Scientists have successfully transplanted stem cells from donors into patients who suffered heart attacks and reduced their heart damage. The new research suggests stem cells donated by strangers proved as safe and effective as patients' own cells for helping restore heart tissue. The study, published in the Nov. 5 issue of the Journal of the American Medical Association, involved only 30 patients in Miami and Baltimore, but it proves the concept that anyone's cells can be used to treat such cases. Doctors are excited because this suggests that stem cells could be banked for off-the-shelf use after heart attacks, just as blood is kept on hand now. Results were also discussed Monday at an American Heart Association conference in Los Angeles. The study used a specific type of stem cells from bone marrow, called mesenchymal stem cells, that researchers believed would not be rejected by recipients' immune systems. Unlike other cells, these lack a key feature on their surface that makes the body's protective antibodies see them as foreign tissue and attack them, explained the study's leader, Dr. Joshua Hare, director of the Interdisciplinary Stem Cell Institute at the University of Miami. Study participants had suffered heart attacks years earlier, … Continue reading
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