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Toddler Gets Windpipe Transplant Made From Her Stem Cells

Posted: Published on May 1st, 2013

Jim Carlson / OSF Saint Francis Medical Center / handout / AP Darryl Warren and Lee Young-mi visit their 2-year-old daughter, Hannah Warren, in a post-op room at the Children's Hospital of Illinois in Peoria after having received a new windpipe in a landmark transplant operation on April 9, 2013. Hannah Warren was born without a trachea but now has one made from plastic fibers and a stew of her own stem cells. The 2-year-old Korean Canadian has spent every day of her life in intensive care, kept alive by a tube that substituted for the windpipe that was supposed to connect her mouth to her lungs. But nearly a month after her transplant, the toddler is mostly breathing on her own and is responding to doctors and nurses. The surgery, pioneered by Dr. Paolo Macchiarini, director of the Advanced Center for Translational Regenerative Medicine at the Karolinska Institute in Stockholm, was only the sixth performed in the world, and Hannah was the youngest patient and first to receive the transplant in the U.S. The procedure was approved by theFDAas anexperimental operation for patients with very little hope of survival; being born without a trachea is fatal in 99% of … Continue reading

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2-year-old girl gets windpipe made from stem cells

Posted: Published on May 1st, 2013

CHICAGO (AP) -- A 2-year-old girl born without a windpipe now has a new one grown from her own stem cells, the youngest patient in the world to benefit from the experimental treatment. Hannah Warren has been unable to breathe, eat, drink or swallow on her own since she was born in South Korea in 2010. Until the operation at a central Illinois hospital, she had spent her entire life in a hospital in Seoul. Doctors there told her parents there was no hope and they expected her to die. The stem cells came from Hannah's bone marrow, extracted with a special needle inserted into her hip bone. They were seeded in a lab onto a plastic scaffold, where it took less than a week for them to multiply and create a new windpipe. About the size of a 3-inch tube of penne pasta, it was implanted April 9 in a nine-hour procedure. Early signs indicate the windpipe is working, Hannah's doctors announced Tuesday, although she is still on a ventilator. They believe she will eventually be able to live at home and lead a normal life. "We feel like she's reborn," said Hannah's father, Darryl Warren. "They hope that … Continue reading

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Girl gets stem cell windpipe in historic operation

Posted: Published on May 1st, 2013

A two-year-old girl born without a windpipe now has a new one grown from her own stem cells, making her the youngest patient in the world to benefit from the experimental treatment. Hannah Warren has been unable to breathe, eat, drink or swallow on her own since she was born in South Korea in 2010. Until the operation at a U.S. hospital, she had spent her entire life in a hospital in Seoul. Doctors there told her parents there was no hope and they expected her to die. The stem cells came from Hannah's bone marrow, extracted with a special needle inserted into her hip bone. They were seeded in a lab onto a plastic scaffold, where it took less than a week for them to multiply and create a new windpipe. The windpipe was implanted April 9 in a nine-hour procedure. Early signs indicate the windpipe is working, Hannah's doctors announced Tuesday, although she is still on a ventilator. They believe she will eventually be able to live at home and lead a normal life. "We feel like she's reborn," said Hannah's father, Darryl Warren. "They hope that she can do everything that a normal child can do but … Continue reading

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ViaCord® to Advance Cord Blood Stem Cell Therapy Research through Collaboration with the Center for International …

Posted: Published on May 1st, 2013

WALTHAM, Mass.--(BUSINESS WIRE)-- ViaCord, PerkinElmers family cord blood and tissue preservation business, is collaborating with the Center for International Blood and Marrow Transplant Research (CIBMTR) to collect, maintain and publish research from ViaCords cord blood stem cell transplants. This collaboration will expand knowledge of cord blood-derived stem cell applications throughout the medical and research community. To date, CIBMTRs large network of transplant centers has resulted in the development of a clinical database of more than 30,000 cord blood transplant recipients for clinical decision-making, use in studies, and other research purposes with the goal of making a profound impact on the survival of cord blood transplant patients around the world. CIBMTR will work directly with ViaCord to collect and analyze data to better understand the quality and any outcome metrics of ViaCords released cord blood stem cell units as well as how the units are being used. Collaborating with CIBMTR, which has established the industry standard for collecting data around hematopoietic cellular therapy and regenerative medicine, allows us to simultaneously gain insights into the effectiveness of the cord blood stem cell units we have released for use as well as outcomes from their clinical application, said Morey Kraus, Chief Scientific Officer, … Continue reading

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Stem cells grow new windpipe for 2-year-old girl facing death

Posted: Published on May 1st, 2013

Experimental stem-cell treatment has been credited with saving the life of a 2-year-old girl who was born without a windpipe. The Associated Press reported that the treatment involved extracting cells from the girls own hip bone marrow. The cells were then seeded on a plastic base, and left for a week to multiply and grow. They grew into a windpipe, which was subsequently implanted on the girl, Hannah Warren, in a nine-hour surgery on April 9, AP reported. Until her operation, the girl who was born in South Korea in 2010 had not been able to breathe or eat without medical assistance. She had spent her entire life in a Seoul hospital, awaiting death until being transported to the United States for the experimental treatment. Early prognosis is positive. Doctors said Tuesday she will likely be able to lead a normal life, AP reported. We feel like shes reborn, said her father, Darryl Warren, in the AP report. They hope that she can do everything that a normal child can do, but its going to take time. This is a brand new road that all of us are on. This is her only chance, but shes got a fantastic one … Continue reading

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Stem-cell windpipe gives 2-year-old chance for normal life

Posted: Published on May 1st, 2013

A 2-year-old girl born without a windpipe now has a new one grown from her own stem cells, the youngest patient in the world to benefit from the experimental treatment. Hannah Warren has been unable to breathe, eat, drink or swallow on her own since she was born in South Korea in 2010. Until the operation at a central Illinois hospital, she had spent her entire life in a hospital in Seoul. Doctors there told her parents there was no hope and they expected her to die. The stem cells came from Hannah's bone marrow, extracted with a special needle inserted into her hip bone. They were seeded in a lab onto a plastic scaffold, where it took less than a week for them to multiply and create a new windpipe. About the size of a 3-inch tube of penne pasta, it was implanted April 9 in a nine-hour procedure. Early signs indicate the windpipe is working, Hannah's doctors announced Tuesday, although she is still on a ventilator. They believe she will eventually be able to live at home and lead a normal life. "We feel like she's reborn," said Hannah's father, Darryl Warren. "They hope that she can do … Continue reading

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Save The Cord Foundation, a Global Leader in Cord Blood Advocacy, Announces its Expansion of Educational Information …

Posted: Published on April 30th, 2013

Tucson, Arizona (PRWEB) April 30, 2013 Save the Cord Foundation, a trusted non commercial resource for education and awareness of umbilical cord blood and cord tissue preservation, today announced it will expand its web information base to include the new industry-changing technologies that allow for the collection and storage of Dental Pulp Stem Cells, a type of multi-potent adult stem cell found in the pulp chamber of teeth, that show a strong potential to treat a variety of diseases. Save the Cord Foundation is a 501c3 nonprofit (tax-exempt) foundation created to advance cord blood and cord tissue awareness, education, research and legislation. The foundations mission is to provide FREE, unbiased, factual information to expectant parents and the public concerning the medical value and life-saving benefits of saving umbilical cord blood and the future potential for using cord tissue as a regenerative medical resource. The foundation educates expectant parents about the medical value of their newborns cord blood, so they can make their own informed decision about the options for saving it; public donation, private banking or donation to research. Save the Cord Foundations vision is to make saving cord blood the standard of care for all newborns and cord blood … Continue reading

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Stemedica Issued U.S. Patent For Ectodermal Stem Cells

Posted: Published on April 30th, 2013

San Diego, CA (PRWEB) April 30, 2013 Stemedica Cell Technologies, Inc., a leading manufacturer of adult allogeneic stem cells and stem cell factors announced that the Company has been issued keystone Patent No. 8,420,394 titled Culturing Ectodermal Cells Under Reduced Oxygen Tension by the United States Patent and Trademark Office (USPTO). This patent broadly covers Stemedicas proprietary manufacturing process for enhancing the proliferation and differentiation potential of ectodermal cells of any origin. The ectodermal layer gives rise to the cells of the skin and nervous system. The patented process provides Stemedica exclusivity for expanding and manufacturing ischemia tolerant ectodermal cells under reduced oxygen tension. Nikolai Tankovich, MD, PhD, FASLMS, President and Chief Medical Officer of Stemedica noted, We are pleased that the USPTO recognizes the uniqueness of the technology and processes to manufacture ectodermal cell of any origin. This includes, but is not limited to: allogeneic and autologous adult, embryonic, parthenogenic and iPS sources of stem cells. When compared to stem cells expanded in normal oxygen, Stemedica cells exhibit superior migratory and engraftment properties, enhanced gap junction formation and a unique gene profile. These critical cell characteristics are the direct result of Stemedicas proprietary technology and expansion methodology. Alex Kharazi, … Continue reading

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MDA Shamrocks Program Raises More Than $23.3 Million – And Counting – For Children And Adults Fighting Muscle Disease

Posted: Published on April 30th, 2013

TUCSON, Ariz., April 30, 2013 /PRNewswire-USNewswire/ -- With the help of strong and dedicated retail partners and their caring customers, the Muscular Dystrophy Association's vital research and health care services programs will continue to benefit MDA families across the nation, thanks to the $23.3 million raised in its annual MDA Shamrocks fundraising program this season. (Logo: http://photos.prnewswire.com/prnh/20120424/DC93207LOGO) The campaign, which is centered on St. Patrick's Day, continues its record-breaking fundraising success, with total numbers still to be finalized. "Our Shamrocks program allows our retail partners and their generous customers to play a key role in elevating the Association's mission to offer help and hope to the families we serve in every community," said MDA President and CEO Steven M. Derks. "Every Shamrock purchased can have a life-changing effect by helping to fund the most promising research into lifesaving treatments and cures for muscle disease. We can't thank our partners and the American public enough for their continued support." Monies raised also provide MDA families with essential health care service programs, such as MDA clinics where individuals can be seen by a multidisciplinary team specializing in neuromuscular diseases. MDA clinics are at the forefront of research and treatment, and often serve … Continue reading

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Parent Project Muscular Dystrophy Collaborates with Siren Interactive on Mobile App for Duchenne Community

Posted: Published on April 30th, 2013

HACKENSACK, N.J., April 29, 2013 /PRNewswire-USNewswire/ --Parent Project Muscular Dystrophy (PPMD), the leading nonprofit in the United States focused entirely on Duchenne muscular dystrophy (Duchenne), launched the Duchenne Central mobile app, in collaboration with Siren Interactive, a digital relationship marketing agency focused on rare disorder therapies. The app, which is available as a free download for Apple and Android devices, is an easy-to-use and on-the-go tool to locate clinical trials and clinics and view and share the latest Duchenne news. Duchenne is a fatal genetic disorder that slowly robs young men of their muscle strength. "Currently, there are no FDA-approved treatments for Duchenne; however, there are several potential therapies in development and currently in clinical trials," notes Pat Furlong, founding president and CEO of PPMD. "It's essential that patients and their families have ongoing access to information on the latest clinical trials. We're proud to bring this new resource to the Duchenne community." The app was developed with the goal of filling a need for the Duchenne community and developed with the experts at PPMD. Especially for rare disorders, enrolling enough patients in a clinical trial can be challenging. "With the explosive growth of mobile devices, people are using their … Continue reading

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