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Youthful stem cells from bone can heal the heart, Temple scientists report

Posted: Published on September 5th, 2013

Public release date: 4-Sep-2013 [ | E-mail | Share ] Contact: Jeremy Walter Jeremy.Walter@tuhs.temple.edu 215-707-7882 Temple University Health System (Philadelphia, PA) - Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University School of Medicine's Cardiovascular Research Center (CVRC) recently found hope in an unlikely source stem cells in cortical, or compact, bone. In a new study, they show that when it comes to the regeneration of heart tissue, these novel bone-derived cells do a better job than the heart's own stem cells. According to the study's senior investigator, Steven R. Houser, Ph.D., FAHA, Chairperson of Temple's Department of Physiology and Director of the CVRC, it is early days for cortical bone-derived stem cells (CBSCs). Nonetheless, his team's findings, featured on the cover of the August 16th issue of Circulation Research, have considerable implications for stem cell therapy for the heart. A major challenge in the treatment of heart attack is early intervention, which is key to reducing the chances for long-term complications, such as heart failure. When it comes to stem cells, Houser … Continue reading

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'Youthful' stem cells from bone can regenerate heart tissue

Posted: Published on September 5th, 2013

Washington, Sept. 05 (ANI): Researchers have found that stem cells in cortical, or compact, bone do a better job when it comes to the regeneration of heart tissue than the heart's own stem cells. The findings by senior investigator, Steven R. Houser, at Temple University School of Medicine's Cardiovascular Research Center (CVRC), have considerable implications for stem cell therapy for the heart. Stem cells are youthful by degrees, and cortical bone-derived stem cells (CBSCs) are considered some of the most pluripotent - like human newborns, naive and ready to become anything. But while CBSCs and similarly pluripotent stem cells retain the ability to develop into any cell type needed by the body and sometimes bring their youthful energy to the aid of mature cells - making them especially appealing for therapeutics - they also have the potential to wander off course, possibly landing themselves in unintended tissues. To figure out how CBSCs might behave in the heart in the first place, Houser's team began by collecting the cells from mouse tibias. The particular mice used had been engineered with green fluorescent protein (GFP), which meant that the CBSCs carried a green marker to allow for their later identification. The cells … Continue reading

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Youthful stem cells from bone can heal the heart

Posted: Published on September 5th, 2013

Sep. 4, 2013 Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University School of Medicine's Cardiovascular Research Center (CVRC) recently found hope in an unlikely source -- stem cells in cortical, or compact, bone. In a new study, they show that when it comes to the regeneration of heart tissue, these novel bone-derived cells do a better job than the heart's own stem cells. According to the study's senior investigator, Steven R. Houser, Ph.D., FAHA, Chairperson of Temple's Department of Physiology and Director of the CVRC, it is early days for cortical bone-derived stem cells (CBSCs). Nonetheless, his team's findings, featured on the cover of the August 16th issue of Circulation Research, have considerable implications for stem cell therapy for the heart. A major challenge in the treatment of heart attack is early intervention, which is key to reducing the chances for long-term complications, such as heart failure. When it comes to stem cells, Houser said, "The strategy is to inject the cells right after [a heart attack]." Currently, though, that approach works … Continue reading

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Advanced Care Veterinary Services Proves Stem Cell Therapy May Be the Best Weapon in Fighting Pet Pain Due to Arthritis

Posted: Published on September 5th, 2013

Lewisville, TX (PRWEB) September 05, 2013 Douglas P. Stramel, DVM, CVPP, CVMA owner of Lewisville based Advanced Care Veterinary Services and a certified Pain Practitioner and Veterinary Medical Acupuncturist has been a firm believer in stem cell therapy for over six years and continues to prove its effectiveness in relieving his patients from the chronic suffering that osteoarthritis can create. A recent patient, Jake, suffered from pain caused by chronic osteoarthritis in both hips. At the young age of seven months he had special surgery on both hips, but unfortunately by seven years old this Catahoula dog was showing severe suffering and lameness. He had problems getting up from a lying position, decreased activity, and was taking a long regimen of anti-inflammatory and pain medications to manage his discomfort. Jakes range of motion in his back legs was very limited and when asked to move he would whimper in pain. Jakes owners had become increasingly concerned, Jake wants to stay outside, hes less interactive with the family, limps while taking walks, and doesnt want to play ball. Previously these activities were Jakes favorite ways to pass time with his family. The pain had become so serious that Jake even hesitated … Continue reading

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Bone Marrow Mesenchymal Stem Cells Injection – Video

Posted: Published on September 4th, 2013

Bone Marrow Mesenchymal Stem Cells Injection Dr Christopher Vertullo demonstrates arthroscopic view of bone marrow derived mesenchymal stem cell delivery after marrow stimulation opening wedge high ti... By: Dr Christopher Vertullo: Knee.Surgeon.net … Continue reading

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New recombinant antibody can isolate stem cells from umbilical cord blood

Posted: Published on September 4th, 2013

Public release date: 3-Sep-2013 [ | E-mail | Share ] Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News New Rochelle, NY, September 3, 2013A new recombinant antibody can detect and isolate mesenchymal stem cells (MSCs), a nonembryonic source of stem cells with promising applications in tissue engineering, blood stem cell transplantation, and treatments for immune-mediated disorders. The antibody recognizes an i blood group antigen present on MSCs in umbilical cord blood, as described in a study published in BioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access website. Tia Hirvonen and coauthors from the Finnish Red Cross Blood Service, Glykos Finland Ltd., and Biova Ltd. (Helsinki), and VTT Technical Research Center of Finland (Espoo), identified a blood donor with high levels of antibody to the i blood group antigen. No antibodies recognizing this antigen are commercially available at present. In the article "Production of a Recombinant Antibody Specific for i Blood Group Antigen, a Mesenchymal Stem Cell Marker," the authors explain that the i antigen can serve as a marker to detect and isolate MSCs in umbilical cord blood (UCB). They describe the use … Continue reading

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Bismuth-carrying nanotubes show promise for CT scans

Posted: Published on September 4th, 2013

Sep. 4, 2013 Scientists at Rice University have trapped bismuth in a nanotube cage to tag stem cells for X-ray tracking. Bismuth is probably best known as the active element in a popular stomach-settling elixir and is also used in cosmetics and medical applications. Rice chemist Lon Wilson and his colleagues are inserting bismuth compounds into single-walled carbon nanotubes to make a more effective contrast agent for computed tomography (CT) scanners. Details of the work by Wilson's Rice team and collaborators at the University of Houston, St. Luke's Episcopal Hospital, and the Texas Heart Institute appear in the Journal of Materials Chemistry B. This is not the first time bismuth has been tested for CT scans, and Wilson's lab has been experimenting for years with nanotube-based contrast agents for magnetic resonance imaging (MRI) scanners. But this is the first time anyone has combined bismuth with nanotubes to image individual cells, he said. "At some point, we realized no one has ever tracked stem cells, or any other cells that we can find, by CT," Wilson said. "CT is much faster, cheaper and more convenient, and the instrumentation is much more widespread (than MRI). So we thought if we put bismuth … Continue reading

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Stem cell treatment/therapy for Alzheimer / Dementia – Video

Posted: Published on September 4th, 2013

Stem cell treatment/therapy for Alzheimer / Dementia Video sent by dementia patient, documenting her improvements following stem cell therapy. By: A1MedicalCenter … Continue reading

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A1 Stem cell treatment for Spinal Cord Injury – Video

Posted: Published on September 4th, 2013

A1 Stem cell treatment for Spinal Cord Injury Video documentation of stem cell therapy patient, who received stem cell treatments at the one of A1 Medical Centers for Spinal Cord Injury. By: A1MedicalCenter … Continue reading

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A1 Stem cell treatment for Stroke – Video

Posted: Published on September 4th, 2013

A1 Stem cell treatment for Stroke Video documentation of stem cell therapy patient, who received stem cell treatments at the one of A1 Medical Centers for Stroke. By: A1MedicalCenter … Continue reading

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