CAMBRIDGE, Mass., Oct. 10, 2012 /PRNewswire/ -- DART Therapeutics, LLC, an innovative, new-model biotechnology firm focused on developing therapies for Duchenne Muscular Dystrophy (DMD), announced today the successful completion of a study to evaluate a promising new biomarker for DMD. The biomarker, electrical impedance myography (EIM), is a non-invasive and simple-to-use technique that allows the operator to measure the health of a muscle and track its changes over time. The information can help researchers evaluate how well a treatment is working to halt disease progression, which could support more precise drug therapy for DMD boys and faster, less expensive drug development for the disease overall. DMD is a progressive and fatal neuromuscular disease for which there is no effective treatment. Current drug development efforts rely on patient outcomes measurements that are either invasive and poorly tolerated or highly subjective and prone to variability. This can have a negative impact on the value of the studies, which must generate results that can be measured and reproduced over time. EIM is based on the observation that as a muscle becomes progressively diseased, an applied weak electrical current moves through it differently. The technique could provide drug developers with a highly precise way … Continue reading
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