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Cystinosis Research Foundation Awards $1.6 Million in Grants to 11 Research Projects

Posted: Published on August 22nd, 2012

IRVINE, CA--(Marketwire -08/22/12)- Grants totaling more than $1.6 million were awarded by the Cystinosis Research Foundation for 11 new research projects seeking to cure cystinosis and advance new treatments for the rare metabolic and fatal disease. The newly funded studies include research focused on corneal cystinosis, muscle wasting and stem cells. Cystinosis afflicts about 500 children and young adults in the United States and about 2,000 worldwide. The new CRF research will be under way at universities and hospitals in the United States, France, Belgium, Switzerland and New Zealand. Since 2003, the CRF has raised more than $19 million and funded 105 multi-year research studies and fellowships in 11 countries. The CRF is the largest fund provider of cystinosis research. CRF-funded research led to discovery of a dramatic improvement in the life-saving medication and to the first allogeneic stem cell clinical pilot study for cystinosis which is being conducted at the Ronald Reagan UCLA Medical Center. Recently, two CRF-funded researchers were awarded NIH grants totaling more than $3 million, leveraging CRF grant money. "CRF is guided by a Scientific Review Board, a world renowned group of cystinosis experts and scientists who evaluate every research application we receive. Their expertise and … Continue reading

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Earnings Scorecard: Target

Posted: Published on August 22nd, 2012

Target Corporation (TGT), the operator of general merchandise and food discount stores in the United States, posted its second-quarter 2012 results on August 15. Here we will discuss the companys scorecard, based on the recent earnings announcement, subsequent estimate revisions by analysts as well as the Zacks Rank and long-term recommendation for the stock. Last Quarter Synopsis Minneapolis, Minnesota-based company, Target, posted better-than-expected second quarter results on the backs of healthy sales. Lower shares outstanding also provided cushion to the bottom line. The company delivered quarterly earnings of $1.06 per share that rose 3.4% from $1.03 earned in the prior-year quarter, and also came ahead of the Zacks Consensus Estimate of $1.01. However, excluding costs related to Canadian operations, earnings from its U.S. operations came in at $1.12 per share, up 4.6% from $1.07 posted in the year-ago quarter. The quarterly earnings fit in with the companys previous projection of $1.04 to $1.14 per share. Total revenue climbed 3.3% to $16,779 million from the prior-year quarter, and beat the Zacks Consensus Estimate of $16,769 million. Retail sales grew 3.5% to $16,451 million as shoppers are gradually opening up their wallets but still remain wary. The company indicated that revenue from … Continue reading

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Drug peace

Posted: Published on August 22nd, 2012

Wise man: Author Doug Fine and his familiar HERBWISE Author Doug Fine's last book, Farewell My Subaru, is about the year he moved to a secluded New Mexico farm and attempted to live without petroleum. He's just as creative about advocating against the War on Drugs as is his against fossil fuel dependency -- for his new book Too High To Fail: Cannabis and the New Green Economic Revolution Fine spent a cannabis season living in a Mendocino grow town. He's been getting love from his recent appearance on Conan, but we caught up with him via email for some real talk while he was en route from his home, a.k.a. the Funky Butte Ranch, "hurtling toward live events in Colorado in an '87 RV." He'll be in town this week doing readings, so read up here and bring him questions to his Booksmith reading on Wed/22 and his event for cannabis patients at Harborside Health Center on Fri/24. SFBG: What are you adding to the discussion on cannabis legalization with Too High To Fail? Doug Fine: I relocated to Mendocino County, and for 10 months covered the county's successful efforts to permit sustainable cannabis farmers. I followed one flower … Continue reading

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Pharma Companies Switching Drugs to OTC Market

Posted: Published on August 22nd, 2012

By Tony Daltorio - August 21, 2012 | Tickers: AZN, GSK, PFE, RHHBY.PK, SNY | 0 Comments Tony is a member of The Motley Fool Blog Network -- entries represent the personal opinions of our bloggers and are not formally edited. Global pharmaceutical company AstraZeneca Group PLC ADR (NYSE: AZN) has suffered since late last year thanks to both expiring patents on key drugs and several developmental drug failures. The company has a much more substantial patent cliff than many of its peers with about half of its $33 billion in annual revenues expected to disappear by 2016. On the experimental drug side, it recently ended a second stage trial of CytoFab, a potential blockbuster drug treatment for sepsis, because it was found to be ineffective. In December, the company took a $382 million writedown on two other drugs that failed in late-stage trials. So AstraZeneca's management has to come up with different ways to generate revenues in order to remain a big player in the pharmaceutical sector. One strategy management is now following was on display recently with its deal with Pfizer (NYSE: PFE). AstraZeneca sold the global rights for an over-the-counter version of its leading (with $4.4 billion … Continue reading

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Thomson Reuters Study Confirms Economic Viability of Orphan Drugs Positioned for Unmet Medical Needs

Posted: Published on August 22nd, 2012

PHILADELPHIA, Aug.22, 2012 /PRNewswire/ --The Intellectual Property & Science business of Thomson Reuters, the world's leading provider of intelligent information for businesses and professionals, today released the results of its study on orphan drugs, developed to treat rare diseases, finding that they have the potential to generate as much lifetime revenue as drugs used for more common health conditions. The findings are featured in the Thomson Reuters paper, "The Economic Power of Orphan Drugs," and in Drug Discovery Today. Rare diseases affect from a handful to up to 200,000 patients and include illnesses such as Cystic fibrosis, Wilson's disease, and Homozygous familial hypercholesterolemia. (Photo:http://photos.prnewswire.com/prnh/20120822/NY61059-INFO) Life Sciences researchers at Thomson Reuters found that developmental drivers such as government incentives, shorter clinical trials and high rates of regulatory success make top orphan drugs as economically viable as non-orphan ones, even though the number of patients benefitting from them is significantly smaller than those benefitting from non-orphan medicine. "This new data gives economic validity to the importance of targeting rare diseases in the global pharmaceutical market," said Kiran Meekings, Ph.D., Life Sciences consultant at Thomson Reuters and co-author of the report. "Not only does such focus help those affected by rare diseases, of … Continue reading

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Almost 1 in 5 teens smokes or uses drugs at school, US students report

Posted: Published on August 22nd, 2012

Most high school students say teen use of alcohol, tobacco, or other drugs occurs during the school day, often on campus, according to an annual survey. They estimate that about 17 percent of their classmates do so. Eighty-six percent of American high school students report that some of their classmates use alcohol, tobacco, or other drugs during the school day. Subscribe Today to the Monitor Click Here for your FREE 30 DAYS of The Christian Science Monitor Weekly Digital Edition That's among the most significant findings of an annual survey of teenagers about their perceptions of drug use, released Wednesday, by the National Center on Addiction and Substance Abuse at Columbia University (CASAColumbia) in New York. The latest survey, the National Survey of American Attitudes on Substance Abuse XVII: Teens, gives parents a teen's-eye view of the relentlessness and pervasiveness of the school drug problem, says Joseph Califano Jr., founder and chairman emeritus of CASAColumbia and former US secretary of Health, Education, and Welfare. The survey gives a graphic portrait of what is going on in high schools and among high school students the fact that we have 9 out of 10 students saying that classmates are using drugs, drinking, … Continue reading

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London Drugs: Organizing Tips for Back-To-School

Posted: Published on August 22nd, 2012

RICHMOND, BRITISH COLUMBIA--(Marketwire -08/22/12)- Home organization is the key to keeping things under control throughout a busy school year. From back-to-school shopping to organizing student schedules, these tips and tricks will help your family make the transition from summer fun to back-to-school routines easier. Tip #1: Create a centralized, accessible family activities calendar The first step to creating a successful routine is having a clear picture of everyone's new schedules; classes, sporting events and additional extra-curricular activities. With so much going on, you'll want to create a home base where everyone can see what's happening at a glance. Using a simple paper wall calendar works well but there are now more high tech options that are particularly useful in households with older children. The Joy Factory Klick Wall Mount ($54.99) allows you to mount an iPad in a centralized location in the house so family members have easy access to enter their activities. This will also allow you to instantly sync family member's mobile devices, helping to keep everyone organized, on schedule and in the loop. Tip #2: Preserve memories, not junk As every parent knows, kids come home with a ton of papers and projects throughout the school year. … Continue reading

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Thomson Reuters Study Confirms Economic Viability of Orphan Drugs Repositioned for Unmet Medical Needs

Posted: Published on August 22nd, 2012

Orphan drugs achieve blockbuster status in 2011 and generate over $50 billion in revenue PHILADELPHIA, PA, August 22, 2012 - The Intellectual Property & Science business of Thomson Reuters, the world`s leading provider of intelligent information for businesses and professionals, today released the results of its study on orphan drugs, developed to treat rare diseases, finding that they have the potential to generate as much lifetime revenue as drugs used for more common health conditions. The findings are featured in the Thomson Reuters paper, "The Economic Power of Orphan Drugs" and in Drug Discovery Today. Rare diseases affect from a handful to up to 200,000 patients and include illnesses such as Cystic fibrosis, Wilson`s disease, and Homozygous familial hypercholesterolemia. Life Sciences researchers at Thomson Reuters found that developmental drivers such as government incentives, shorter clinical trials and high rates of regulatory success make top orphan drugs as economically viable as non-orphan ones, even though the number of patients benefitting from them is significantly smaller than those benefitting from non-orphan medicine. "This new data gives economic validity to the importance of targeting rare diseases in the global pharmaceutical market," said Kiran Meekings, Ph.D., Life Sciences consultant at Thomson Reuters and co-author … Continue reading

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Research and Markets: Ophthalmology Drugs And Devices (Diagnostic & Surgical) Market – Current Trends, Global …

Posted: Published on August 22nd, 2012

DUBLIN--(BUSINESS WIRE)-- Research and Markets (http://www.researchandmarkets.com/research/qtjwft/ophthalmology_drug) has announced the addition of the "Ophthalmology Drugs And Devices (Diagnostic & Surgical) Market - Current Trends, Global Forecasts & Pipeline Analysis to 2017" report to their offering. The global ophthalmology market witnessed a dip during the economic downturn in 2008 and 2009; however, it is poised to grow at a stable rate mainly due to an increasing aging population, large pool of patients with eye diseases, changing demographics and geographical trends, and increased focus on combination therapies of drugs. Moreover, incidences of glaucoma and cataract are increasing every year. Cataract is responsible for 48% of the population becoming totally blind. In addition, more than 60 million people suffer from glaucoma and this number is expected to reach 80 million by 2020. An increasing aging population is also resulting in more people suffering from refractive errors. It is estimated that in the U.S. and Europe, refractive errors affect more than 30% of the population aged 40 or older. However, the economic slowdown and drying pipeline of ophthalmology drugs is restricting the market. The ophthalmology drugs and devices market is divided into four major segments, namely, surgical devices, diagnostic and monitoring devices, vision care, and … Continue reading

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Trio breaks into pharmacy, steals drugs

Posted: Published on August 22nd, 2012

DEARBORN HEIGHTS Three men broke into Family Center Pharmacy and stole Vicodin, Xanax and cough syrup with codeine Friday morning. Police responded to a burglar alarm at the pharmacy, 4245 S. Beech Daly Road between Colgate and Stanford, at about 6:30 a.m. and found that the front outer glass door was pried open and that the inner door was smashed. The wooden door leading to the pharmacy was kicked in. A witness told police that he saw a black man pacing in front of the building and two black men leaving the building. The three ran north to Stanford and east on the neighborhood street, where they got into an dark Lincoln Mark VIII and drove west. Surveillance video showed two of the men pry open the outer door and try to pry open the inner door, but the glass shattered. The third man appeared on the video between the outer and inner doors. Both of the men who entered the pharmacy looked right at a surveillance camera. The pharmacys owner said she would give the security tape to police. Contact Staff Writer Joe Slezak at 1-734-246-0835 or jslezak@heritage.com. Follow him on Twitter @ JoeSlezak1. Police responded to a burglar … Continue reading

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