Published in the journal Science and Technology of Advanced Materials Vol. 14, p. 025003 ( http://iopscience.iop.org/1468-6996/14/2/025003), the study found that a stiff or rigid environment not only enhances the function of existing cardiomyocytes (as has previously been shown), but also promotes the generation of cardiomyocytes from embryonic stem (ES) cells. It may therefor be possible to grow new heart muscle tissue from stem cells by manipulating the stiffness of the medium they're grown in. In living organisms, a type of adult stem cells called mesenchymal stem cells (MSCs) are extremely sensitive to the elasticity of different materials, when cultured outside the body. For example, soft growing matrices that mimic brain tissue promote the differentiation of MSCs into neurons, while rigid matrices that resemble bone tissue promote the differentiation of MSCs into bone cells. In this study, the UCLA team examined the role of matrix elasticity on cardiac muscle development using mouse and human embryonic stem cells, which were grown on different substrates of a silicon-based organic polymer that varied in stiffness. The team found that rigid matrices promoted the generation of more cardiomyocytes cells from ES cells. In addition, ES-derived cardiomyocytes displayed functional maturity and synchronization of beating when cultured … Continue reading
Categories
- Aesthetic Medicine
- Aesthetic Surgery
- Ai
- ALS Treatment
- Anatomy
- Artificial General Intelligence
- Artificial Intelligence
- Artificial Super Intelligence
- Batten Disease Treatment
- BioEngineering
- BioInformatics
- Biology
- Biotechnology
- Bitcoin
- Brain Injury Treatment
- Cardiac Nursing
- Cardiac Regeneration
- Cardiac Remodeling
- Cardiac Rhythm Abnormalities
- Cardiac Surgery
- Cardiology
- Cardiomyopathies
- Cardiovascular Pharmacology
- Cell Medicine
- Cell Therapy
- Cerebral Palsy
- Cerebral Palsy Treatment
- Cheap Pharmacy
- Chemistry
- Clinical Cardiology
- Coronary Heart Diseases
- Cryptocurrency
- DNA
- Drug Dependency
- Drug Side Effects
- Drugs
- Eczema
- Elon Musk
- Embryology
- Erectile Dysfunction
- FDA Stem Cell Trials
- Femtomedicine
- Future Medicine
- Gene Medicine
- Gene Therapy
- Gene Therapy Trials
- Genetic Engineering
- Genetic Therapy
- Genetics
- Germ Line Engineering
- Heart Diseases
- HGH
- Hgh Injections
- Hormone Replacement Therapy
- Human Genetics
- Human Growth Hormone
- Human Immortality
- Hyperbaric Medicine
- Hypertension
- Hypothalamus
- Impotency
- Internet Pharmacy
- Interventional Cardiology
- IVF Treatment
- Lyme Disease
- Male Sexual Dysfunction
- Mars Colony
- Medical Business
- Medical School
- Medical Technology
- Medicine
- Mental Health
- Mesenchymal Stem Cells
- Micropenia
- Molecular Cardiology
- MS Treatment
- Muscular Dystrophy Treatment
- Myocardial Infarction
- Nanotechnology
- Online Pharmacy
- Oral Health
- Parkinson's Treatment
- Pediatric Cardiology
- Penis Enlargement
- Pet Stem Cell Therapy
- Pharmacy
- Picomedicine
- Premature Ejaculation
- Prescriptions
- Retinitis Pigmentosa
- Sermorelin
- Singularity
- Sleep
- Spacex
- Spinal Cord Injury Treatment
- Stem Cell Clinical Trials
- Stem Cell Experiments
- Stem Cell Human Trials
- Stem Cell Injections
- Stem Cell Research
- Stem Cell Transplant
- Stem Cell Treatments
- Testosterone
- Ulcerative Colitis
- Uncategorized
- Vascular Biology
- Ventricular Remodeling
- Wholesale Pharmacy
Archives