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Lilly stops mid-stage Alzheimer's drug study

Posted: Published on June 14th, 2013

NEW YORK (AP) -- Eli Lilly and Co. said Thursday that it stopped a mid-stage clinical trial of an experimental Alzheimer's disease drug because of potential side effects on patients' livers. The company stopped testing LY2886721 because of abnormal results in liver biochemical tests. Lilly says the results were found as part of routine monitoring and it will continue to monitor all patients. The Indianapolis company will evaluate data from the trial before deciding on the next steps for the drug. Lilly says it may continue development of similar drugs. Lilly will take a charge related to stopping the trial, but it won't affect its full-year guidance. About 35 million people worldwide have dementia. Alzheimer's is the most common type and there are around 5 million patients in the U.S. Approved drugs like Aricept and Namenda temporarily ease symptoms, but there is no cure. The company is also running late-stage studies on the drug solanezumab as a treatment for Alzheimer's disease. Solanezumab targets beta-amyloid, the sticky plaque that gums up the brains of patients with the disease. In August 2010 Lilly ended a late-stage trial of the Alzheimer's drug semagacestat, which was more like LY2886721 than solanezumab. Both drugs target … Continue reading

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King County's Mental Illness and Drug Dependency Programs – Video

Posted: Published on June 14th, 2013

King County's Mental Illness and Drug Dependency Programs See how King County is helping people struggling with mental illness and drug addictions stabilize and stay out of jail. By: KingCountyTV … Continue reading

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Tom Sizemore faces his drugs demons

Posted: Published on June 14th, 2013

Tom Sizemore faces his drugs demons 7:30pm Friday 14th June 2013 in National Entertainment News Press Association 2013 Tom Sizemore has revealed he was prompted to seek help for his drug addiction problems when he looked in the mirror and was terrified by what he saw. The 51-year-old star of Saving Private Ryan and Hawaii Five-0 has struggled through a long battle with heroin and crystal meth that devastated his movie career, left him homeless, sent him to jail and even led to a failed suicide attempt. Talking about his memoir, By Some Miracle I Made It Out Of There, Sizemore described his moment of clarity. He said it came after smoking a substantial amount of crystal meth. He admitted to building up such a tolerance that the drug was ineffective. Disappointed, he looked in the mirror and finally saw the things that scared him. "I looked like I was 100 years old. I had no relationship with my kids; I had no work to speak off. I was living in squat ... I just started to cry," Sizemore said. He decided to call his old friend Bob Forrest from Celebrity Rehab and asked him and Dr Drew Pinsky for … Continue reading

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Tom Sizemore honest about long-lasting drug battle

Posted: Published on June 14th, 2013

NEW YORK (AP) The road to recovery has been long and harrowing for Tom Sizemore, but now the actor feels he's finally back on track. He's got a slew of movies coming out, had a recurring role on "Hawaii Five-0" and has released a new memoir. Still, he feels the residual effects of his downward spiral from years of substance dependency. His bouts with a laundry list of drugs devastated his movie career, left him homeless, sent him to jail and even led to a failed suicide attempt. The prolonged abuse and subsequent rehab stints left a trail of disappointment and heartache. With acclaimed performances in movies like "Saving Private Ryan" and "Black Hawk Down," Sizemore faded into oblivion, trading his work in front of the camera for the haze of heroin and crystal meth. Recently, the 51-year old actor talked about getting his life back on track and what it took to write his memoir, "By Some Miracle I Made It Out of There." It's a no-holds barred portrayal of the actor's struggle. While apprehensive at times,Sizemore was candid about his problem, and described his moment of clarity. He says it came after smoking a substantial amount of crystal … Continue reading

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Study Says HIV Drug Tenofovir Also Helps Prevent Contraction Of The Virus

Posted: Published on June 14th, 2013

June 13, 2013 Brett Smith for redOrbit.com Your Universe Online New research from the Centers for Disease Control and Prevention suggests that a daily pill can prevent the contraction of HIV for intravenous drug users. The four-year study, which was published in The Lancet, boosts the argument of those advocating a preventative strategy called pre-exposure prophylaxis, or PrEP. This is a significant step forward for HIV prevention, Jonathan Mermin, a CDC spokesman who was not directly involved in the study, told the AFP. We now know that PrEP can work for all populations at increased risk for HIV. Injection drug use accounts for a substantial portion of the HIV epidemic around the world, and we are hopeful that PrEP can play a role in reducing the continued toll, he added. The study included 2,400 intravenous drug users in Thailand who were attending drug treatment clinics and did not test positive for HIV when the study began. The volunteers were divided into two groups: one was given a daily dose of the HIV drug tenofovir, while the other was given a placebo. Both groups were offered monthly testing for HIV, condoms and treatments for their drug dependency. To encourage volunteers in … Continue reading

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Trig the merchant episode 3: a khajiit's drugs – Video

Posted: Published on June 14th, 2013

Trig the merchant episode 3: a khajiit's drugs We find a khajiit who sells drugs. By: Akatosh Cat … Continue reading

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This is ur brain on drugs – Video

Posted: Published on June 14th, 2013

This is ur brain on drugs Funny as fuck. By: bre Dean … Continue reading

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COPPER Inside the New Season: "Sex, Drugs

Posted: Published on June 14th, 2013

COPPER Inside the New Season: "Sex, Drugs Violence" - SUN JUNE 23 BBC AMERICA Get an exclusive, behind-the-scenes look at the new season of COPPER - with exclusive interviews with stars TOM WESTON JONES (Detective Kevin Corcoran) and D... By: BBCAmericaTV … Continue reading

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Scott Storch: I'm Fiending Music Now, Not Drugs – Video

Posted: Published on June 14th, 2013

Scott Storch: I'm Fiending Music Now, Not Drugs http://www.vladtv.com/ - Super producer Scott Storch discusses his recent stint in rehab, and explains how it changed him for the better. He also reveals how... By: djvlad … Continue reading

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Black Man with No Drugs in His System Arrested for DUI – Video

Posted: Published on June 14th, 2013

Black Man with No Drugs in His System Arrested for DUI Arizona man files lawsuit after being arrested for DUI while having a 0.00 blood alcohol level. By: Dprippa … Continue reading

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