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Doctors to study newborn stem cells as treatment for autism

Posted: Published on August 22nd, 2012

SACRAMENTO, CA - At 4-years-old Rydr Rudgers is able to eat, speak, and walk --all thingshis family wasn't sure he'd ever do after being diagnosed with cerebral palsy as an infant. "He was born without any brain stem functions; no sucking, no swallowing, no breathing," said Rydr's mother Elisa. When Rydr was 15-months-old, he began stem cell infusions from his cord blood that was saved in a stem cell bank.Rydris making great progress after three infusionsand can even feed himself. "These are like huge milestones that people don't think about, but actually being able to hold a fork and eat a sandwich is, in our world, an unanticipated milestone and it's amazing," Elisa Rudgers explained. "Like autism, cerebral palsy or brain injuries of that nature are a diffused population, it's not one cause,"said Dr. Michael Chez, who is the Medical Director of Pediatric Neurology at the Sutter Neuroscience Institute. Doctors at the Sutter Neuroscience Institute are now beginning research to evaluate cord blood stem cells to help improve language and behavior in autism patients. The announcement was made on Tuesday morning at Sutter Medical Plaza.It's the first FDA-approved clinical trial that uses a newborn's stem cells from cord blood to … Continue reading

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Stem Cell Study to Enroll 30 Autistic Children

Posted: Published on August 22nd, 2012

Lonnie Wong FOX40 News 1:53 p.m. PDT, August 21, 2012 SACRAMENTO Rydr Rudgers suffers from cerebral palsy. He couldnt move or talk before a cord blood stem cell treatment undertaken during a Duke University study. His doctor, Michael Chez, M.D. is medical director of Pediatric Neurology at Sutter Neuroscience Institute. He is now heading up the first stem cell clinical trial on autism and hopes for similar results. Dr. Chez says autism shares some of the same symptoms as cerebral palsy and that there is plenty of anecdotal evidence that using cord blood stem cells from the patients' own umbilical cord can regenerate brain cells. The study which will employ placebos will determine scientifically whether such treatments make improvements in young autism patients. Sutter Neuroscience Institute got FDA approval for the landmark study and will enroll 30 kids with autism age 2 to 7 to receive injections of their own stem cells. Most parents are given the option of saving their childrens' ubilical cords after birth. Elisa Rudgers is glas she did. Now four years old, Rydr is walking, talking and eating on his own. That wasn't possible without three stem cell therapy injections over several years. After each injection … Continue reading

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To rent pnevmotrenažery children with CEREBRAL PALSY will be in Altai Krai

Posted: Published on August 22nd, 2012

Rent a pnevmotrenaery to treat at home to parents of children with cerebral palsy in Altai Krai. As reported BakuToday in the Altai region on health and pharmaceutical activity, about 8 million. rubles from the edge of the charity Marathon will support the child spent on the acquisition of special equipment for childrens costumes from 1 year to 4 years living with cerebral palsy. Treatment with costumes-pnevmotrenaerov is already in use in medical practice and gives good results. The need for training suits in the province is high, but until the children can use them only in a hospital environment. But thanks to dedicated funds will create Exchange Fund pnevmotrenaerov. Having received the recommendation of a doctor-neurologist, parents kids can take them and use speckostmy at home, which is very convenient, explained before. It is also planned to allocate funds for the purchase of modern medicine-dysport, used in medicine to relieve muscle spasm in patients with cerebral palsy. On the recommendation of his doctors get 106 young inhabitants of the province. After the medical treatment they will appoint a rehabilitation course, which will take place on the basis of the 5-th urban and provincial childrens hospitals, as well as in … Continue reading

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Rewired visual input to sound-processing part of the brain leads to compromised hearing

Posted: Published on August 22nd, 2012

ScienceDaily (Aug. 22, 2012) Scientists at Georgia State University have found that the ability to hear is lessened when, as a result of injury, a region of the brain responsible for processing sounds receives both visual and auditory inputs. Yu-Ting Mao, a former graduate student under Sarah L. Pallas, professor of neuroscience, explored how the brain's ability to change, or neuroplasticity, affected the brain's ability to process sounds when both visual and auditory information is sent to the auditory thalamus. The study was published in the Journal of Neuroscience. The auditory thalamus is the region of the brain responsible for carrying sound information to the auditory cortex, where sound is processed in detail. When a person or animal loses input from one of the senses, such as hearing, the region of the brain that processes that information does not become inactive, but instead gets rewired with input from other sensory systems. In the case of this study, early brain injury resulted in visual inputs into the auditory thalamus, which altered how the auditory cortex processes sounds. The cortical "map" for discriminating different sound frequencies was significantly disrupted, she explained. "One of the possible reasons the sound frequency map is so … Continue reading

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Decision-Making in the Brain Mapped

Posted: Published on August 22nd, 2012

Behavioral control and decision-making take part in different regions of the brain's frontal lobe, new research shows The study effectively created a map of the frontal lobes, making it possible for patients with brain injuries to get an accurate prognosis early in treatment. "That knowledge will be tremendously useful for prognosis after brain injury," Ralph Adolphs, Bren Professor of Psychology and Neuroscience at Caltech and a coauthor of the study published in this week's issue of the Proceedings of the National Academy of Sciences (PNAS), said in a press release. "Many people suffer injury to their frontal lobes -- for instance, after a head injury during an automobile accident -- but the precise pattern of the damage will determine their eventual impairment," he added. BLOG: Could Brain Injuries Unleash Pedophilia? When you're making a decision, several different parts of the brain might be activated. How a person functions after a brain injury depends on precisely where a brain injury occurs. Other parts of the brain might compensate, allowing the person to function typically, or the person might be left with a lifelong hardship in making decisions. "We can use our lesion maps and compare the location of damaged brain areas … Continue reading

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Brain's code for pronouncing vowels uncovered: Discovery may hold key to restoring speech after paralysis

Posted: Published on August 22nd, 2012

ScienceDaily (Aug. 21, 2012) Scientists at UCLA and the Technion, Israel's Institute of Technology, have unraveled how our brain cells encode the pronunciation of individual vowels in speech. Published in the Aug. 21 edition of Nature Communications, the discovery could lead to new technology that verbalizes the unspoken words of people paralyzed by injury or disease. "We know that brain cells fire in a predictable way before we move our bodies," explained Dr. Itzhak Fried, a professor of neurosurgery at the David Geffen School of Medicine at UCLA. "We hypothesized that neurons would also react differently when we pronounce specific sounds. If so, we may one day be able to decode these unique patterns of activity in the brain and translate them into speech." Fried and Technion's Ariel Tankus, formerly a postdoctoral researcher in Fried's lab, followed 11 UCLA epilepsy patients who had electrodes implanted in their brains to pinpoint the origin of their seizures. The researchers recorded neuron activity as the patients uttered one of five vowels or syllables containing the vowels. With Technion's Shy Shoham, the team studied how the neurons encoded vowel articulation at both the single-cell and collective level. The scientists found two areas -- the … Continue reading

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Brain injury survivor uses social media to spread hope

Posted: Published on August 22nd, 2012

For many people, social media is a way to keep in touch with friends and family. For Mike Black, it has become a way to help save lives, starting with his own. On May 21, 2011, Black was involved in a serious car accident in Orlando, Florida. Black was ejected from his vehicle on impact and landed on his head, shearing his brain stem. Black was in a coma for several weeks, and doctors were forced to remove a portion of his brain in an effort to save his life. His prognosis was grim. Black's mother and stepfather, Allen residents Bernadette and Tom Coleman, flew to Orlando to be by his side. Because of the demands Black's care placed on his parents, they often found themselves unable to keep the rest of their family informed of Black's progress. They found a solution through social media, creating a Facebook page called "The Beans Recovery Group." Though the page began as a means to keep family and friends informed of Black's recovery and progress, it soon found a much wider audience. "What's crazy is other people started to join the site," Bernadette Coleman said. "People from all around the world started to … Continue reading

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Sask. man begins MS trial in New York on Wednesday

Posted: Published on August 22nd, 2012

A Saskatoon man with multiple sclerosis will begin his first day of clinical trials for experimental vein therapy Wednesday in Albany, New York. Andrew Dahlen, 28, is the first of 86 MS patients from Saskatchewan selected to participate in the two-year study. The trial will test the so-called "liberation therapy," in which tiny balloons will be surgically inserted to open constricted veins. All of the the participants will undergo the surgery, but only half will receive the treatment. Wednesday afternoon, Dahlen will be given a drug which will cause him to have temporary amnesia only a local anesthetic is needed for the procedure. The drug is given to make sure Dahlen doesn't remember anything that happens in the operating room. His surgeon will then open an envelope revealing whether Dahlen will receive the liberation therapy or not. "It's been stressful, trying not to show it, but it's stressful," Dahlen told CBC News. But Dahlen said he is okay either way. "I feel like I'm doing something good for Saskatchewan, for research," he said. "I also hope I get the procedure, but if I don't, it will be good research," he said. Dahlen won't officially know if he actually received the … Continue reading

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Multiple sclerosis breakthrough raises hope for improved therapies

Posted: Published on August 22nd, 2012

Multiple sclerosis is a prevalent disease that affects about 250,000 to 350,000 Americans, according to the National Institute of Health. This disease afflicts the brain and spinal cord, which make up the central nervous system, and causes the inflammation of the meninges, a lining of cells that cover the surface of the brain. Though this is, as yet, an incurable disease, MS has many treatment and therapeutic options for patients. A group of Wayne State researchers, along with colleagues in Canada, have found a possible pathway that leads to disease progression which could lead to new therapies for patients. WSU School of Medicine neurology associate chair and professor Joyce A. Benjamins, neurology professor Robert P. Lisak, neurology and immunology & microbiology assistant professor Samia Ragheba, neurology research assistants Liljana Nedelkoskaa and Jennifer Barger all contributed to the study. The main idea behind the study was to see if B cells from patients with MS make substances that could be secreted that could damage CNS cells, Lisak said. B cells are a type of lymphocytes, or white blood cells, that produce antibodies, which help the body in immune responses. In patients with multiple sclerosis, however, the B cells produce molecules that … Continue reading

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Global Osteoporosis Therapeutics Industry

Posted: Published on August 22nd, 2012

NEW YORK, Aug. 22, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Global Osteoporosis Therapeutics Industry http://www.reportlinker.com/p080451/Global-Osteoporosis-Therapeutics-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Therapy This report analyzes the worldwide markets for Osteoporosis Therapeutics in US$ Million by the following Therapeutic Classes: Bisphosphonates, ERT Drugs, SERMs, Calcitonins, and MAB (Denosumab). The report provides separate comprehensive analytics for the US, Japan, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2009 through 2017. Also, a six-year historic analysis is provided for these markets. The report profiles 49 companies including many key and niche players such as Abbott Laboratories, Eli Lilly and Company, F.Hoffmann-La Roche Ltd., Merck & Co., Inc., Novartis AG, Novo Nordisk A/S, Pfizer, Inc., Wyeth, Sanofi-Aventis SA, Servier SA, Unigene Laboratories, Inc., and Warner Chilcott plc. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain. I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS Study Reliability and Reporting Limitations I-1 Disclaimers I-2 Data Interpretation & Reporting Level I-3 Quantitative Techniques & Analytics I-3 Product Definitions and Scope of Study I-3 Bisphosphonates I-4 Hormone Replacement Therapy/Estrogen Replacement Therapy I-4 Estrogens I-4 Estrogens/Progesterones I-4 … Continue reading

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