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Drugs, alcohol possible factors in fatal crash

Posted: Published on August 31st, 2012

Drugs or alcohol are suspected as factors in a crash that claimed the life of a Shenandoah man on Aug. 20. Robert G. Ryan, 46, of Shenandoah recently died at Creighton University Medical Center from injuries suffered in a single-vehicle wreck at U.S. Highway 34 and 28th Street. Ryan and Lyle F. Stogdill, 29, of Shenandoah, were westbound on Highway 34 when their vehicle entered the south ditch for unknown reasons, crossed 288th Street and rolled, according to the Iowa State Patrol. The state patrol has now determined that Stogdill was driving the vehicle which was owned by Ryan, not Darnolds Towing, as incorrectly noted in an earlier story about the crash. Ryan, who was not wearing a seatbelt, was ejected from the truck. According to the state patrol drugs and/or alcohol may have been a factor in the crash. Reporter Mike Brownlee can be reached at (712) 325-5732 or by email at mbrownlee@nonpareilonline.com. The rest is here: Drugs, alcohol possible factors in fatal crash … Continue reading

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Supervalu Administers Flu Shots

Posted: Published on August 31st, 2012

Leading grocery chain Supervalu Inc. (SVU) has started offering flu vaccines to its customers at its pharmacy locations. They also have trained pharmacists at the stores who are also responsible for administering the vaccines. Traditional flu vaccines, needle-free FluMist nasal spray, Fluzone Intradermal and the Fluzone HD for patients aged 65 and above will be available at stores of Supervalu Pharmacies. The shots will be administered at regular pharmacy hours on a walk-in or an appointment basis. Supervalu Pharmacies has 800 locations spread across 25 states and operates under 10 retail brands, namely, Acme Sav-on Pharmacy, Albertsons Sav-on Pharmacy, Albertsons Osco Pharmacy, Cub Pharmacy, Farm Fresh Pharmacy, Jewel-Osco Pharmacy, Shaws Osco Pharmacy, Shop n Save Pharmacy, Shop n Save Osco Pharmacy and Shoppers Pharmacy. Supervalu Pharmacies has been offering adult immunizations since 2000. Apart from administering flu vaccines, Supervalu pharmacy locations also provide immunizations for influenza, pneumococcal disease, tetanus/diphtheria/pertussis, hepatitis A, hepatitis B, cervical cancer, shingles and meningococcal meningitis. The retail chain also provides travel vaccine clinics where customers are immunized if they are traveling to other nations. The vaccination program is expected to boost the second quarter fiscal 2013 sales. The vaccination program is expected to gain popularity as … Continue reading

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Pluristem Files for Orphan Drug Status With U.S. FDA for Use of PLX Cells in Treatment of Aplastic Anemia

Posted: Published on August 30th, 2012

HAIFA, Israel, Aug. 30, 2012 (GLOBE NEWSWIRE) -- Pluristem Therapeutics, Inc. (PSTI) (TASE:PLTR), a leading developer of placenta-based cell therapies, today announced that it has filed the necessary documents requesting that the U.S. Food and Drug Administration (FDA) grant orphan drug status to its PLacental eXpanded (PLX) cells for the treatment of aplastic anemia. The filing marks Pluristem's second orphan drug application to the U.S. FDA. The company applied once before, and successfully received in August of 2011, orphan drug status from the FDA for its PLX cell therapy in the treatment of Buerger's disease. Aplastic anemia is a rare but serious disorder caused by destruction of blood-forming stem cells (Hematopoietic Stem Cells or HSCs) in the bone marrow. While normally HSCs develop into three types of blood cells, red blood cells, white blood cells and platelets, in aplastic anemia all blood types are deficient, a condition also known as pancytopenia. The disease is considered an emergency situation where patients are supported either with blood transfusions in anticipation of a bone marrow transplant (BMT) or with drugs that suppress the immune system. Aplastic anemia patients are included in the bone marrow transplant market estimated at $1.3 billion per year in … Continue reading

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PropThink: Geron Strong After Buy Rating but Investors Look for News on Cancelled Stem Cell Program

Posted: Published on August 30th, 2012

After Stifel Nicolaus initiated a Buy rating on Geron Corporation (GERN) Thursday morning, shares are up 10% to $2.68. The $4 target price initially created 13% gains after the open, but shares have declined slightly as traders take profits off the top. The move marks a 2012 high for Geron since it cancelled its stem cell program in November in favor of a focus on oncology drugs. The company develops Imetelstat, a telomerase inhibitor in Phase 2 trials, and GRN1005 which is entering Phase 2 studies for brain metastases. Imetelstat, the company`s lead compound, is in trials evaluating the drug as a maintenance therapy for metastatic breast cancer, advanced non-small cell lung cancer, essential thrombocythemia and multiple myeloma. It completed enrollment for the NSCLC trial in May and hopes to have top-line data before the end of the year as well as top-line data from the metastatic breast cancer trial in 1Q of 2013. Investors are anxious to learn more about how the discontinuation of Geron`s stem cell program will affect the company`s balance sheet, and whether the cell therapies could still hold long-term value. The program was using embryonic cells to treat spinal cord injuries and had begun FDA-approved … Continue reading

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Cardiovascular Risk Evaluation for All Men Should Include Assessment of Sexual Function

Posted: Published on August 30th, 2012

Report on Princeton III Meeting on Cardiometabolic Risks and Sexual Health Newswise (CHICAGO)-- Assessment of sexual function should be incorporated into cardiovascular risk evaluation for all men, regardless of the presence or absence of known cardiovascular disease, according to Dr. Ajay Nehra, lead author of a report by the Princeton Consensus (Expert Panel) Conference, a collaboration of 22 international, multispecialty researchers. Nehra is vice chairperson, professor and director of Mens Health in the Department of Urology at Rush University Medical Center in Chicago. Erectile dysfunction (ED) is a red flag in younger men, less than 55 years of age for future cardiac morbidity or mortality death or disease for cardiovascular disease (CVD). In some patients, the time window between onset of ED and a cardiovascular event may be two to five years. Any man with ED should be considered at a substantially higher increase cardiovascular risk until further testing can be done, said Nehra. Erectile dysfunction often occurs in the presence of silent, non-symptomatic cardiovascular disease; and hence this is an opportunity for cardiovascular risk reduction. The panel recommends that younger men, more than 30 years old who experience ED receive a thorough, non invasive cardiovascular disease evaluation. As the … Continue reading

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Spider venom could cure erectile dysfunction

Posted: Published on August 30th, 2012

Published: 2:55PM Thursday August 30, 2012 Source: Newstalk ZB/ONE News The Phoneutria, commonly known as the Brazilian Wandering Spider, is the world's most venomous spider. - Source: Supplied. Venom from the world's deadliest spider could cure erectile dysfunction within 20 minutes. Scientists have discovered the Brazilian Wandering Spider's venom boosts performance by increasing the release of nitric oxide, a chemical that dilates blood vessels and improves blood flow. Brazilian scientists first became interested in the deadly spider's ability to boost sexual performance when victims of bites reported major improvements in their sex lives. Researchers from Brazil and the United States extracted the toxin, called PnTx2-6, from the deadly venom and injected it into rats which had age-related erectile dysfunction, Britain's Daily Mail reports. The researchers found the toxin boosted erections by triggering the release of nitric oxide, which boosts circulation in the male genitals by helping blood vessel walls relax. In a report on their findings, published in The Journal of Sexual Medicine, the researchers said: "The decrease in erectile function associated with age was partially restored 15 to 20 minutes after injection with PnTx2-6." Drugs such as Viagra and Cialis have revolutionised treatment in the last 10 years but … Continue reading

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First Drug Formulated for Children with Rare Brain Tumor Approved

Posted: Published on August 30th, 2012

The most common side effects observed in patients with SEGA were mouth ulcers and respiratory tract infections. Afinitor Disperz is recommended to treat patients ages 1 year and older with tuberous sclerosis complex (TSC) who are diagnosed with SEGA that cannot be treated with surgery. Prior to approval of this new dosage form, Afinitor was recommended for use only in patients ages 3 years old and older. Afinitor was granted accelerated approval in 2010 to treat SEGA in patients with TSC. Appropriate pediatric dosage forms, such as Afinitor Disperz, help to ensure the safe and effective use of oncology drugs in children, said Richard Pazdur, M.D., director of the Office of Hematology and Oncology Products in FDAs Center for Drug Evaluation and Research. In addition, todays approval demonstrates the value of further studying a drug to better characterize its benefits and how it should be used in pediatric patients. Afinitor Disperz is available in smaller dose increments than the adult dosage form, Afinitor. Afinitor Disperz also dissolves easily in a small volume of water, making it easy to administer to patients who are unable to swallow whole tablets to take their medication. Afinitors manufacturer, Novartis, also provided updated safety and … Continue reading

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Drugs crack-down hailed a success

Posted: Published on August 30th, 2012

30 August 2012 Last updated at 05:52 ET More than 35,000-worth of drugs have been seized in an operation to combat drug-related violence in Southampton. Hampshire Constabulary said it had made more than 70 arrests in the three months since the launch of Operation Fortress, at the end of May. About 74,000 in cash had also been seized, officers said. Police are also working with councils and other agencies to tackle the root causes of illegal drug use. Det Supt Kath Barnes, who is leading the operation, said: "I'm bowled over by the support we have had for Operation Fortress since we launched it - everybody wants to be a part of this because they can really see that it's making a difference. "We have put over half a dozen people in touch with drug treatment services and adult services." Operation Fortress was set up in response to a number of violent incidents in the city, including a shooting and a number of stabbings. Southampton also has the highest proportion of illegal drug users in Hampshire, according to police. "We are going to make Southampton a really difficult place to operate from for dealers," Det Supt Barnes continued. Follow this … Continue reading

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Resistance to Backup Tuberculosis Drugs Increases

Posted: Published on August 30th, 2012

In countries such as South Africa, drugs commonly used to treat tuberculosis are becoming less effective as strains of the diseases develop resistance. Image: Tom Fox/Dallas Morning News/Corbis Showcasing more than fifty of the most provocative, original, and significant online essays from 2011, The Best Science Writing Online 2012 will change the way... Read More From Nature magazine More than 40% of tuberculosis infections that are resistant to front-line treatments are also resistant to some common backup drugs, according to research published this week in The Lancet1. Efforts to control tuberculosis are being hampered by the emergence of multidrug-resistant (MDR) strains of the disease, which resist treatment with two front-line antibiotics, rifampicin and isoniazid. In some parts of the world, as many as 50% of tuberculosis cases are resistant to these drugs2. Alternative treatment options are toxic and expensive, relying on second-line drugs that are not as effective and must be given in lengthy courses. Unfortunately, the majority of MDRtuberculosis cases occur in developing countries that cant afford the several billion dollars that the global Stop TB Partnershipestimates3 will be required to combat the disease. More recently, strains of tuberculosis have emerged that are resistant not only to front-line antibiotics, … Continue reading

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Deaths fall from misuse of drugs

Posted: Published on August 30th, 2012

30 August 2012 Last updated at 02:23 ET The number of deaths from drugs misuse in Wales fell in 2011, according to the Office for National Statistics (ONS). However, the overall trend has shown a sharp rise in the death rate over the past two decades. Last year 137 people died, but that compared with 33 in 1993 and 89 in 2005. The death rate peaked in 2010 with 152 deaths, and the rate still remains higher in Wales compared with every other region in England, said the ONS. However, Ifor Williams, chief executive of the Swansea Drugs Project, was encouraged by last year's fall in deaths and said it showed education and prevention projects were working. "I think it's important that we take the positive rather than seeing the figures from the last 20 years," he said. There's no real evidence to show there are fewer people taking drugs, but this does show us that education and prevention is taking effect Mr Williams said the Welsh government has been "focused" in the last couple of years on preventing deaths and users have been able to carry the antidote naloxone. Naloxone works by temporarily blocking the effect of the opiate … Continue reading

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