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Busy Luke still fires stem cell research

Posted: Published on September 4th, 2012

Sept. 4, 2012, 4:07 a.m. Bomaderry toddler Luke Alderton was the face of the political debate over stem cell research. The two-year-old, who could not walk due to a rare spinal condition, featured on the Mercury's front page 10 years ago with NSW Premier Bob Carr sitting on his front lawn. The pair met at Shoalhaven Hospital and the youngster's plight inspired Mr Carr as he lobbied the federal government to embrace medicine's next frontier - the use of human cells, including some from embryos, to regrow damaged tissue. Luke's case was presented to urge politicians to pass laws allowing research on excess IVF embryonic stem cells. It worked. Legislation put forward by then prime minister John Howard, in line with an agreement with the states and territories, to enact uniform stem cell laws got the green light. Today there is still no cure for Luke's condition but he is making the most of the cards he has been dealt. The Mercury caught up with his dad Steve last week to check on Luke's progress. "While his future will always involve hospitals and medical support, overall its very bright," Steve Alderton said from New Zealand, the family's home since 1994. … Continue reading

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Newly identified stem cell population in skin's epidermis responsible for tissue repair

Posted: Published on September 4th, 2012

ScienceDaily (Sep. 3, 2012) Researchers at the Universit Libre de Bruxelles, ULB identify a new stem cell population in the skin epidermis responsible for tissue repair. The skin, which is an essential barrier that protects our body against the external environment, undergoes constant turnover throughout life to replace dead cells that are constantly sloughed off from the skin surface. During adult life, the number of cells produced must exactly compensate the number of cells lost. Different theories have been proposed to explain how this delicate balance is achieved. In a new study published in Nature, researchers lead by Pr. Cdric Blanpain, MD/PhD, FNRS/FRS researcher and WELBIO investigator at the IRIBHM, Universit libre de Bruxelles, Belgium, in collaboration with Pr. Benjamin Simons, University of Cambridge, UK, demonstrate the existence of a new population of stem cells that give rise to progenitor cells that ensure the daily maintenance of the epidermis and demonstrate the major contribution of epidermal stem cells during wound healing. In this new study, Guilhem Mascr and colleagues used novel genetic lineage tracing experiments to fluorescently mark two distinct epidermal cell populations, and follow their survival and contribution to the maintenance of the epidermis overtime. Interestingly, in doing so, … Continue reading

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Paralyzed patients regain some sensory function after neural stem cell treatment

Posted: Published on September 4th, 2012

StemCells' human neural stem cell But, promising new research from a phase 1 study conducted at the University of Zurich sponsored by StemCells, Inc. shows that six months after the implantation of neural stem cells, two out of three complete injury patients - meaning they had no neurological function below the point of injury - were able to gain some sensory function. "We haven't made progress in how to address injury after they occur, but using neural stem cells in a transplant lets us, for the first time, think we can repair this," Dr. Stephen Huhn, a neurosurgeon and the vice president and head of the CNS program at StemCells, Inc. said to HealthPop. The phase 1 study was intended to see if the implantation treatment had any unwanted side effects. For the procedure, 20 million neural stem cells were implanted directly into the spinal cord, something that has never been done before. Then, any reactions were monitored including complex examinations of sensory function - for example light touch, sensitivity to temperature and sensitivity to subtle electronic stimulation - as well as electrostimulation of the spinal cord itself. What researchers were surprised to find was that the neural stem cell … Continue reading

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Scientists restore sense of smell to mice who were born with genetic abnormality

Posted: Published on September 4th, 2012

(CBS News) There may be hope for people who are unable to smell. Using gene therapy, scientists have successfully restored the sense of smell in mice that had a genetic mutation that took away their olfactory senses. Smell disorders or olfactory dysfunction affect one to two percent of people living in North America, according to the National Institute of Deafness and Other Communication Disorders (NIDCD). They partially funded the study along with the National Institute on Diabetes and Digestive and Kidney Diseases (NIDDK), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and the National Eye Institute (NEI). However, smell problems increase with age. A study showed that about 25 percent of men between the ages of 60 to 69 and 11 percent of women in that age group had developed a problem with their sense of smell, NIDCD said. Scientist hypothesize that olfactory dysfunction may be due to a group of genetic disorders called ciliopathies, which include diseases such as polycystic kidney disease and retinitis pigmentosa, an inherited degenerative eye disease that causes severe vision impairment and blindness. Problems with cilia, antenna-like projections on cells that help sense what's around, are the root of these … Continue reading

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Stem cells bring back feeling for paralysed patients

Posted: Published on September 4th, 2012

For the first time, people with broken spines have recovered feeling in previously paralysed areas after receiving injections of neural stem cells. Three people with paralysis received injections of 20 million neural stem cells directly into the injured region of their spinal cord. The cells, acquired from donated fetal brain tissue, were injected between four and eight months after the injuries happened. The patients also received a temporary course of immunosuppressive drugs to limit rejection of the cells. None of the three felt any sensation below their nipples before the treatment. Six months after therapy, two of them had sensations of touch and heat between their chest and belly button. The third patient has not seen any change. "The fact we've seen responses to light touch, heat and electrical impulses so far down in two of the patients is very unexpected," says Stephen Huhn of StemCells, the company in Newark, California, developing and testing the treatment. "They're really close to normal in those areas now in their sensitivity," he adds. "We are very intrigued to see that patients have gained considerable sensory function," says Armin Curt of Balgrist University Hospital in Zurich, Switzerland, where the patients were treated, and principal … Continue reading

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Global Human Embryonic Stem Cell (hESC) Research Industry

Posted: Published on September 4th, 2012

NEW YORK, Sept. 3, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Global Human Embryonic Stem Cell (hESC) Research Industry http://www.reportlinker.com/p0960425/Global-Human-Embryonic-Stem-Cell-hESC-Research-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Biological_Therapy This report analyzes the worldwide markets for Human Embryonic Stem Cell (hESC) Research in US$ Million. The report provides separate comprehensive analytics for the US, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2009 through 2018. The report profiles 26 companies including many key and niche players such as Advanced Cell Technology, Inc., BD Biosciences, BioTime, Inc., Cell Cure Neurosciences Ltd., Cellartis AB, GE Healthcare, Millipore Corporation, Molecular Transfer, Inc., PerkinElmer, Inc., Pfizer, Inc., Research & Diagnostics Systems, Inc., Reliance Life Sciences Ltd., Stem Cell Network, Stemina Biomarker Discovery, Inc., UK Stem Cell Bank, and ViaCyte, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain. I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS Study Reliability and Reporting Limitations I-1 Disclaimers I-2 Data Interpretation & Reporting Level I-2 Quantitative Techniques & Analytics I-3 Product Definitions and Scope of Study I-3 See the rest here: Global Human Embryonic Stem Cell (hESC) Research Industry … Continue reading

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Terahertz Scanners, Drugs, and Shoes

Posted: Published on September 4th, 2012

"A British man sentenced to four years in jail in Dubai after cannabis weighing less than a grain of sugar was found embedded in the tread of his shoe has reportedly been pardoned ... The 43-year-old was arrested in September [2008] at Dubai International Airport ... Customs officers found 0.003 grams (0.0001 ounces) of cannabis in a cigarette stub stuck on the sole of one his shoes." -- Sky News When I read that I wondered how on earth Dubai customs found the traveller's "stash." I mean, just think about it; thousands of people passing through customs every day and the officials can spot something that tiny on the sole of his shoe! There has to be some kind of logical explanation. Before I go any further, I must explain that the United Arab Emirates (the UAE), while considered perhaps the most liberal of the Arab Gulf states, is fanatically (and irrationally) anti-drug to the point where entering the country with melatonin tablets (an over-the-counter medication used to counter jet lag) or traces in your bloodstream of a whole list of chemicals will get you arrested! Want crazier? It was reported in 2008 that a Swiss national went to jail … Continue reading

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Three arrests following Hamp drugs bust

Posted: Published on September 4th, 2012

Three arrests following Hamp drugs bust 4:39pm Monday 3rd September 2012 in News By Newsdesk A DRUGS bust in Bridgwater saw police seize around 2,000 of illegal substances after the public took a stand. Bridgwater police descended on a house in the Hamp area under a Misuse of Drugs Act warrant on Friday (August 31), following information provided by the community. Officers found around 2,000 worth of cannabis plants, dried vegetable matter believed to be cannabis and white powder suspected to be the amphetamine known as Miaow Miaow. The items were sent for forensic testing. A 55-year-old man was arrested at the scene on suspicion of cultivation of cannabis and a 22-year-old man was arrested on suspicion of possession of cannabis and a Class B drug. A 19-year-old woman was also given a cannabis warning for possession. DC David Nash, from Bridgwater Police, said: This was a great result and was due to information provided to us by the public. Residents clearly took a stand against criminal activity in the area and we would encourage the public to keep coming forward with information relating to crime in their community. The cultivation and sale of drugs will not be tolerated in … Continue reading

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Irked by methadone pharmacy

Posted: Published on September 4th, 2012

Residents of an east London neighbourhood are angry they weren't told a pharmacy that recently opened is dispensing methadone. Marsha, a 24-year-old Western University student who didn't want her last name used, organized a protest Monday in a parking lot next door to the newly opened London Drug Mart at 1617 Dundas St. Marsha said she and other neighbours were puzzled why another pharmacy was opening in the area that already has a Shoppers Drug Mart and a Rexall PharmaPlus. When she went in to investigate she found the pharmacy shelves empty. She asked the pharmacist if he distributed methadone and he said yes. Drug users take methadone to help them overcome addictions to morphine and heroin. About 1,400 people in the London area are on methadone. When community members contacted the city about their concerns, they were told the pharmacy didn't need a permit because it serves less than 40 people. Bill Armstrong, the city councillor for the area, said he was informed last week the pharmacy had opened and asked city staff to review the operation and the zoning bylaws. Armstrong said he believes the pharmacy has moved from its previous location at Clarke Rd. and Trafalgar St. … Continue reading

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Oxycodone stolen from Crystal Lake pharmacy

Posted: Published on September 4th, 2012

50 Chicago police officers sent to help at DNC 50 Chicago police officers sent to help at DNC Updated: Monday, September 3 2012 6:51 PM EDT2012-09-03 22:51:23 GMT A spokeswoman for the Chicago Police Department says taxpayer money is not being used to pay for officers on the job in Charlotte this week. A spokeswoman for the Chicago Police Department says taxpayer money is not being used to pay for officers on the job in Charlotte this week. Updated: Monday, September 3 2012 6:45 PM EDT2012-09-03 22:45:37 GMT Parades, picnics and politicians celebrated the American worker on Labor Day. Parades, picnics and politicians celebrated the American worker on Labor Day. Updated: Monday, September 3 2012 6:39 PM EDT2012-09-03 22:39:27 GMT Bears linebacker Brian Urlacher returned to practice Monday for the first time since July 31, hoping to play in Sunday's season opener. Bears linebacker Brian Urlacher returned to practice Monday for the first time since July 31, hoping to play in Sunday's season opener. Original post: Oxycodone stolen from Crystal Lake pharmacy … Continue reading

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