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Valley doctors inch forward with Parkinson's test

Posted: Published on January 24th, 2013

SUN CITY, Ariz. -- For Drs. Charles Adler and Thomas Beach, one of the most difficult parts of diagnosing Parkinson's disease is that they could be wrong. "There is no test, so we don't have any way of looking at making a diagnosis while someone is alive," said Adler, a neurologist with the Mayo Clinic in Scottsdale. But Adler and Beach, a senior scientist at the Banner Sun Health Research Institute, are reporting strides in developing the first diagnostic test to detect Parkinson's, a devastating and chronic neurological disorder. A study they conducted through the Mayo Clinic and Banner Health found that examining a portion of a person's saliva gland may allow doctors to diagnose the disease. They will present the study in March at the American Academy of Neurology's annual meeting. Should this lead to a diagnostic test, Adler said he is pretty confident it will be able to change the course of the disease. "Patients often undergo invasive treatment, and people who don't have Parkinson's don't respond well," Adler said. "Being able to tell people, Yes, you do have Parkinson's,' would make it much easier." Diagnosis has for years occurred through a sometimes inaccurate examination of symptoms such … Continue reading

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Growth of telehealth, Parkinson’s treatment pipeline propels Great Lakes NeuroTech into new markets

Posted: Published on January 24th, 2013

Cleveland-area patient monitoring company Great Lakes NeuroTechnologies is using the momentum its built in the clinical trials market to drive penetration of its device/software technology for assessing Parkinsons disease symptoms other markets this year. The companys FDA-cleared Kinesia technology platform is designed to give clinicians a quantitative way to assess the severity of motor-related symptoms associated with Parkinsons. To use it, patients wear a motion sensor device on their finger and perform a series of motor tests prompted by accompanying web-based software. The sensor captures linear acceleration and angular velocity data and transmits it via Bluetooth to the software, which generates reports to help patients and clinicians track symptoms over time. Company President Joe Giuffrida said the system is used primarily in three ways: By clinicians to monitor patients disease progression and how treatments affect their symptoms; by researchers to evaluate the effectiveness of drugs in clinical trials; and by neurologists to fine-tune the programming of deep brain stimulation devices after theyve been implanted. We are getting a lot of traction in the clinical trials market right now, Giuffrida said. Thats because Parkinsons is an active space for drug development, with more than 150 individual programs, most of which are … Continue reading

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Petrick shows perseverance in battle vs. Parkinson's

Posted: Published on January 24th, 2013

HILLSBORO, Ore. -- Ben Petrick is talking about a career highlight. It happened just the other morning. Petrick, the onetime Major League catcher whose bright future in baseball was erased by Parkinson's disease, was in his house, watching his 5-year-old daughter, Makena, while his soon-to-be-1-year-old, Madison, napped, and his wife, Kellie, was out teaching third graders. Petrick hadn't taken his medication, and when he's "off," things can get dicey. Petrick's walk from one end of the kitchen to the other became a dizzied stagger. The rigidity of his plagued body took over and he lost his balance. He fell to his knees and stayed in the position for a moment, collecting himself to try to get back up. Then he felt little arms around his shoulders. "Daddy, are you OK?" Makena said. "Yeah, sweetie," he said. "I'm OK." *** A look at Ben Petrick's player page doesn't reveal anything out of the ordinary, even for a guy who had become one of the top prospects in his sport by the time he debuted for the Colorado Rockies on Sept. 1, 1999, at the age of 22. It's pretty common for even a blue-chipper to never quite figure it out at … Continue reading

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Oxygen chamber can boost brain repair years after stroke or trauma

Posted: Published on January 24th, 2013

Jan. 23, 2013 Stroke, traumatic injury, and metabolic disorder are major causes of brain damage and permanent disabilities, including motor dysfunction, psychological disorders, memory loss, and more. Current therapy and rehab programs aim to help patients heal, but they often have limited success. Now Dr. Shai Efrati of Tel Aviv University's Sackler Faculty of Medicine has found a way to restore a significant amount of neurological function in brain tissue thought to be chronically damaged -- even years after initial injury. Theorizing that high levels of oxygen could reinvigorate dormant neurons, Dr. Efrati and his fellow researchers, including Prof. Eshel Ben-Jacob of TAU's School of Physics and Astronomy and the Sagol School of Neuroscience, recruited post-stroke patients for hyperbaric oxygen therapy (HBOT) -- sessions in high pressure chambers that contain oxygen-rich air -- which increases oxygen levels in the body tenfold. Analysis of brain imaging showed significantly increased neuronal activity after a two-month period of HBOT treatment compared to control periods of non-treatment, reported Dr. Efrati in PLoS ONE. Patients experienced improvements such as a reversal of paralysis, increased sensation, and renewed use of language. These changes can make a world of difference in daily life, helping patients recover their … Continue reading

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Kitware to Develop Novel Neuroimage Processing Methods for Traumatic Brain Injury

Posted: Published on January 24th, 2013

The NIH-funded project will investigate new methods for better assessing TBI. Clifton Park, NY (PRWEB) January 23, 2013 Nearly 1.7 million Americans suffer TBI annually as a result of car accidents, blunt trauma, gunshots, military combat, and other head traumas. Many who experience TBI require surgical intervention, and in some cases, require daily assistance for years post-injury. Healthcare costs associated with current TBI treatment exceed $60 billion a year; however, existing analytic assessment methods fall short of clinical need. Clinicians require informative metrics and easy-to-use image analysis tools capable of handling large, heterogeneous pathologies that cause severe brain deformations. To address these critical needs, Kitware will collaborate with Dr. Marc Niethammer at the University of North Carolina, Chapel Hill and Dr. Jack Van Horn at the University of California, Los Angeles (UCLA). The team will leverage computational methods for segmenting, registering, and interpreting images that contain large and changing pathologies to better characterize injury, quantify longitudinal changes, predict outcomes, and support patient treatment management. At Kitware, Stephen Aylward, Senior Director of Operations, North Carolina, is the Principal Investigator; he will work closely with Project Leader Danielle Pace, a Research and Development Engineer at Kitware. The team will perform multimodal brain … Continue reading

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Hyperbaric Treatment in Oxygen Chamber Brings Stroke Damaged Brains to Life

Posted: Published on January 24th, 2013

E-mail this page to a friend! Health & Medicine for Senior Citizens Hyperbaric Treatment in Oxygen Chamber Brings Stroke Damaged Brains to Life Tenfold increase in oxygen levels during HBOT treatment supplies the necessary energy for rebuilding neuronal connections and stimulating inactive neurons Jan. 23, 2013 - Stroke, traumatic injury, and metabolic disorder are major causes of brain damage and permanent disabilities, including motor dysfunction, psychological disorders, memory loss, and more. Most therapy and rehab has limited success. There is new hope from Tel Aviv University, however, where researchers say they have been able to restore a significant amount of neurological function in brain tissue thought to be chronically damaged even years after the initial damage. Now Dr. Shai Efrati of Tel Aviv University's Sackler Faculty of Medicine has found a way to restore a significant amount of neurological function in brain tissue thought to be chronically damaged even years after initial injury. Theorizing that high levels of oxygen could reinvigorate dormant neurons, Shai Efrati of Tel Aviv University's Sackler Faculty of Medicine and his fellow researchers, including Prof. Eshel Ben-Jacob of TAU's School of Physics and Astronomy and the Sagol School of Neuroscience, recruited post-stroke patients for hyperbaric oxygen … Continue reading

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New Scan May Enable Better Diagnosis, Treatment for Athletes' Brain Damage

Posted: Published on January 24th, 2013

JEFFREY BROWN: Next: how brain scans may be able to help identify serious head injuries to living and retired football players and to the rest of us. In less than two weeks, football fans will gather for the country's biggest sporting event, Super Bowl Sunday. But even as pro football is drawing strong ratings, there are growing concerns about the long-term effects of concussions and other hits to the head. Today, researchers in California and Illinois reported they can identify protein deposits in the brains of living players that could help identify those at risk of developing an injury known as CTE, chronic traumatic encephalopathy. The study done by Gary Small of UCLA and others is quite small. Five former players, all retired and between the ages of 45 and 73, were given a compound that showed a buildup of a protein known as tau in the brain. DR. GARY SMALL, UCLA: We see, here's the cortex and the deeper brain structures. JEFFREY BROWN: Dr. Small is the lead author of the new paper published in "The American Journal of Geriatric Psychiatry." GARY SMALL: This is the first time we have been able to image in living football players protein … Continue reading

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Bill would fund research for spine, brain injuries

Posted: Published on January 24th, 2013

By ECM on January 23, 2013 at 6:48 pm by T.W. Budig ECM Capitol reporter Its more than just another bill to her, explained Rep. Laurie Halverson of Eagan. Halverson is carrying legislation to create a research grant program to fund breakthrough research and treatment of spinal cord and traumatic brain injury. Gabe Roderick talks about how a spinal injury has affected his life, and of the simple bodily functions he hopes to regain some day. Rep. Laurie Halverson, DFL-Eagan, standing behind Roderick, is carrying legislation to create a grant program for promising spinal cord and traumatic brain injury research. (Photo by T.W. Budig) A freshman Democrat, she has a background as a caregiver for people with spinal cord injuries. So the proposed creation of the Jablonski/Roderick Spinal Cord and Traumatic Brain Injury Grant Program is emotional. Its an issue very close to my heart, Halverson said. Halverson and Sen. Jeff Hayden, DFL-Minneapolis, admit their legislation faces challenges. They have no funding source for the $4 million a year they want the grant program funded. Read the original: Bill would fund research for spine, brain injuries … Continue reading

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Oxygen chamber can boost brain repair

Posted: Published on January 24th, 2013

Public release date: 23-Jan-2013 [ | E-mail | Share ] Contact: George Hunka ghunka@aftau.org 212-742-9070 American Friends of Tel Aviv University Stroke, traumatic injury, and metabolic disorder are major causes of brain damage and permanent disabilities, including motor dysfunction, psychological disorders, memory loss, and more. Current therapy and rehab programs aim to help patients heal, but they often have limited success. Now Dr. Shai Efrati of Tel Aviv University's Sackler Faculty of Medicine has found a way to restore a significant amount of neurological function in brain tissue thought to be chronically damaged even years after initial injury. Theorizing that high levels of oxygen could reinvigorate dormant neurons, Dr. Efrati and his fellow researchers, including Prof. Eshel Ben-Jacob of TAU's School of Physics and Astronomy and the Segol School of Neuroscience, recruited post-stroke patients for hyperbaric oxygen therapy (HBOT) sessions in high pressure chambers that contain oxygen-rich air which increases oxygen levels in the body tenfold. Analysis of brain imaging showed significantly increased neuronal activity after a two-month period of HBOT treatment compared to control periods of non-treatment, reported Dr. Efrati in PLoS ONE. Patients experienced improvements such as a reversal of paralysis, increased sensation, and renewed use of language. … Continue reading

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Experts in the Field of Traumatic Brain Injury Research to Meet at March Conference in Washington D.C.

Posted: Published on January 24th, 2013

MINNEAPOLIS--(BUSINESS WIRE)-- The worlds leading scientific experts in the field of traumatic brain injury will meet on March 6-7, 2013 in Washington, DC for the 3rd Annual Traumatic Brain Injury Conference, hosted by Arrowhead Publishers. Traumatic Brain Injury (TBI) is a major cause of death and disability in the United States and around the world. In the US alone, an estimated 1.7 million people sustain a traumatic brain injury every year and over 30 percent of all reported injury-related deaths list TBI as a contributing factor. The intent of this conference is to provide attendees with a holistic perspective on the diagnosis, treatment and outcomes associated with traumatic brain injury. In order to better understand how best to achieve the goal of bringing new therapies to market for TBI, speakers will be presenting novel research in the following areas: The need for consensus on these key subject areas will drive lively and enlightening discussions. The two day conference will feature a wide range of TBI experts from academia, industry, military and government. Some of the featured speakers include: More than thirty experts in the field will be participating in plenary and panel sessions at this dynamic event. Please visit http://www.tbiconference.comContinue reading

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