Featured Article Academic Journal Main Category: Bones / Orthopedics Also Included In: Stem Cell Research Article Date: 23 Aug 2012 - 11:00 PDT Current ratings for: Osteoporosis Clue Found In Stem Cell Signalling Protein 1 (1 votes) These are the implications of a new study led by Harvard Medical School (HMS) that was published online in The Journal of Clinical Investigation on 13 August. Senior author Bjorn Olsen, Hersey Professor of Cell Biology at HMS, told the press about what they found: "It shifts the thinking about what controls the differentiation of stem cells to bone cells instead of fat cells, and how to make sure this mechanism stays active with aging." Bone is not a dead material: it is living tissue that is changing all the time, as it is continuously formed and reabsorbed. Osteoporosis is a common bone disease where bone tissue becomes progressively thinner, resulting in higher risk of fracture. It affects about 1 in 5 American women and is thought to be caused by stem cells that normally differentiate into bone-forming cells becoming fat cells instead over time. For the study, Olsen, who is professor of developmental biology and dean for research at Harvard School of … Continue reading
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