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MS Walk set for Sunday in Boca

Posted: Published on March 19th, 2014

Jodi Rothman has been raising money to help treat and cure multiple sclerosis since her daughter Alie was diagnosed at 14. Now Alie's 22 and in law school at the University of Miami. She's about to launch her nonprofit for children with MS who can't afford treatment, on a national level. And this year, the family team in her name hopes to raise $90,000 to $100,000 in Walk MS in Boca on Sunday, and another $50,000 or so at two other walks in the state, said Jodi Rothman, of western Delray Beach, who has been the walk's chairwoman for three years. Check-in opens at 7:30 a.m. and the UAIC Boca Raton Walk MS presented by Genzyme starts at 9 a.m. at the Boca Corporate Center & Campus, 500 T-Rex Ave. The chapter expects a turnout of at least 600 people and raised nearly $300,000 last year. Supporters can register or volunteer at mswalksouthflorida.org or call 800-344-4867. A $50 fundraising goal for adults and $25 for students 13 to 17 is required; walk participants who raise at least $100 will receive a T-shirt and additional prize levels. "South Florida residents demonstrate support for those living with multiple sclerosis by raising more … Continue reading →

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Statins May Be Effective In Treating Secondary Progressive Multiple Sclerosis

Posted: Published on March 19th, 2014

March 19, 2014 Brett Smith for redOrbit.com Your Universe Online At first, multiple sclerosis is recognized by sporadic neurological symptoms a condition called relapsing-remitting MS. Within a decade or so, greater than 50 percent of patients acquire secondary progressive MS, a continuous deterioration of symptoms and boost in disability. Currently, there are no approved drugs for treating this later stage of the disease. However, a newly published study in the UK medical journal The Lancet has shown surprising evidence of a promising treatment for this second phase of MS cholesterol-lowering statins. At the moment, we dont have anything that can stop patients from becoming more disabled once MS reaches the progressive phase, said study author Dr. Richard Nicholas, from the Department of Medicine at Imperial College London. Discovering that statins can help slow that deterioration is quite a surprise. This is a promising finding, particularly as statins are already cheap and widely used. Previous studies have shown statins to have an anti-inflammatory and protective effect on the nervous system. A preliminary clinical study of simvastatin in individuals with early-stage MS revealed fewer brain lesions, indicating an impact on the underlying disease process. However, following trials have had inconsistent results. In … Continue reading →

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FDA Grants Fast Track Designation To Edison Pharma's EPI-743

Posted: Published on March 19th, 2014

By Estel Grace Masangkay The U.S. Food and Drug Administration (FDA) has granted Fast Tack designation to Edison Pharmaceuticals lead drug EPI-743 for the treatment of Friedreichs ataxia. Guy Miller, Chairman and CEO of Edison Pharmaceuticals, said Fast Track designation will facilitate Edison's clinical development of EPI-743 for patients with Friedreich's ataxia. We are fully committed to delivering the first approved drug for this highly debilitating and lethal disease for which there are no FDA-approved therapies. EPI-743 is an orally bioavailable small molecule that belongs to the para-benzoquinone class of drugs. The companys lead drug is currently being developed for pediatric and adult mitochondrial disease including Friedreichs ataxia. EPI-743 has completed Phase I and Phase II studies, where it demonstrated safety and tolerability. A randomized, double blind, placebo controlled Phase II B trial in adults with Friedreichs ataxia is fully enrolled and expected to be completed in the third quarter of this year. Friedreichs ataxia is a rare autosomal recessive nuclear DNA inherited mitochondrial disease. It affects approximately 1 in 50,000 individuals. The disease is caused by a defect in the gene frataxin and manifests itself in energy failure symptoms, leaving patients with ataxia, muscle weakness, heart failure, and diabetes. … Continue reading →

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FDA Grants Fast Track Status to Edison Pharmaceuticals' EPI-743 for Friedreich's Ataxia

Posted: Published on March 19th, 2014

Downingtown, PA, (PRWEB) March 19, 2014 Edison Pharmaceuticals announced today that the U.S. Food and Drug Administration (FDA) has granted Fast Track Status to EPI-743 for the treatment of Friedreichs ataxia (http://www.prnewswire.com/news-releases/fda-awards-fast-track-status-to-edison-pharmaceuticals-epi-743-for-friedreichs-ataxia-250558901.html). This status will further accelerate the clinical development of EPI-743 now under way in two phase 2b clinical trials at three sites in the Friedreich's Ataxia Research Alliance (FARA) Collaborative Clinical Research Network. When the FDA grants the Fast Track designation, the Agency encourages early and more frequent meetings and communications with the drug company throughout the drug development and review process to ensure that any questions and issues are resolved quickly. With this status, the drug may also benefit from "rolling review," which permits the drug company to submit completed portions of its application for approval (New Drug Application) for immediate review by the FDA, instead of waiting for the entire application to be completed. These multiple benefits are intended to result in substantially faster drug approval and earlier treatment access by patients. The phase 2b clinical trial of EPI-743 in Friedreich's ataxia adults has been under way since early 2013 at the University of South Florida, the Children's Hospital of Philadelphia and the University of California … Continue reading →

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New Video Reveals HRC Medical Sales Tactics

Posted: Published on March 19th, 2014

by Jennifer Kraus Consumer Investigator NASHVILLE, Tenn.-- Hormone replacement therapy was a multimillion-dollar business for one Nashville company, but did high pressure sales tactics put patients at risk? We now have an inside look at the way HRC Medical tried to entice people to sign up for its lucrative and controversial program. The state shut down HRC for deceptive business practices after NewsChannel 5 Investigates raised questions about patients being overdosed on hormones at its Nashville clinic. Now, a training video produced by HRC Medical for its clinics around the country has surfaced. It was supposed to teach the company's salespeople how to get patients to commit to a year's worth of hormone therapy -- without undergoing a single medical test. Don Hale, one of the two founders of HRC Medical, appears in the nearly 12-minute video, explaining how HRC wants its salespeople to "close the deal." "What I'm going to try to do today is give you an outline of what to do in a consult and how we want it handled," Hale said in the video. The video was shown in court as part of the state's long running lawsuit against Don Hale and his brother Dan, who … Continue reading →

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Hormone replacement therapys effects free seminar at UT Health Northeast

Posted: Published on March 19th, 2014

(KYTX) - For many women, menopause and its symptoms have a profound impact on the quality of their lives. Menopause can also increase a woman's risk for developing conditions such as diabetes, heart disease, and osteoporosis. At "Hormone Replacement Therapy (HRT): What Does It Mean for Conditions Like Dementia, Heart Disease, and Osteoporosis?" to be held from 10 a.m. to 11:30 a.m. Tuesday, March 25, at UT Health Northeast, gynecologist Dr. Ralph Turner will talk about HRT's benefits, as well as its risks. Dr. Turner is nationally certified to treat health problems associated with menopause. He has successfully treated women with menopause for over 30 years. The free health education seminar will take place in the Academic Center Amphitheater on the UT Health campus, located at the intersection of U.S. 271 and State Highway 155. The seminar is part of "HealthConnection.tv: The Lecture Series. At http://www.HealthConnection.tv , UT Health physicians and medical professionals answer questions on topics like acid reflux, arthritis, pulmonary disease, and other conditions. Originally posted here: Hormone replacement therapys effects free seminar at UT Health Northeast … Continue reading →

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Stem Cell Research Vs. Fundamentalism – Video

Posted: Published on March 19th, 2014

Stem Cell Research Vs. Fundamentalism By: carpo719 … Continue reading →

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Stem cell research gets $500,000 boost

Posted: Published on March 19th, 2014

UC Merced professor Kara McCloskey was recently awarded a highly competitive $500,000 grant to continue research in human stem cell biology, as part of an effort to enhance stem cell research in California. In February, the California Institute for Regenerative Medicine approved more than $27million for Basic Biology V Awards, and McCloskeys grant is included. The leads for this effort include Stanford University and the Salk Institute for Biological Studies. In her laboratory, McCloskey and her students are using stem cells to engineer cardiovascular tissues that could someday be used to repair damaged blood vessels or heart tissue. Specifically, they are producing highly specialized cells that have not been the focus of much research to date the endothelial cells found at the tips and in the stalks, including phalanx endothelial cells, of blood vessels and cells that could help repair a damaged heart. The phalanx cells exhibit anti-inflammatory properties, and the ones in the tips and stalks contribute to angiogenesis, the new growth of blood vessels, said McCloskey, who teachers in the School of Engineering. The two-year grant will help support her laboratory, including five undergrads, five graduate students and one post-doctoral scholar as they gather the data that takes … Continue reading →

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Billionaire philanthropist Jim Stowers dies at 90

Posted: Published on March 19th, 2014

Jim Stowers, who died this week at age 90, became a billionaire by shrewdly investing other peoples money. After both he and his wife, Virginia, were diagnosed with cancer, they gave away most of their fortune to find cures for cancer and other deadly diseases. They established a world-class institute in their hometown of Kansas City. In 2006, the institutes medical research was threatened when Missouri legislators tried to criminalize some forms of embryonic stem cell research. The couple almost single-handedly bankrolled the fight to pass a constitutional amendment to protect a form of embryonic research. Voters narrowly approved the amendment in a bitter statewide battle. He provided most of the funds for the campaign, Dr. William Danforth, chancellor emeritus at Washington University, recalled Tuesday. The two wealthy men, from opposite ends of the state, joined forces in 2006 to create Missouri Cures. The organization won passage of the amendment with a sea of TV ads. Opponents called the funding clone-to-kill money. Danforth said Mr. Stowers was committed to making the world a better place. He recruited some of the best scientists and physicians to the Stowers Institute for Medical Research, putting Kansas City on the map for disease and … Continue reading →

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Jim Stowers Jr., 90, gave fortune to fight disease

Posted: Published on March 19th, 2014

1:00 AM The Kansas City man funded stem cell research. The Associated Press KANSAS CITY, Mo. Jim Stowers Jr., the billionaire founder of one of the nations leading investment management firms who gave away most of his fortune to fight disease, has died. He was 90. The Kansas City, Mo., philanthropist, whose tenacity in business was just as fierce as in his fight for stem-cell research, died Monday after a period of declining health, according to a news release issued by his namesake research firm and the investment firm he founded, American Century Investments. Stowers was a struggling mutual fund salesman in 1958 when he founded Twentieth Century Investors Inc. with only two mutual funds and $107,000 in assets. That company grew into American Century Investments, one of the nations leading investment management firms that, as of 2013, was managing about $141 billion. In 2000, Stowers and his wife, Virginia, who both successfully fought cancer, promised more than $1 billion of their fortune to create the Stowers Institute for Medical Research in Kansas City. Stowers and his wife said they wanted the institute to focus on basic research into how genes work, to determine ways to alter genes to fight … Continue reading →

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