Page 6,520«..1020..6,5196,5206,5216,522..6,5306,540..»

Targeted oxidation-blocker prevents secondary damage after traumatic brain injury, study suggests

Posted: Published on August 27th, 2012

ScienceDaily (Aug. 26, 2012) Treatment with an agent that blocks the oxidation of an important component of the mitochondrial membrane prevented the secondary damage of severe traumatic brain injury and preserved function that would otherwise have been impaired, according to a research team from the University of Pittsburgh School of Medicine, Graduate School of Public Health and Department of Chemistry in a report published online August 26 in Nature Neuroscience. Annually, an estimated 1.7 million Americans sustain a traumatic brain injury (TBI) due to traffic accidents, falls, assaults and sports participation, said the study's senior author Hlya Bayr, M.D., associate professor, Department of Critical Care Medicine, University of Pittsburgh School of Medicine. She added that 52,000 of those injured die, and 85,000 are left with significant disability. "We don't yet have a specific therapy for TBI, but can provide only supportive care to try to ease symptoms," Dr. Bayr said. "Our study drug shows promise as a neuroprotective agent that might help address this important public health problem." For the study, the research team conducted a global assessment of all the phospholipids in rat brain cells. This revealed that damage from TBI was nonrandom and mostly involved cardiolipin, a phospholipid … Continue reading

Posted in Brain Injury Treatment | Comments Off on Targeted oxidation-blocker prevents secondary damage after traumatic brain injury, study suggests

Pitt: Targeted oxidation-blocker prevents secondary damage after traumatic brain injury

Posted: Published on August 27th, 2012

Public release date: 26-Aug-2012 [ | E-mail | Share ] Contact: Anita Srikameswaran SrikamAV@upmc.edu 412-578-9193 University of Pittsburgh Schools of the Health Sciences PITTSBURGH, Aug. 26, 2012 Treatment with an agent that blocks the oxidation of an important component of the mitochondrial membrane prevented the secondary damage of severe traumatic brain injury and preserved function that would otherwise have been impaired, according to a research team from the University of Pittsburgh School of Medicine, Graduate School of Public Health and Department of Chemistry in a report published online today in Nature Neuroscience. Annually, an estimated 1.7 million Americans sustain a traumatic brain injury (TBI) due to traffic accidents, falls, assaults and sports participation, said the study's senior author Hlya Bayr, M.D., associate professor, Department of Critical Care Medicine, University of Pittsburgh School of Medicine. She added that 52,000 of those injured die, and 85,000 are left with significant disability. "We don't yet have a specific therapy for TBI, but can provide only supportive care to try to ease symptoms," Dr. Bayr said. "Our study drug shows promise as a neuroprotective agent that might help address this important public health problem." For the study, the research team conducted a global assessment … Continue reading

Posted in Brain Injury Treatment | Comments Off on Pitt: Targeted oxidation-blocker prevents secondary damage after traumatic brain injury

Nice try Chelsea! Ms Healy tries to go classy but still looks brassy in an all-black outfit

Posted: Published on August 27th, 2012

By Daily Mail Reporter PUBLISHED: 08:45 EST, 26 August 2012 | UPDATED: 10:51 EST, 26 August 2012 'Just wear black' is usually trusted advice - but Chelsee Healy proves she is a walking fashion disaster in any colour. Full credit to the 24-year-old Strictly Come Dancing star for trying in her black off the shoulder top and tight trousers for a shopping trip yesterday (Saturday) as it makes a change to her usual wild clashing coloured look. But Chelsee, who turned up to her own birthday party looking frightful, didn't seem to mind her fashion blunder as she walked the streets in Swinton, Manchester, for the celeb craze treatment, HD Brows. Get ready: Chelsee tries for a classy look but still manages to look a bit brassy out in Manchester The former Waterloo Road star was visiting Natasha Giggs beauty salon, Peace and Pout, in the city. With studded boots and a huge sixties bun Chelsee could have been on her way to a fancy dress party, not a trip to a salon. Chelsee is certainly used to negative comments about her wardrobe. Off the shoulder, off key: Give her credit, Chelsee has gone for a classy look Read more … Continue reading

Posted in MS Treatment | Comments Off on Nice try Chelsea! Ms Healy tries to go classy but still looks brassy in an all-black outfit

U.S. Appeals Court: Government Can Fund Stem Cell Research

Posted: Published on August 27th, 2012

August 26, 2012 April Flowers for redOrbit.com Your Universe Online A three-judge panel at the U.S. Circuit Court of Appeals for the District of Columbia refused to order the Obama administration to stop funding embryonic stem cell research on Friday. This ruling comes despite complaints that the research is dependent on destroyed human embryos. Opponents to the research claim the National Institutes for Health (NIH) is violating the 1996 Dickey-Wicker law which prohibits taxpayer financing for work that harms an embryo. The judges were unanimous, however, in upholding the lower courts decision to throw out the case entirely. This is the second time the appeals court has said that federal funding of stem cell research was permissible. Dickey-Wicker permits federal funding of research projects that utilize already-derived ESCs [Embryonic Stem Cells] which are not themselves embryos because no human embryo or embryos are destroyed in such projects, Chief Judge David B. Sentelle said in the ruling, adding that the plaintiffs made the same argument the last the time the court reviewed the issue. Therefore, unless they have established some extraordinary circumstance, the law of the case is established and we will not revisit the issue. NIH Director Dr. Francis Collins … Continue reading

Posted in Stem Cell Research | Comments Off on U.S. Appeals Court: Government Can Fund Stem Cell Research

UCSF, Mayo Team Discovers Genomic Variant That Increases Risk of Some Brain Tumors

Posted: Published on August 27th, 2012

Newswise People who carry a G instead of an A at a specific spot in the sequence of their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, according to a study by researchers at the University of California, San Francisco and Mayo Clinic. The study was jointly led by geneticists Margaret Wrensch, PhD, and John Wiencke, PhD, professors in the Department of Neurological Surgery at UCSF, and Robert Jenkins, MD, PhD, professor of Laboratory Medicine in the Department of Laboratory Medicine and Pathology and the Division of Laboratory Genetics at the Mayo Clinic. The findings, published on August 26, 2012 in the journal Nature Genetics, could help researchers identify people at risk of developing certain subtypes of gliomas, which account for about 4,600 of the 23,000 brain cancers newly diagnosed annually in the US.This information could lead to better surveillance, diagnosis and treatment. Based on their findings, the scientists already are starting to think about clinical tests that could tell patients with abnormal brain scans what kind of tumor they have, by simply testing their blood. Researchers still need to understand how the specific DNA change actually causes the tumors, said Wrensch, since … Continue reading

Comments Off on UCSF, Mayo Team Discovers Genomic Variant That Increases Risk of Some Brain Tumors

Vitamin B12 deficiency: Tracking the genetic causes

Posted: Published on August 27th, 2012

Public release date: 26-Aug-2012 [ | E-mail | Share ] Contact: Julie Robert julie.robert@muhc.mcgill.ca 514-934-1934 x71381 McGill University Health Centre This release is available in French. Vitamin B12 is essential to human health. However, some people have inherited conditions that leave them unable to process vitamin B12. As a result they are prone to serious health problems, including developmental delay, psychosis, stroke and dementia. An international research team recently discovered a new genetic disease related to vitamin B12 deficiency by identifying a gene that is vital to the transport of vitamin into the cells of the body. This discovery will help doctors better diagnose this rare genetic disorder and open the door to new treatments. The findings are published in the journal Nature Genetics. "We found that a second transport protein was involved in the uptake of the vitamin into the cells, thus providing evidence of another cause of hereditary vitamin B12 deficiency", said Dr. David Rosenblatt, one of the study's co-authors, scientist in medical genetics and genomics at the Research Institute of the McGill University Health Centre (RI MUHC) and Dodd Q. Chu and Family Chair in Medical Genetics and the Chair of the Department of Human Genetics at … Continue reading

Comments Off on Vitamin B12 deficiency: Tracking the genetic causes

Greek Pharmacists to End Prescriptions on Credit

Posted: Published on August 26th, 2012

By Paul Tugwell - 2012-08-26T11:34:57Z The Pan-Hellenic Pharmaceutical Association, which represents Greeces 12,000 pharmacies, said its members will no longer supply drugs prescribed by the countrys National Organization for Health Care Provision without immediate payment in cash starting Sept. 1. Pharmacists called on the organization, Greeces largest state-run health care provider known as Eopyy, to pay outstanding debts of more than 85 days. They also want the government to immediately start financing Eopyy with an amount equal to 0.6 percent of gross domestic product as well as to guarantee bank loans taken by pharmacists, the association said late yesterday in a statement on its website. Eopyy has only made part payment to pharmacists for providing medicines in May and hasnt paid for any prescription drugs since June, the association said Aug. 8. Eopyy still owes money from 2011 at a time when international drug companies no longer offer credit to Greek pharmacists, the association said at the time. It didnt give a figure for the total debt. To contact the reporter on this story: Paul Tugwell in Athens at ptugwell1@bloomberg.net To contact the editor responsible for this story: Jerrold Colten at jcolten@bloomberg.net Read the original post: Greek Pharmacists to End … Continue reading

Posted in Prescriptions | Comments Off on Greek Pharmacists to End Prescriptions on Credit

Handicapped children forced to try dangerous drug, says doctor

Posted: Published on August 26th, 2012

''He used to wake up and have so much energy, then crash and fall asleep by 9am'' ... Harrison White with his mother, Tracy. Mrs White says Harrison's condition improved almost immediately he took modafinil. Photo: Sahlan Hayes CHILDREN with a severe brain disorder are being denied subsidies for a highly effective medication because the government insists they first try a riskier drug, say specialists who refuse to prescribe what they say is an outdated treatment. Chris Seton,a paediatrician at the Children's Hospital at Westmead, said children with narcolepsy - a condition that causes them to fall asleep without warning, gives sudden bouts of muscle weakness and makes concentration difficult - could suffer life-threatening side effects, including psychosis, high blood pressure and heart palpitations, if they took the drug, dexamphetamine. The stimulant is the only therapy routinely subsidised for the condition through the Pharmaceutical Benefits Scheme. ''I will not risk a child suffering the potential side effects,'' Dr Seton said. ''Faced with a choice between the two drugs to treat narcolepsy, nobody on the planet would chose the amphetamine.'' Advertisement Dr Seton said he once admitted a 13-year-old girl to hospital suffering psychosis after she took dexamphetamine before the new … Continue reading

Posted in Drug Side Effects | Comments Off on Handicapped children forced to try dangerous drug, says doctor

We’ll explain the side effects later

Posted: Published on August 26th, 2012

Say you have high blood pressure. Theres a new blockbuster drug on the market, and your doctor lets you know about a new clinical trial you can join that is testing the new treatment against an old tried-and-true one. Whats not to like? Youre going to be taking, under the care of experts, one of two U.S. Food and Drug Administrationapproved medications. What you might not knoweven after you sign up for the trial and have inked the informed-consent formis that scattered reports are starting to suggest that the new medication might occasionally cause severe side effects. And the real reason the trial is being conducted with these previously released drugs is to test whether the new medication really is a lot riskier to everyone or just to a subset of patients. If you found that out, would you still sign up for the trial? The problem is that many patientsand often even the institutional review boards that approve the trialsare never informed of these lingering questions. This is one of the big ethical holes often left open in post-market trials, says Ruth Faden, director of the Johns Hopkins Berman Institute of Bioethics, who co-authored a new essay on this … Continue reading

Posted in Drug Side Effects | Comments Off on We’ll explain the side effects later

Tests show crash drivers took drugs

Posted: Published on August 26th, 2012

More than half the drivers taken to hospital after causing a crash were found to have drugs in their system, a study has found. The Ministry of Transport study used blood samples taken from 453 drivers who caused crashes. Drugs were detected in the systems of 258 drivers, analysis by the Institute of Environmental Science and Research (ESR) found. Of that group, 156 were found to be on drugs not administered by a medical professional Ninety people sent to hospital had both cannabis and alcohol in their system. Yesterday, the Automobile Association renewed its calls for random roadside saliva tests to be used to target drug drivers. Such saliva screening devices can detect only three drugs - cannabis, methamphetamine and Ecstasy - and are used in every Australian state. Police can only drug-test people if they believe they are under the influence. A blood test is carried out if the driver fails an impairment test. "We think the majority of drivers driving with illicit drugs are pretty safe from detection, unfortunately," said the AA's Mike Noon. "They may be caught. But the roadside saliva testing really sends a clear message that if you drug and drive, you could be randomly … Continue reading

Posted in Drugs | Comments Off on Tests show crash drivers took drugs

Page 6,520«..1020..6,5196,5206,5216,522..6,5306,540..»