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Tackling Huntington’s disease with stem cell therapy in mice

Posted: Published on November 30th, 2013

The neurodegenerative disorder Huntingtons disease (HD) is characterised by diminished muscle coordination, cognitive impairment and behavioural changes. It is a genetic disorder caused by the expansion of a CAG trinucleotide repeat in the gene encoding the huntingtin protein. This results in the degeneration of nerve cells, starting with those in the striatum of the brain. At present there is no treatment for this disease, nor any means to slow down its progression. Current therapies therefore focus on managing symptoms. Research is underway to determine whether stem cell therapies could reduce the neuropathological deficits brought on by HD and in doing so slow disease progression. A recent study published in Stem Cell Research & Therapy by Gary Dunbar from Central Michigan University, USA and colleagues, probes the potential of mesenchymal stem cells in treating a mouse model of HD. Immunohistochemical analysis of low passage (left) and high passage (right) umbilical cord mesenchymal stem cells (blue) transplanted into the striata of R6/2 mice. Stained for NeuN (red) and GFAP (green). Image source: Fink et al, Stem Cell Research & Therapy, 2013, 4:130 Dunbar and colleagues used the R6/2 mouse model of HD to test the efficacy of umbilical cord-derived mesenchymal stem cells … Continue reading →

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Bone Marrow/Stem Cell Transplant – Video

Posted: Published on November 29th, 2013

Bone Marrow/Stem Cell Transplant The donation and infusion process for a stem cell bone marrow transplant. http://clikhere.co/VT3YlqiW. By: David Cranston … Continue reading →

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Stem Cell Transplantation for Cancer Treatment | CTCA

Posted: Published on November 29th, 2013

Stem cell transplantation Our Hematology Oncology Department provides advanced medical therapies for patients with various types and stages of hematologic disease, including leukemia, multiple myeloma, non-Hodgkin lymphomaand Hodgkin lymphoma. Some hematologic cancer patients undergo a Hematopoietic Progenitor Cell Transplantation (commonly referred to as a stem cell transplant). A stem cell transplant can be used to infuse healthy stem cells into the body to stimulate new bone marrow growth, suppress the disease, and reduce the possibility of a relapse. Stem cells can be found in the bone marrow, circulating blood (peripheral blood stem cells), and umbilical cord blood. Our doctors perform two main types of stem cell transplants: Before a stem cell transplant, you'll undergo a conditioning regime, which involves intensive treatment to destroy as many cancer cells as possible. You may receive high doses of chemotherapy and, in some cases, radiation therapy. Once this preparative regime is complete, you're ready to undergo the transplant. Much like a blood transfusion, youll receive the stem cells intravenously. The procedure takes about an hour. After entering the bloodstream, the stem cells travel to the bone marrow and start to make new blood cells in a process known as engraftment. In the months following … Continue reading →

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Stem Cell Treatment and Stem Cell Therapy | Vista Stem Cell

Posted: Published on November 29th, 2013

Stem Cell Treatment at Your Fingertips Stem cell therapy has come a long way over the last ten years, despite repeated interventions by some western governments to restrict its research. One place which has not suffered from these setbacks is China. At our facilities in Beijing, we have been administering treatments using fetal stem cells for nearly ten years with ever improving results. Our sophisticated stem cell treatment techniques and experience ensure patients receive the highest quality therapy in the world and an alternative to existing treatments that they cannot find in their own country. We use the strictest protocols to ensure that all our stem cells are disease-free and healthy. Most of our doctors were educated in the West and have a strong understanding of the demands of western patients. We believe people should not have to put up with their illness when an alternative already exists. Our mission is to improve the quality of life of all our patients and enable you to gain control over your life. View our Current Treatments section to find out more about the stem cell treatment and therapy we can provide you with. See original here: Stem Cell Treatment and Stem Cell … Continue reading →

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Phoenix Stem Clinic at Arizona Pain Specialists Now Offering …

Posted: Published on November 29th, 2013

Phoenix, Arizona (PRWEB) November 25, 2013 The top Phoenix stem cell treatment clinic, Arizona Pain Stem Cell Institute, is now offering regenerative medicine treatments for knee arthritis and cartilage defects. These stem cell injection and PRP therapy treatments may help patients avoid the need for surgery and are administered by Board Certified Phoenix pain management doctors. For more information and scheduling, call (602) 507-6550. Over the past few years, there has been rising interest in regenerative medicine which may help alter the course of one's arthritis, as opposed to simply masking pain like a "band aid". Treatments with stem cells and platelet rich plasma therapy have the potential to do just that, by alleviating pain and re-growing deficient cartilage. Small published studies have shown promising results for the stem cell treatments, which include using amniotic derived, stem cell rich material for the injections. Arizona Pain Stem Cell Institute also uses bone marrow derived and fat derived stem cell injections, which harvest the stem cell substance from the patient. The procedures are low risk, outpatient and performed by Board Certified pain doctors. The additional treatment is platelet rich plasma therapy, known as PRP therapy for short. The treatment involves a simple … Continue reading →

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The First Embryonic Stem Cell Trial

Posted: Published on November 29th, 2013

Six weeks before the hoopla over President Barack Obama's executive order lifting restrictions on embryonic-stem-cell research, Hans Keirstead, a scientist at the University of California, Irvine, was already sipping champagne. In 2005 Keirstead had published a study showing that a therapy derived from human embryonic stem cells could make partially paralyzed rats walk. Now he'd gotten word that the FDA had cleared the way for Geron, a small biotech company in California, to launch the first clinical trial of the treatment in human beings with spinal-cord injuries. It was incredible news,not just for Keirstead, who'd been wanting to invent a therapy for brain and spinal-cord disorders since he was 11 years old, but for scientists who believe human embryonic stem cells can teach them about complex diseases and potentially lead to cures. Keirstead, 41, and his team of scientists hailed the news over a case of chilled Veuve Clicquot. "We put the last bottle down about six hours later," Keirstead says. "It was just a really fun time." Opinions about the moral status of an embryo won't change with presidential decrees or FDA decisions, so you can bet that the debate over embryonic-stem-cell research is far from over. But no … Continue reading →

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What Are the Treatments for Spinal Cord Injury? | eHow

Posted: Published on November 29th, 2013

mom section Living Well Family & Relationships Education & Activities Parenting eHow Health Family Health General Family Health What Are the Treatments for Spinal Cord Injury? Nicki Howell Nicki Howell started her professional writing career in 2002, specializing in areas such as health, fitness and personal finance. She has been published at health care websites, such as HealthTree, and is a ghostwriter for a variety of small health care organizations. She earned a Bachelor of Science in business administration from Portland State University. According to the Mayo Clinic, spinal cord injuries involve much of the body. The central nervous system is made up of the brain and the spinal cord, and controls the majority of body functions. The spinal cord runs from the brain to the waist, and carries messages from the brain to the rest of the body. The majority of spinal cord injuries are caused by car accidents, falls or sport injuries. The prognosis of recovery depends on the extent of the damage. But many treatments are available to minimize spinal cord damage and work toward gaining back body functions. According to the National Institute of Neurological Disorders, in clinical trials, people who were given the medication Methylprednisolone … Continue reading →

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New treatment can improve walking for people with spinal cord …

Posted: Published on November 29th, 2013

A new study has given some spinal injured patients something to be extremely thankful for this Thanksgiving. A new treatment improved their walking ability by more than 250%. The results were published online on November 27 in online issue of Neurology, the medical journal of the American Academy of Neurology by researchers at Emory University, Georgia Institute of Technology and Shepherd Center in Atlanta, the Rehabilitation Institute of Chicago, and the University of Wisconsin, Madison. Study author Randy D. Trumbower, PT, PhD explained, About 59% of all spinal injuries are incomplete, leaving pathways that could allow the spinal cord to change in a way that allows people to walk again. Unfortunately, usually a person affected by this type of spinal injury seldom recovers the ability to walk normally. Our research proposes a promising new way for the spinal cord to make the connections needed to walk better. The study group comprised 19 individuals who had suffered spinal cord injuries located between levels C2 and T12 (the area from the neck to the lower chest). The subjects had no shortening of their joints and were able to move their ankles, knees, and hips to some degree. All were able to walk … Continue reading →

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Cerebral Palsy Causes, Symptoms, Treatment – Cerebral Palsy …

Posted: Published on November 29th, 2013

Cerebral Palsy (cont.) Medical Editor: Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology. There is no cure for cerebral palsy. With early and ongoing treatment, however, the disabilities associated with cerebral palsy can be reduced. Many different therapies are available, most under the supervision of a medical specialist or other allied professional. Not all of these therapies are right for every person with cerebral palsy. The therapy regimen for a specific individual with cerebral palsy should be tailored to meet the needs of that individual. A treatment may work for one child but not for another. The parents and the child's care team work together to choose only those treatments that offer some benefit to the child. What symptoms did your child experience with cerebral palsy? View 8 Comments Share Your Story Read the rest here: Cerebral Palsy Causes, Symptoms, Treatment - Cerebral Palsy ... … Continue reading →

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www.CLINICell.com "MENISCUS TEAR alternative with PRP and Stem Cell Therapy" – Video

Posted: Published on November 29th, 2013

http://www.CLINICell.com "MENISCUS TEAR alternative with PRP and Stem Cell Therapy" http://www.CLINICell.com offers the latest alternative treatments with PRP and Stem Cell Therapy for an MENISCUS Tear. Platelet Rich Plasma and Stem Cell treatments can be used as an alternative... By: ClinicellTech … Continue reading →

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