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Researchers hope to grow human ears from fat tissue

Posted: Published on March 4th, 2014

Researchers at London's Great Ormond Street Hospital aim to grow a human ear via stem cells taken from a patient's fat tissue. Relatively little attention has been given to the reconstruction of damaged cartilage around the cranial area, however the new method is hoped to modernize this area of reconstructive surgery. Currently to repair damaged or non-existent cartilage in the ear, an operation is usually carried out when the patient is a child. Cartilage is extracted from the patient's ribs and painstakingly crafted into the form of an ear, before being grafted back onto the individual. Whilst this method of reconstruction achieves good results, it also has some unpleasant side effects. The patient is left with a permanent defect around the area from where the cells were harvested, as the cartilage between the ribs does not regenerate. Since any operation to replace the cartilage in the ear is for cosmetic purposes only, curing one defect by creating another (albeit in a less obvious place) is not an optimal solution. The cartilage cells used in the new technique are engineered from mesenchymal stem cells, extracted from the child's abdominal adipose tissue (fat). The benefit of this new system is that unlike … Continue reading →

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Ears and noses could be grown in lab

Posted: Published on March 4th, 2014

Then they fashion the shape of a nose or an ear by hand, before placing this 'scaffold under the skin of a patient. However, using the new technique, doctors would simply be able to 'grow a new ear or nose from scratch that would ultimately be biologically indistinguishable from the real thing. To achieve the breakthrough, researchers took stem cells from a childs abdominal fat and then combined them with a polymer 'nano-scaffold almost a microscopic netting. They then managed to manipulate this composite in a laboratory so that human cartilage tissue grew into the tiny holes within the polymer. The technique could now be used to help treat a number of conditions. For patients with 'microtia for example, the stem cells that make the cartilage tissue could be placed in a mould so that it grew into the shape of an ear. This 'cartilage ear frame would then be inserted under a flap of skin on a patients head which would mould around the shape. When a biodegradable polymer scaffold is used, it would dissolve over time, leaving only human cartilage present. Although it would not help with other functions, such as hearing, the ear would be biologically indistinguishable … Continue reading →

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Horses set to gain health benefits from stem cell advance

Posted: Published on March 4th, 2014

12 hours ago Horses suffering from neurological conditions similar to those that affect humans could be helped by a breakthrough from stem cell scientists. Researchers who are the first to create working nerve cells from horse stem cells say the advance may pave the way for cell therapies that target conditions similar to motor neurone disease. The research could also benefit horses affected by grass sickness, a neurological condition that affects around 600 horses a year in the UK. Little is known about the disease, which causes nerve damage throughout the body. It is untreatable and animals with the most severe form usually die or have to be put down. The advance by the University of Edinburgh's Roslin Institute will provide a powerful tool for those studying horse diseases. It will also help scientists to test new drugs and treatments. The researchers took skin cells from a young horse and turned them into stem cells using a technique that was originally developed for human cells. The reprogrammed cells are pluripotent, which means they can be induced to become any type of cell in the body. The team used them to create nerve cells in the laboratory and tested whether they … Continue reading →

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Dr. Doreen Granpeesheh Testifies at Informational Hearing Convened by Senate Pro Tempore Darrell Steinberg to Review …

Posted: Published on March 4th, 2014

SACRAMENTO, Calif. (PRWEB) March 04, 2014 Dr. Doreen Granpeesheh, the founder and CEO of Center for Autism and Related Disorders (CARD), testifies on behalf of Californias autism treatment providers before the California Senate Select Committee on Autism & Related Disorders at an informational hearing convened and led by Senate pro Tempore Darrell Steinberg to review Californias autism insurance mandate on Tuesday, March 4, 2014 at 1:30 p.m. at the State Capitol. Dr. Granpeesheh will address the increase in access to insurance-funded autism treatment and the issues that are still affecting families today. The California autism insurance mandate (SB 946) was implemented on July 1, 2012, and requires that most health plans cover applied behavior analysis (ABA) therapy for individuals with autism spectrum disorder (ASD). At the hearing, Dr. Granpeesheh will speak about the need for regional centers to be permitted and held responsible for paying the cost-sharing associated with insurance; the clarification required to ensure that health plans understand their responsibility for covering medically necessary treatment that occurs in a school setting; the inappropriate use of assessments to delay and/or deny treatment; the use of third-party administrators which deprives Californians of an adequate network of providers; and illegal caps on … Continue reading →

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New guidelines employ a team approach to autism diagnosis and care

Posted: Published on March 4th, 2014

Improving diagnosis and treatment for individuals with autism has been the focus of a growing body of research. New information from these studies led the American Academy of Child and Adolescent Psychiatry to revise key parameters for evaluating and treating autism. Researchers led by Yale Child Study Center director Dr. Fred Volkmar have published the new practice parameters in the Feb. issue of the Journal of the American Academy of Child and Adolescent Psychiatry. Early diagnosis of children with autism spectrum disorders means treatments will be introduced that lead to more positive outcomes for children, said Volkmar the Irving B. Harris Professor of Psychiatry, Pediatrics, and Psychology at the Yale School of Medicine. According to the parameters, clinicians should routinely look for symptoms of autism spectrum disorder in young children undergoing developmental assessments, and in all psychiatric evaluations. If significant symptoms are detected, clinicians should then coordinate a careful medical, psychological, and communication evaluation. These evaluations should differentiate between autism and a variety of developmental and other disorders, as well as intellectual and behavioral disabilities. Our goal was advocacy for individuals with autism and their families, and to ensure that services are coordinated across clinical care, said Volkmar. Our field … Continue reading →

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Autism Speaks receives $3 million gift from the Gordon & Llura Gund foundations

Posted: Published on March 4th, 2014

PUBLIC RELEASE DATE: 3-Mar-2014 Contact: Steffanie Marchese steffanie.marchese@autismspeaks.org 646-385-8537 Autism Speaks NEW YORK, N.Y. (March 3, 2014) Autism Speaks, the world's leading autism science and advocacy organization, today announced that The Gordon & Llura Gund Foundation and The Gordon & Llura Gund 93 Foundation have donated a combined $3 million to support Autism Speaks' Autism Ten Thousand Genomes (Aut10K) program to sequence the world's largest collection of whole genomes of individuals with autism spectrum disorder (ASD) and their family members. The generosity of the Gund Foundations' will significantly enhance the science and technology networks of Autism Speaks and its collaborators, enabling the organization to continue its discoveries in the research of genomics of ASD in ways that will have real-life medical impacts on individuals and families. Distributed over a three-year period, the Gund Foundations' gifts will contribute to the sequencing, data processing and analysis of over 3,000 genomes. An initial distribution of $1 million will fund Autism Speaks' Aut10K "Expansion Phase," which will invest in growing the sequence repository using the Autism Speaks Autism Genetic Resource Exchange (AGRE) library. "We are incredibly grateful to Gordon and Llura Gund and their foundations for their support in the next stage of Autism … Continue reading →

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New constipation treatment under study for Parkinson's patients

Posted: Published on March 4th, 2014

PUBLIC RELEASE DATE: 3-Mar-2014 Contact: Toni Baker tbaker@gru.edu 706-721-4421 Medical College of Georgia at Georgia Regents University Augusta, Ga. Georgia Regents Medical Center is among about a dozen centers nationally exploring the potential of a new drug that may offer relief to people with Parkinsons who have failed standard approaches to treating constipation. Constipation in Parkinsons is very prevalent, said Dr. John C. Morgan, neurologist at the Medical College of Georgia at Georgia Regents University and Director of the National Parkinsons Foundation Center of Excellence at Georgia Regents Medical Center. In fact, its one of a handful of related problems, like an impaired sense of smell, that can actually precede a Parkinsons diagnosis by years then remain a factor as more classic symptoms, such as tremors and stiffness, progress, Morgan said. Additionally, constipation can be a side effect of the myriad of medications patients may take for Parkinsons. The new study is sponsored by Rhythm, a Boston-based biotech company exploring RM-131s potential in a variety of gastrointestinal problems. The Michael J. Fox Foundation for Parkinsons Research provided Rhythm major funding for the trial of the drug for constipation in Parkinsons. Study participants will give themselves a daily injection of an … Continue reading →

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Dayton Childrens Hospital Names Gogi Kumar, MD, as Medical Director of Child Neurology

Posted: Published on March 4th, 2014

Dayton, Ohio (PRWEB) March 04, 2014 Dayton Childrens Hospital has named Gogi Kumar, MD, medical director for child neurology. Dr. Kumar has served as interim medical director for child neurology since 2013 and has been a child neurologist at Dayton Childrens since 2005. She is also an assistant professor of pediatrics at Wright State University Boonshoft School of Medicine. Dr. Kumar completed her pediatric residency at the Brooklyn Hospital Center in New York. She also completed a residency in child neurology at New York's Schneider's Childrens Hospital. Dr. Kumar is board certified by the American Board of Psychiatry and Neurology with special qualifications in child neurology. With her leadership, and the hard work and support of her colleagues, great things have been accomplished over the last several months in the neurology department, says Adam Mezoff, MD, vice president and chief medical officer at Dayton Childrens. I am confident going forward that Dr. Kumar is the right leader for our neurology team at Dayton Childrens. The department of child neurology at Dayton Childrens is committed to providing the highest quality care for infants to adolescents with a variety of neurological disorders including Tourette syndrome, cerebral palsy, neurocutaneous diseases, headache and seizure … Continue reading →

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PTSD & Traumatic Brain Injury Treatment Protocols | Personalized Medicine – Video

Posted: Published on March 4th, 2014

PTSD Traumatic Brain Injury Treatment Protocols | Personalized Medicine PTSD Traumatic Brain Injury Treatment Protocols | Personalized Medicine The Institute of Nutritional Medicine Cardiovascular Research has cutting-edge re... By: Russ Scala … Continue reading →

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Exposure to bomb blasts may cause brain injury in vets — without symptoms

Posted: Published on March 4th, 2014

In conflict zones such as Afghanistan and Iraq, military personnel are often exposed to intense explosive blasts, which can lead to symptoms of traumatic brain injury (TBI) and eventually long-term brain damage. Now, new research has revealed that veterans exposed to these types of blasts are still at risk of damage in their brains white matter even when symptoms do not present. The findings, published in the Journal of Head Trauma Rehabilitation, suggest that the absence of a TBI diagnosis does not necessarily erase a veterans risk of brain damage from blast exposure. According to senior author Dr. Rajendra Morey, very little is known about how explosive forces from bombs, grenades and other military devices impact the brain, but he described them as extremely high-pressure events. From what the military guys tell me, its a huge pressure wave, and it happens very suddenly, Morey, an associate professor of psychiatry and behavioral sciences at Duke University School of Medicine, told FoxNews.com. It kind of stuns you and could confuse you depending on how strong it is. It can knock you off your feet; throw you against a wall or vehicle. The guys describe being bell rung, where you were stunned to … Continue reading →

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