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Screening for post-stroke depression inadequate and inconsistent, study finds

Posted: Published on October 1st, 2012

ScienceDaily (Oct. 1, 2012) Physicians are prescribing anti-depressants for stroke patients without first giving them a proper diagnosis, they are over-treating some patients, and overlooking others, according to a study presented October 1 at the Canadian Stroke Congress. "A lot of people are being treated for depression, but we don't know if they're the right ones," says lead researcher Ms. Katherine Salter of Parkwood Hospital in London, Ontario. "This study found that 40 per cent of stroke patients were treated for depression, but most were not screened or diagnosed. Who are we treating?" Researchers examined medical charts for 294 patients discharged from five in-patient rehabilitation programs in southwestern Ontario over a six-month period beginning in September 2010. Only three of 294 patients given an antidepressant were formally screened, assessed and diagnosed with depression first. However, 40 per cent of all patients, whether or not they were screened or assessed for the condition, received treatment for depression. Depression is the most common mental health issue following stroke, affecting more than a quarter of all stroke patients. Depression may affect a patient's ability to participate in post-stroke therapy and is associated with slower progress in rehabilitation and longer stay in hospital. Researchers … Continue reading

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Rehabilitation robots uncover stroke disabilities and improve care

Posted: Published on October 1st, 2012

ScienceDaily (Oct. 1, 2012) When it comes to stroke rehabilitation, it takes a dedicated team to help a person regain as much independence as possible: physicians, nurses, physiotherapists, occupational therapists, speech-language pathologists, recreation therapists, caregivers and others. Now, a University of Calgary research team has added a robot to help identify and customize post-stroke therapy. Rehabilitation robots improve detection of post-stroke impairments and can enhance the type and intensity of therapy required for recovery, according to a study presented October 1 at the Canadian Stroke Congress. Researchers studied 185 subjects -- 87 recovering from stroke and 98 people unaffected by stroke -- and found that tests using a robot better measure patients' sense of limb position, speed and direction of limb movement. Patients were assessed approximately 15 days after stroke. "For years, therapists have known that limb awareness is very important to predicting a person's outcomes after stroke. Yet we have never before been able to quantify it," says lead researcher Dr. Sean Dukelow. "Identifying these deficits opens the door to the next step: how do we treat it?" Until now, rehabilitation experts have relied on their judgment and subjective rating scales to assess impairment after stroke. Robotic technology standardizes … Continue reading

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Home-based stroke therapy improves outcomes, eliminates wait times, saves money

Posted: Published on October 1st, 2012

Public release date: 1-Oct-2012 [ | E-mail | Share ] Contact: Cathy Campbell cathy@canadianstrokenetwork.ca 613-852-2303 Heart and Stroke Foundation of Canada Home delivery of stroke rehabilitation improves care, eliminates waiting lists for treatment and saves hundreds of thousands of dollars annually in hospital costs, according to a quality improvement project presented today at the Canadian Stroke Congress. Early Supported Discharge, introduced as a permanent part of the Calgary Stroke Program in 2011, has resulted in equally good or better cognition, communication and physical function for people who receive therapy in their own homes as opposed to in a hospital or facility. Not only that, the program has helped to virtually eliminate waiting lists for inpatient stroke therapy in Calgary, reduced lengths of stay in inpatient rehabilitation by an average 12 days, and saved approximately $1 million in the first year. The 160 Calgary residents who received therapy in their homes for an average of five weeks following stroke saw significant improvements in knowledge use, upper limb use, domestic life and interpersonal interactions. All participants said they would recommend this approach to other people with stroke. The program "blurs the boundaries between different disciplines providing care," including occupational therapy, physical therapy, … Continue reading

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Home-based stroke therapy improves outcomes, eliminates wait times, saves money, study suggests

Posted: Published on October 1st, 2012

ScienceDaily (Oct. 1, 2012) Home delivery of stroke rehabilitation improves care, eliminates waiting lists for treatment and saves hundreds of thousands of dollars annually in hospital costs, according to a quality improvement project presented October 1 at the Canadian Stroke Congress. Early Supported Discharge, introduced as a permanent part of the Calgary Stroke Program in 2011, has resulted in equally good or better cognition, communication and physical function for people who receive therapy in their own homes as opposed to in a hospital or facility. Not only that, the program has helped to virtually eliminate waiting lists for inpatient stroke therapy in Calgary, reduced lengths of stay in inpatient rehabilitation by an average 12 days, and saved approximately $1 million in the first year. The 160 Calgary residents who received therapy in their homes for an average of five weeks following stroke saw significant improvements in knowledge use, upper limb use, domestic life and interpersonal interactions. All participants said they would recommend this approach to other people with stroke. The program "blurs the boundaries between different disciplines providing care," including occupational therapy, physical therapy, recreation therapy, speech-language pathology, social work and nursing, says project lead Darren Knox, Unit Manager of … Continue reading

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Amarantus BioSciences Announces Landmark MANF Genomics Publication

Posted: Published on October 1st, 2012

SUNNYVALE, Calif., Oct. 1, 2012 /PRNewswire/ -- Amarantus BioSciences, Inc. (AMBS), a biotechnology company developing new treatments for brain-related disorders including Parkinson's disease and Traumatic Brain Injuries (TBI) centered on its proprietary anti-apoptotic therapeutic protein known as MANF, today announced the publication of a landmark research paper on MANF, Amarantus' lead development program. The studies were conducted at the University of Helsinki, a research institution based in Helsinki, Finland, performing groundbreaking neuroscience research based in its' Department of Biosciences and Institute of Biotechnology. This research paper, published by Palgi et al., from Dr. Tapio Heino's laboratory at the University of Helsinki in the peer-reviewed journal BMC Genomics is entitled "Gene expression analysis of Drosophila Manf mutants reveals perturbations in membrane traffic and major metabolic changes," in which researchers describe the critical role MANF plays in the endoplasmic reticulum, the unfolded protein response (UPR), and dopaminergic neurons which are affected by Parkinson's Disease. http://www.ncbi.nlm.nih.gov/pubmed/22494833. "This publication marks a significant advancement in our understanding of how the MANF molecule works in improving overall cellular function," said Dr. John W. Commissiong, Founder & Chief Scientist at Amarantus. "This could be very significant as the MANF Program is advanced for Parkinson's disease" The MANF-family … Continue reading

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On the treatment of children with CEREBRAL PALSY of Altai Krai will provide 59 million rubles

Posted: Published on October 1st, 2012

Programme for the rehabilitation and treatment of children with cerebral palsy has approved Governor of Altai Krai Alexander Karlin. As reported BakuToday in the main Office for the health care and pharmaceutical activity in the region, over three years at its financing of the planned 59 million rubles. Including the provincial budget-56.4 million rubles. 2.6 million rubles are planned to attract extrabudgetary resources. The programme is planned to create in the Altai territory register of children with cerebral palsy and disabled children with consequences of CEREBRAL PALSY. Purchase medical equipment (fizioapparatura, sensory and playrooms, gyms, offices of Montessori teaching materials, surgical equipment) for regional medical institutions engaged in medical treatment and rehabilitation to children with CEREBRAL PALSY. Planned specials kinezioterapevtov doctors, pedagogues, defectologists, psychologists, masseurs, instructors LFK. Through the implementation of the programme is scheduled for 2015, to increase early diagnosis of CEREBRAL PALSY in children of up to 95%; increase the number of medical institutions working in the field of treatment and rehabilitation of children with cerebral palsy. It is also planned to increase the number of rehabilitation of children with cerebral palsy, reduce disability among children with this disease. Note: the total number of children and adolescents with … Continue reading

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Suicide among veterans receiving less attention than active-duty deaths

Posted: Published on October 1st, 2012

After coming home from Iraq, Ray Rivas life had become a grind of rehab and chronic pain from a brain injury. On that morning in July 2009, he told his wife he hadnt slept the night before the headaches that had plagued him since a mortar shell exploded near him three years earlier often robbed him of sleep. But Colleen Rivas said her husband was in good spirits as he drove away from their New Braunfels home. He left with a doughnut in his hand and a smile on his face, she said. Instead of going to his vocational rehab session at Easter Seals in San Antonio, the 53-year-old Army Reserve lieutenant colonel drove to Brooke Army Medical Center and overdosed on sleeping pills in a parking lot. A suicide note was found with his body. I was totally caught off guard, Colleen Rivas said. Three years later, Im still shocked at what he did. A drumbeat of media attention has accompanied the toll of active-duty suicides, along with a stack of official reports with titles like Losing the Battle: The Challenge of Military Suicide and growing alarm from the Department of Defense and Congress. Military suicides jumped about 50 … Continue reading

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Flu Drug Helps Brain Injuries?

Posted: Published on October 1st, 2012

BACKGROUND: Traumatic brain injuries are a form of acquired brain injury in which a sudden trauma causes damage to the brain. This can occur when an individuals head suddenly and violently hits an object, such as can happen in car accidents, or if something pierces the scull and damages the brain tissue. Not all brain injuries are caused by trauma to a persons head and some are the result of brain bleeds, known as hemorrhages. Around half of patients with a severe brain injury will need surgery to repair ruptured blood vessels known as hematomas, or bruised brain tissue called contusions. However, the severity of the brain injury can vary significantly, depending on how much damage to the brain occurred. SYMPTOMS: There are some symptoms associated with traumatic brain injuries ranging from mild, moderate, to severe: Mild traumatic brain injuriesmay cause headaches, blurred vision, ringing in the ears, a bad taste in the mouth, behavioral or mood changes, and trouble with memory, attention, concentration, and thinking. People with a mild traumatic brain injury also normally do not lose consciousness at the time of the injury, or if they do, only for a few minutes. Moderate to severe traumatic brain injuries … Continue reading

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Medistem and Superview Biotechnology Co. Ltd. Initiate Collaboration on Therapeutics Development Using Antibody and …

Posted: Published on October 1st, 2012

SAN DIEGO--(BUSINESS WIRE)-- Medistem Inc (Pink Sheets:MEDS) announced today the initiation of a collaboration with Superview Biotechnology Co. Ltd, a subsidiary of Yinhuan Holding Co from Yixing, China. The joint work will be aimed at using proprietary stem cell lines developed by Medistem for screening of monoclonal antibodies for therapeutic activity in the area of regenerative medicine. As part of the collaboration, the two companies will evaluate various candidates jointly, as well as apply for grants and share research data. To date, the majority of stem cell companies are focusing on the stem cell itself being a product. By collaborating with Superview Biotechnology, we aim to assess the feasibility of developing antibodies that can modulate the activity of stem cells that already exist in the body, said Thomas Ichim, CEO of Medistem. This approach not only provides methods of activating stem cells but also allows for the development of stem cell adjuvant therapies that could be used to resurrect stem cell candidates that failed in clinical trials. Superview Biotechnology has developed proprietary methods of rapidly generating monoclonal antibodies to esoteric protein targets. Medistem has a history of success in the area of stem cells, being the only company to take … Continue reading

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Personalized Medicine's Transformation of Healthcare Accelerates

Posted: Published on October 1st, 2012

SAN FRANCISCO, CA--(Marketwire - Oct 1, 2012) - The life sciences sector continued to outperform the broader markets in September, but developments during the month were notable for highlighting the acceleration of the transformation of healthcare through personalized medicine, Burrill & Company says. "Our healthcare system is dysfunctional and has largely been unchanged through human history in its episodic approach that focuses on treating the symptoms of illness," says G. Steven Burrill, CEO of Burrill & Company, a diversified global financial services firm. "Although personalized medicine's transformation of healthcare is an evolutionary rather than a revolutionary process, the events of the past month point to a rapid acceleration of efforts to make medicine personalized, predictive, and pre-emptive and promises to bend the cost-curve of healthcare in a meaningful way." The University of Texas MD Anderson Cancer Center's announced an ambitious $3 billion Cancer Moon Shots Program, which seeks to develop new diagnostics, devices, drugs, and policies to detect, prevent, and treat cancer by capitalizing on the convergence of low-cost sequencing, artificial intelligence, and other emerging technologies. September also saw a number of developments on the sequencing front. Chinese sequencing giant BGI-Shenzhen announced a $117.6 million acquisition of the struggling next-generation … Continue reading

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