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Disability caused by traumatic brain injury in children may persist and stop improving after two years

Posted: Published on September 19th, 2012

ScienceDaily (Sep. 18, 2012) A child who suffers a moderate or severe traumatic brain injury (TBI) may still have substantial functional disabilities and reduced quality of life 2 years after the injury. After those first 2 years, further improvement may be minimal. Better interventions are needed to prevent long-lasting consequences of TBI in children conclude the authors of a study published in Journal of Neurotrauma, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. Frederick Rivara and colleagues from University of Washington, Seattle, and Mary Bridge Children's Hospital, Tacoma, WA, and Children's Hospital of Philadelphia and the University of Pennsylvania, Philadelphia, PA, describe the functional and quality of life outcomes of children who experienced a moderate or severe TBI when they were 0-17 years of age. In the article "Persistence of Disability 24 to 36 Months after Pediatric Traumatic Brain Injury: A Cohort Study" they follow up on a previous report that found improvement in some areas of functioning for up to 24 months. In this expanded study, the authors showed no significant improvement in the children's ability to function, participate in activities, or in their quality of life between 24 and 36 months post-injury, and they suggest that a … Continue reading

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Don't sack me, sack them

Posted: Published on September 19th, 2012

Video will begin in 5 seconds. Sacked MLC principal Rosa Storelli tells 3AW despite raising issues of her own overpayment in January, she was never shown the 'fictitious' report that led to the decision to remove her from her post. Sacked Methodist Ladies College principal Rosa Storelli has launched a stinging attack on the board of the elite Melbourne girl's school, accusing its chair of "gross mismanagement" and calling for its members to be fired in the wake of her treatment. Ms Storelli, one of the country's most high-profile school leaders, claims she first alerted the board about her overpayments in January this year and now feels violated by her sudden sacking, which was akin to bullying. Sacked Methodist Ladies College principal Rosa Storelli denies any wrongdoing. Photo: Angela Wylie The Age understands that MLC's board of directors believes Ms Storelli was overpaid by more than half a million dollars over her 15 years as principal. Advertisement The nine non-executive directors of the prestigious Kew school unanimously voted to terminate Ms Storelli's employment after the board said a Deloitte review revealed, among other matters, "significant overpayments of remuneration to Ms Storelli". But Ms Storelli says she has never been shown … Continue reading

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Sacked MLC principal slams 'bully' board

Posted: Published on September 19th, 2012

Video will begin in 5 seconds. Sacked MLC principal Rosa Storelli tells 3AW despite raising issues of her own overpayment in January, she was never shown the 'fictitious' report that led to the decision to remove her from her post. Sacked Methodist Ladies College principal Rosa Storelli has launched a stinging attack on the board of the elite Melbourne girl's school, accusing its chair of "gross mismanagement" and calling for its members to be fired in the wake of her treatment. Ms Storelli, one of the country's most high-profile school leaders, claims she first alerted the board about her overpayments in January this year and now feels violated by her sudden sacking, which was akin to bullying. Sacked Methodist Ladies College principal Rosa Storelli denies any wrongdoing. Photo: Angela Wylie The Age understands that MLC's board of directors believes Ms Storelli was overpaid by more than half a million dollars over her 15 years as principal. Advertisement The nine non-executive directors of the prestigious Kew school unanimously voted to terminate Ms Storelli's employment after the board said a Deloitte review revealed, among other matters, "significant overpayments of remuneration to Ms Storelli". But Ms Storelli says she has never been shown … Continue reading

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Earl Campbell, son raise awareness for MS

Posted: Published on September 19th, 2012

To view our videos, you need to enable JavaScript. Learn how. install Adobe Flash 9 or above. Install now. Then come back here and refresh the page. This week, the former Longhorn and NFL star is beginning treatment for a progressive nerve condition. The treatment comes as he continues to help his son, Tyler, in his fight with multiple sclerosis. Tyler Campbell comes from a family of fighters. His father, football legend Earl Campbell, began working with two of the University of Texas strength coaches in March to make it to mid field for the coin toss during the Longhorn's football game against New Mexico Sept. 8. He was able to accomplish that goal thanks to those coaches. When I go to the university, I never mess with that walker. They make me do it all on the crutch, Football Legend Earl Campbell said. All I had to do was show up so my part was pretty easy. Life hasn't been easy for the hall of famer. His body took a beating during his NFL career as a running back with the Houston Oilers and later the New Orleans Saints, suffering severe back and knee pain. I did something to … Continue reading

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ViroPharma To Host Analyst And Investor Seminar On September 21, 2012

Posted: Published on September 19th, 2012

EXTON, Pa., Sept. 18, 2012 /PRNewswire/ -- ViroPharma Incorporated (VPHM) announced today that the company will provide a live audio and slide webcast of its analyst and investor seminar, focusing on the company's commercial product projections and future growth opportunities on Friday, September 21, 2012. Lectures will be provided by a number of ViroPharma representatives. The seminar, entitled "Broadening Horizons," will be held from 9:00 A.M. until 12:45 P.M. Eastern Time on Friday, September 21, 2012. Among the topics ViroPharma will discuss are: plans and opportunities for furthering Cinryze (C1 esterase inhibitor [human]) growth in North America; updates on launch progress and projections for Cinryze, Buccolam (midazolam, oromucosal solution), and Plenadren (hydrocortisone, modified release tablet) in the European Union; development pipeline updates including interim data from select clinical studies; and a financial overview, including longer term financial guidance. "We are excited to be in position to not only provide continued growth with our cornerstone product, Cinryze, here in North America and in Europe, but also to be moving ahead on numerous other commercial products and development opportunities to deliver sustained growth well into the back half of the decade and beyond," commented Vincent Milano, ViroPharma's president and chief executive officer. … Continue reading

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RBCC Explores NASA Technology in Stem Cell Search

Posted: Published on September 19th, 2012

NOKOMIS, Fla.--(BUSINESS WIRE)-- Rainbow Biosciences, the biotech subsidiary of Rainbow Coral Corp. (RBCC), announced today that it is exploring the possible use of micro-gravity technology developed by NASA to produce three-dimensional adult stem cells for medical research purposes. RBCC announced on Monday that it will expand its focus on technology capable of culturing 3D cell clusters to include adult stem cells. The company is currently investigating the potential for a bioreactor developed for the space program to grow tissues from adult stem cells for possible study and even transplantation. Stem cells grown using the NASA technology multiply rapidly and remain three dimensional, unlike the two-dimensional cells grown in Petri dishes. This characteristic makes possible the production of healthy populations of cheaper and higher-quality stem cells suitable for all manner of research. This technology has the potential to be one of NASAs greatest gifts to medical sciences, said RBCC CEO Patrick Brown. The ability to cultivate adult stem cells in a micro-gravity environment here on earth could prove to be a great leap forward in the field of biotechnology, and were very interested in discussing how we might be able to assist in the development and marketing of new therapies and … Continue reading

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San Francisco Dentist Follows Stem Cell Research Regarding Craniofacial Tissue Renewal

Posted: Published on September 19th, 2012

SAN FRANCISCO, Sept. 18, 2012 /PRNewswire/ -- Case results published in the journal Cell Transplantation revealed that human craniofacial tissues regenerate faster using stem cells than with traditional bone regeneration therapy. San Francisco dentist Dr. Greg Larson awaits the benefits this research has in store for restorative dentistry treatments. The University of Michigan School of Dentistry, the Michigan Center for Oral Health Research and Aastrom Biosciences, Inc. in Ann Arbor, Mich., performed research in a dual effort. Clinical trials included 24 participants needing jawbone reconstruction following tooth extraction. Researchers prescribed some participants bone regeneration therapy, while others received ixmyelocel-T cells, developed by Aastrom Biosciences. Aastrom researchers used the bone marrow of participants to create a variety of cell types, including stem cells that would later be implanted into their mouths and jaws. "Patients who received tissue repair cells achieved greater bone density and quicker bone renewal and required less bone grafting during implant procedures when compared to those who underwent traditional guided bone regeneration therapy," according to the U-M press release. U-M School of Dentistry Assistant Professor Darnell Kaigler says the regenerated bone will provide dentists with a stronger foundation when using dental implants. By replacing missing teeth with dental … Continue reading

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Researchers Link Genetic Mutation To Rare Form Of Diabetes

Posted: Published on September 19th, 2012

Alan McStravick for redOrbit.com Your Universe Online A recent study, conducted by researchers at the Washington University School of Medicine in St. Louis and their partners at the Joslin Diabetes Center in Boston and the Novartis Institutes for Bio Medical Research, has managed to identify a specific genetic mechanism connected to mutations in the WFS1 gene that affects insulin-secreting beta cells. It is believed that this discovery will be paramount in increasing the understanding of the rare genetic disorder Wolfram Syndrome (WS) and may also be an important development in the treatment of milder forms of diabetes and related disorders. The full study has been published online in the journal Nature Cell Biology. Wolfram Syndrome is a rare genetic condition that is caused by mutations in a single gene. This minute mutation, however, has far reaching effects on the body leading to conditions such as diabetes, hearing and vision loss and nerve cell damage that can cause motor difficulties and, ultimately, early death. WS was first observed in 1938 as a combination of familial juvenile-onset diabetes and optic atrophy. It was understood even then that for most of the patients with this progressive disorder, premature death and widespread atrophic changes … Continue reading

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Canadian stem cell trials impeded by federal regulations: doctors

Posted: Published on September 19th, 2012

When a Swiss-based researcher announced this month he had achieved some improvement in profoundly paralyzed spinal-cord-injury patients with an injection of stem cells, he generated headlines worldwide. Dr. Armin Curts findings were the first evidence from actual humans though far from conclusive that the much-hyped stem-cell concept might work in paraplegic and quadriplegic patients. What went unsaid was that the breakthrough could have taken place in Canada. Dr. Curt, then working in Vancouver, and Dr. Michael Fehlings, a Toronto-based leader in the field, had earlier proposed that the clinical trial be conducted here. Federal regulators, however, are essentially standing in the way of studying stem-cell treatments on spinal-cord patients, insisting that promising results achieved in rats and mice be first replicated in monkeys or apes, the two researchers say. Such non-human primate studies would be extraordinarily costly, highly time-consuming and ethically challenging, said Dr. Fehlings, medical director of the Krembil Neuroscience Centre at Toronto Western Hospital. And he said little would be gained by conducting them. It probably would have delayed the field by another 10 years, said the neurosurgeon. When you think about a condition as serious and life-threatening and damaging as spinal cord injury is that a reasonable … Continue reading

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Stem cell therapy to lead DOT’s proposed ‘medical tourism’ plan

Posted: Published on September 19th, 2012

The Department of Tourism plans to add another reason for more visitors to come to the country through a soon-to-be drafted medical tourism plan, which highlights the relatively cheap yet world-class health services some of the countrys hospitals have to offer. In this proposed plan, DOT Secretary Ramon Jimenez aims to get the countrys medical sector to put its best foot forward by highlighting stem cell therapy as well as other areas of specialization. Medical tourism focuses on some very serious, important areas of healthcare that the world will travel for, Jimenez said during a forum on stem cell science conducted at the Medical City hospital in Pasig City on Tuesday evening. Through promoting world-class medical services in the country, such as some of Philippine hospitals stem cell programs, Jimenez said the DOT aims to draw foreigners into the country who, in his words, yung sasakay sila ng eroplano, tatawid sila ng dagat. (Foreigners) would obviously spend less if they sought care in their own country like the United States or (places in) Europe. So you really have to have a value that will mitigate the cost of that travel. Your service has to be superior, greater value for their … Continue reading

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