Liestal, Switzerland, September 3, 2013 - Santhera Pharmaceuticals (SIX:SANN) announced today that it reached an agreement with Takeda to license back previously granted European rights to Catena(INN:idebenone) in Duchenne Muscular Dystrophy (DMD). In a back-loaded deal, Santhera regains European commercialization rights for Catena. The drug is currently being investigated in a PhaseIII study in DMD conducted in Europe and in the USA. In 2007, Takeda Pharmaceutical Company Limited (TSE:4502, "Takeda") acquired the exclusive marketing rights in Europe and Switzerland for Catena for the treatment of DMD. Under the agreement reached today, Santhera licenses back all such previously granted rights to increase its strategic flexibility. In return, Takeda is eligible to obtain a percentage from future licensing and/or sales income generated by Santhera in DMD. In addition, Santhera has obtained the right to cross-reference Takeda`s idebenone data for regulatory use in any indication in any territory. If Santhera makes use of such cross-reference right, Takeda is eligible to obtain a percentage from future licensing and/or sales income generated by Santhera in such indications. Lastly, both companies agreed to terminate a similar agreement for Friedreich`s Ataxia signed in 2005 and Santhera`s previously disclosed contingent liability of EUR1million payable to Takeda has been … Continue reading →

MIAMI - Each year, 700,000 people suffer a stroke in the United States. Until now, the only recovery for paralysis brought on by the stroke was lengthy rehabilitation. Now, a new stem cell therapy is helping stroke patients move again. James Anderson is a triathlete and physical education teacher who was visiting Florida from Maine when suddenly, "I started to feel a little dizzy a little tingling in my right hand and ah I ended up having a stroke," he said. Anderson did not respond to clot-busting medication or blockage treatments. So, he became paralyzed on the left side of his body. Dr. Dileep R. Yavatal, a neurologist, treated him as part of a clinical trial in which some of the patients were treated with their own stem cells. While Anderson doesnt know if he was injected with his own stem cells, two months after treatment, Anderson said, "I have had more movement and strength in my legs." For the clinical trial, stem cells must be injected into the brain no later than two weeks after the stroke occurs. Anderson is now able to move around with a walker during rehab and hopes to be able to compete in a … Continue reading →

Sep. 1, 2013 Stem cell therapy used to regenerate injured tissue in the heart restores synchronous pumping, shows research published today [1 September] in The Journal of Physiology. The study proposes a novel strategy of 'biological resynchronisation' in which stem cells repair heart muscle damage to reestablish correct cardiac motion. Heart attacks limit local oxygen, which can kill areas of cardiac tissue -- called 'infarcted' areas -- and also leave scarring. This damage leads to a lack of synchrony in the heart beat motion. Current therapies use pacing devices, but these require healthy tissue for optimal outcome, meaning a third of patients do not respond well to this treatment. However, this new approach discovered by a team at Mayo Clinic in Rochester, Minnesota, USA overcomes this limitation as stem cells actually form functional cardiac tissue and reconstruct heart muscle. Professor Andre Terzic, who led the study, explains the importance of this potential new therapy: "Heart chambers must beat in synchrony to ensure proper pumping performance. Damage to the heart can generate inconsistent wall motion, leading to life-threatening organ failure. "The heart is vulnerable to injury due to a limited capacity for self-repair. Current therapies are unable to repair damaged cardiac … Continue reading →

Working At The Option Institute™ - Teamwork and Support http://www.option.org At The Option Institute and the Autism Treatment Center of America™ we offer you a work experience where we help you scale the heights of your personal professional... By: optionvideodept … Continue reading →