Public release date: 10-Sep-2012 [ | E-mail | Share ] Contact: Dian Land dj.land@hosp.wisc.edu 608-261-1034 University of Wisconsin-Madison MADISON The protein GATA2 is known as a "master regulator" of blood cell development. When a mutation occurs in the gene that makes GATA2, serious blood diseases such as acute myeloid leukemia can result. Zooming in on the GATA2 gene, UW-Madison researchers and their collaborators at the National Institutes of Health (NIH) have discovered unexpectedly that a small DNA sequence drives this powerful master regulator. The sequence plays an essential role in controlling GATA2 production and generating self-renewing blood stem cells responsible for the earliest steps in the development of blood cells of all kindsred cells to transport oxygen and white cells to fight infection. The researchers also found that the DNA sequence, which they call the +9.5 GATA2 switch site, ensures that blood vessels function properly to prevent hemorrhaging. Until now, GATA2 had not been implicated in blood vessel integrity. The study appears in The Journal of Clinical Investigation (online Sept. 10, 2012). Although the study was performed in mice, it should have significant clinical relevance, particularly to physicians and scientists aiming to understand certain types of leukemia and related disorders … Continue reading →

GREEN BAY - Statistics show Americans spend almost $51 billion on their pets every year. A new stem cell treatment for dogs is providing relief for pets and their owners, and now it's being done here in the Green Bay area. It's designed to treat problems like hip dysplasia and arthritis. The procedure can cost thousands of dollars, but pet owners believe it is money well-spent. "Come on buddy," said Keith Moskowiak, De Niro's owner. Ten-year-old German Shepherd De Niro is at the veterinarian's office for a routine check up. Owner Keith Moskowiak says De Niro couldn't have done it just two months ago. "He wasn't able to get around, you could tell he was in a lot of pain," said Moskowiak. Five-year-old Shadow has hip dysplasia. "She was slowing herself down, she truly was. She was reserving herself. She'd run a little bit, then she'd sit," said Luther Kortbein, Shadow's owner. See the rest here: New stem cell treatment for dogs … Continue reading →

Green Bay - You hear about people getting stem cell therapy for various ailments. Now it's even available for your pet. A Northeast Wisconsin veterinary center is the first in the state to offer it. It's not cheap, but we found pet owners feel the results outweigh the cost. Eleven-year-old DeNiro is about to do something he couldn't do when he was ten. Jump. Owner Keith Noskowiak couldn't be happier. "That's awesome seeing him be able to do that again." DeNiro suffered from severe arthritis in his back. A German shepherd named Shadow had hip dysplasia. She could barely walk, let alone jump as she can today, catching balls in flight. "She would whimper all night long because she was starting to hurt. It was starting to get more severe," owner Luther Kortbein says. These two German shepherds were the first dogs to receive stem cell therapy in Wisconsin. Doctor Maura Mansfield from the Packerland Veterinary Center performed the surgeries in June. The rest is here: Stem Cell Therapy Treats Pets … Continue reading →

Green Bay - You hear about people getting stem cell therapy for various ailments. Now it's even available for your pet. A Northeast Wisconsin veterinary center is the first in the state to offer it. It's not cheap, but we found pet owners feel the results outweigh the cost. Eleven-year-old DeNiro is about to do something he couldn't do when he was ten. Jump. Owner Keith Noskowiak couldn't be happier. "That's awesome seeing him be able to do that again." DeNiro suffered from severe arthritis in his back. A German shepherd named Shadow had hip dysplasia. She could barely walk, let alone jump as she can today, catching balls in flight. "She would whimper all night long because she was starting to hurt. It was starting to get more severe," owner Luther Kortbein says. These two German shepherds were the first dogs to receive stem cell therapy in Wisconsin. Doctor Maura Mansfield from the Packerland Veterinary Center performed the surgeries in June. Go here to see the original: Stem Cell Therapy Treats Pets … Continue reading →

GREEN BAY - Statistics show Americans spend almost $51 billion on their pets every year. A new stem cell treatment for dogs is providing relief for pets and their owners, and now it's being done here in the Green Bay area. It's designed to treat problems like hip dysplasia and arthritis. The procedure can cost thousands of dollars, but pet owners believe it is money well-spent. "Come on buddy," said Keith Moskowiak, De Niro's owner. Ten-year-old German Shepherd De Niro is at the veterinarian's office for a routine check up. Owner Keith Moskowiak says De Niro couldn't have done it just two months ago. "He wasn't able to get around, you could tell he was in a lot of pain," said Moskowiak. Five-year-old Shadow has hip dysplasia. "She was slowing herself down, she truly was. She was reserving herself. She'd run a little bit, then she'd sit," said Luther Kortbein, Shadow's owner. See the original post here: New stem cell treatment for dogs … Continue reading →