trio of studies from the Perelman School of Medicine at the University of Pennsylvania demonstrate new approaches to understanding, treating and potentially staving off Parkinson's disease (PD). Studies show that factors such as estrogen exposure and statin use have an impact on the onset of Parkinson's disease. And a new look at telemedicine demonstrates feasibility in providing care for Parkinson's patients using remote video visits to expand access and center care around the needs of Parkinson's patients. These studies and more will be presented at the American Academy of Neurology's 66th Annual Meeting at Philadelphia's Pennsylvania Convention Center from April 26 to May 3, 2014. "Researchers at Penn Medicine are looking at Parkinson's disease from all angles -- ways to improve treatment methods for those currently battling the disease, understanding the root causes of disease, and identifying potential interventions to delay the onset of disease," said Matthew Stern, MD, professor of Neurology in the Perelman School of Medicine at the University of Pennsylvania and director of Penn's Parkinson's Disease and Movement Disorders Center. "We are persistent and eager to find better targets and treatments to help patients with Parkinson's disease, which affects up to 1 million Americans and 10 … Continue reading

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Multiple Sclerosis Treatment & Management

Posted: Published on April 29th, 2014

Services and Web Sites Covered This policy describes what information may be collected about you when you use the services made available through the WebMD Health Professional Network (as defined below), how this information may be used, how you can control how your information is used and what precautions are taken against unauthorized access or use of your information. The services made available through the WebMD Health Professional Network may be provided in a variety of mediums and devices now known or hereinafter developed including mobile applications, and include without limitation news, reference tools and applications, sponsored programming, personalized content, continuing medical education, communication tools and discussion boards (collectively, the "Services"). You should read the privacy policy of each website that you visit after you leave any of the WebMD Health Professional Network websites. We are not responsible for how other websites treat your privacy once you leave one of our websites. The WebMD Health Professional Network is comprised of several websites including medscape.com, medscape.org, medscape.fr and medscapedeutschland.de (referred to collectively as the "Professional Sites"), including any mobile optimized versions of the Professional Sites and the Medscape Mobile Device Application ("Medscape Mobile"). These properties are owned and operated by our … Continue reading

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Just to be able to use my hands again would be great, says Lowestoft woman in fight for multiple sclerosis drug

Posted: Published on April 29th, 2014

Shona Garrett suffers from MS but is unable to access a drug that may be able to ease her symptoms. Picture: James Bass Kathryn Bradley Tuesday, April 29, 2014 9:29 AM People living with multiple sclerosis (MS) in Norfolk and Suffolk could be left behind if life-changing medicines continue to be out of reach for many sufferers, a leading charity has warned. To send a link to this page to a friend, you must be logged in. Sativex is a peppermint-flavoured mouth spray that comes in a small pump that people can carry with them. The medicine in Sativex is extracted from cannabis plants that have been selected and grown to produce a constant amount of active ingredients that have been shown to help improve the symptoms of MS spasticity. The NHS has a legal obligation to fund all treatments that NICE recommends but currently this does not include Sativex. A spokesman for Bayer Healthcare, which produces Sativex, said the NICE guidelines for the management of MS were due to be revised and the company was anticipating that Sativex would be included within these. The MS Society is calling for all drugs licensed for the treatment of MS to be … Continue reading

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Medical marijuana may treat MS symptoms, ineffective for other brain disorders

Posted: Published on April 29th, 2014

As medical marijuana makes its way into mainstream clinical use, there is still much mystery surrounding the drug, as not much is known about the its effects on the brain or nervous system disorders. To gain a better understanding of the benefits or downsides of medical cannabis, researchers from the American Academy of Neurology conducted a systematic review of available research analyzing the use of marijuana for the treatment of brain diseases. Through their analysis, they found that medical marijuana can help alleviate some symptoms of multiple sclerosis (MS), but the drug was not very successful at treating drug-induced movements from Parkinsons disease. Additionally, there was insufficient evidence to support whether or not marijuana can treat motor problems in Huntingtons disease, tics in Tourette syndrome, or seizures in epilepsy. According to the researchers, they were interested in reviewing medical marijuanas effects on brain disorders, as so many patients have started using it as a form of treatment without a prescription. Ive known my patients for a long time; they use it, and some will tell me which symptoms they thought it was helpful for, review author Dr. Barbara Koppel, of New York Medical College and fellow of the American Academy … Continue reading

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AAN Issues Findings on Use of Medical Marijuana in Treatment of Certain Brain Diseases

Posted: Published on April 29th, 2014

Contact Information Available for logged-in reporters only Newswise MINNEAPOLIS A review by the American Academy of Neurology of available scientific research on the use of medical marijuana in brain diseases finds certain forms of medical marijuana can help treat some symptoms of multiple sclerosis (MS), but do not appear to be helpful in treating drug-induced (levodopa) movements in Parkinsons disease. Not enough evidence was found to show if medical marijuana is helpful in treating motor problems in Huntingtons disease, tics in Tourette syndrome, cervical dystonia and seizures in epilepsy. The review is published in the April 29, 2014, print issue of Neurology, the medical journal of the American Academy of Neurology (AAN), and will be presented at the AAN Annual Meeting in Philadelphia, April 26-May 3, 2014, which is the worlds largest gathering of neurologists. This review by the worlds largest association for neurologists is intended to help neurologists and their patients understand the current research on medical marijuana for the treatment of certain brain diseases, said review author Barbara S. Koppel, MD, of New York Medical College in New York and Fellow of the American Academy of Neurology. The AAN review also highlights the need for more high-quality studies … Continue reading

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Stem cell cloning may be aid treatment for diabetes

Posted: Published on April 29th, 2014

Scientists have moved one step closer to creating and effective diabetes treatment by creating insulin-producing cells with the DNA of a diabetic woman. The approach could someday aid treatment of the Type 1 form of the illness, which is usually diagnosed in childhood and accounts for about 5 percent of diabetes cases in the U.S. The disease kills insulin-making cells in the pancreas. People with Type 1 diabetes use shots or a small pump to supply the hormone, which is needed to control blood sugar. The new work is a step toward providing genetically matched replacement cells for transplant, said Dieter Egli of the New York Stem Cell Foundation Research Institute in New York. He led the research, which was reported online Monday in the journal Nature. Doug Melton of the Harvard Stem Cell Institute, who was not involved with the work, called the paper an impressive technical achievement. But he said he believed the cells would be useful as a research tool rather than a source of transplants. They could help scientists uncover what triggers Type 1 diabetes, he said, which could in turn lead to better therapies. Scientists had previously made insulin cells that match diabetic patients by … Continue reading

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Genetic mutations involved in human blood diseases identified

Posted: Published on April 29th, 2014

A study published today in Nature Genetics has revealed mutations that could have a major impact on the future diagnosis and treatment of many human diseases. Through an international collaboration, researchers at the Montreal Heart Institute (MHI) were able to identify a dozen mutations in the human genome that are involved in significant changes in complete blood counts and that explain the onset of sometimes severe biological disorders. The number of red and white blood cells and platelets in the blood is an important clinical marker, as it helps doctors detect many hematological diseases and other diseases. Doctors can also monitor this marker to determine the effectiveness of therapy for certain pathologies. "Complete blood counts are a complex human trait, as the number of cells in the blood is controlled by our environment and the combined expression of many genes in our DNA," explained Dr. Guillaume Lettre, a study co-author, an MHI researcher, and an Associate Professor at the Faculty of Medicine at Universit de Montral. In collaboration with their colleagues at the University of Washington in Seattle and the University of Greifswald in Germany, these MHI researchers analyzed the DNA of 6,796 people who donated specimens to the MHI … Continue reading

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Study of stem cell trials links discrepancies in data with reported success of treatment

Posted: Published on April 29th, 2014

PUBLIC RELEASE DATE: 28-Apr-2014 Contact: Franca Davenport f.davenport@imperial.ac.uk 020-759-42198 Imperial College London New research looking at the success of clinical trials of stem cell therapy shows that trials appear to be more successful in studies where there are more discrepancies in the trial data. Researchers from Imperial College London conducted a meta-analysis of 49 randomised controlled trials of bone marrow stem cell therapy for heart disease. The study, published today in the British Medical Journal, identified and listed over 600 discrepancies within the trial reports. Discrepancies were defined as two (or more) reported facts that could not both be accurate because they were logically or mathematically incompatible. For example, one trial reported that it involved 70 patients, who were divided into two groups of 35 and 80. The researchers found eight trials that each contained over 20 discrepancies. The researchers found that the discrepancy count in a trial was the most important determinant of the improvement in cardiac function reported by that trial. Trials with fewer and fewer discrepancies showed progressively smaller improvements in cardiac function. The five trials with no discrepancies at all showed an effect size of zero (see bar chart in Notes to Editors). Previous meta-analyses looking … Continue reading

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Stem Cell Institute Welcomes Special Guest Speaker Roberta F. Shapiro DO, FAAPM&R to Stem Cell Therapy Public Seminar …

Posted: Published on April 29th, 2014

New York, NY (PRWEB) April 29, 2014 The Stem Cell Institute located in Panama City, Panama, welcomes special guest speaker Roberta F. Shapiro, DO, FAAPM&R to its public seminar on umbilical cord stem cell therapy on Saturday, May 17, 2014 in New York City at the New York Hilton Midtown from 1:00 pm to 4:00 pm. Dr. Shapiro will discuss A New York Doctors Path to Panama. Dr. Shapiro operates a private practice for physical medicine and rehabilitation in New York City. Her primary professional activities include outpatient practice focused on comprehensive treatment of acute and chronic musculoskeletal and myofascial pain syndromes using manipulation techniques, trigger point injections, tendon injections, bursae injections, nerve and motor point blocks. Secondary work at her practice focuses on the management of pediatric onset disability. She is the founder and president of the Dayniah Fund, a non-profit charitable foundation formed to support persons with progressive debilitating diseases who are faced with catastrophic events such as surgery or illness. The Dayniah Fund educates the public about the challenges of people with disabilities and supports research on reducing the pain and suffering caused by disabling diseases and conditions. Dr. Shapiro serves as assistant clinical professor in the … Continue reading

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Cloning: Scientists make insulin-producing cells

Posted: Published on April 29th, 2014

It was not the first study to create stem cells in this way, but it was the first to use cells sourced from a diseased adult person with the aim of producing therapy-specific cells. FEATURE Scientists said yesterday they had used cloning technology to make embryonic stem cells that carry a diabetic womans genes, and turned them into insulin-producing beta cells that may one day cure her disease. The team reported clearing an important hurdle in the quest to make personalised stem cells for use in disease therapy, but a bioethicist said the breakthrough also highlighted the need for better regulation of lab-grown embryos. We are now one step closer to being able to treat diabetic patients with their own insulin-producing cells, said Dieter Egli of the New York Stem Cell Foundation (NYSCF), who led the study published in the journal Nature. Egli and a team had transplanted the nuclei of cells taken from the womans skin into human eggs to create stem cells, which they could then coax into becoming beta cells a shortage of which causes insulin deficiency and high blood-sugar in diabetics. In doing so, the team confirmed a potentially important source for future cell-replacement therapy. It … Continue reading

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