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InSightec Receives FDA Approval to Begin Phase I Parkinson's Trial

Posted: Published on August 21st, 2012

TIRAT CARMEL, Israel, August 20, 2012 /PRNewswire/ -- InSightec Ltd, the global leader in MR guided Focused Ultrasound (MRgFUS), announced that it has received approval from the US Food and Drug Administration (FDA) to begin a Phase I clinical trial evaluating the use of its ExAblate Neuro system for the treatment of patients with tremor dominant Parkinson's Disease. Thirty patients who suffer from medication-resistant tremor of Parkinson's Disease will be treated in a randomized control trial and followed up for one year. ExAblate Neuro, pioneered by InSightec, combines high intensity focused ultrasound for deep accurate lesioning of the brain, with continuous real-time MR guidance for visualizing brain anatomy, planning and monitoring treatment and outcome. The lesioning is performed through an intact skull with no incisions or ionizing radiation. The trial will be sponsored in collaboration with the Focused Ultrasound Foundation of Charlottesville, Virginia. The Foundation has established a brain program to define and help implement a comprehensive R&D roadmap for brain applications with MRgFUS. Lead investigator is Dr. Jeff Elias, MD, Director of Stereotactic and Functional Neurosurgery and Associate Professor of Neurological Surgery and Neurology, University of Virginia, Charlottesville, Va. Dr. Elias was recently the principal investigator of a Phase … Continue reading

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Jeff and Anne Keefer Give $1 Million to Penn's Parkinson's Disease & Movement Disorders Center

Posted: Published on August 21st, 2012

Philadelphia, PA The Penn Medicine Parkinsons Disease and Movement Disorders Center at Pennsylvania Hospital recently received a gift of one million dollars from Jeff and Anne Keefer of West Chester, PA. "The Parkinsons Disease and Movement Disorders Center (PD&MDC) is a leader in clinical research and the treatment of Parkinson's disease, said Mr. Keefer, a patient of the Center. I have received excellent care at the Center and both my wife Anne and I gave this gift because we want to see an acceleration of research to find disease modifying therapies and hopefully, eventually, a cure. We want to help the Center continue to make a difference in research and patients lives." The PD&MDC was established in 1982 at The Graduate Hospital (now Penn Medicine Rittenhouse at 18th and Lombard Streets) by Howard I. Hurtig, MD, chief of Neurology at Pennsylvania Hospital, co-director of the PD&MDC, and Elliott Professor of Neurology in the Perelman School of Medicine at the University of Pennsylvania, and Matthew B. Stern, MD, director of the PD&MDC and the Parker Family Professor of Neurology in the Perelman School of Medicine. Together Doctors Hurtig and Stern wanted to provide comprehensive care to patients with Parkinsons disease and … Continue reading

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Video: Younger Parkinson’s patients opt for surgical treatment

Posted: Published on August 21st, 2012

>>> in health news tonight we're going to talk about the 40,000 people diagnosed with parkinson 's disease every year in this country. a growing number of them are young, under age 50. more these days are turning to surgery to help keep their disease and symptoms at bay. tonight our chief medical editor dr. nancy snyderman has one remarkable success story. >> reporter: angela is a mother of four and a life-long runner. she used to start her days with a five- mile run , but lately her parkinson 's disease has made that and so much more impossible. >> i have little kids and they like to run around the yard. i would like to be able to keep up with them. >> reporter: angela is one of the estimated million americans living with parkinson 's disease a growing number under the age of 50. it is a degenerative disease which means it gets worse with time. >> that's me seven years ago just with one side. now it's switching over to both. >> reporter: she is off her medications because she has decided to try brain surgery to help her manage her disease and the surgery must … Continue reading

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Essex Chronicle published Honey Lock can now see clearly after treatment in US

Posted: Published on August 21st, 2012

SIX-year-old Honey Lock can finally see clearly after her parents raised 50,000 for a life-changing operation in America. Honey suffers from cerebral palsy and has grown up struggling to walk and see. But after donations from her local community, Honey's parents sent her to Missouri for treatment. HOME again: Honey Lock, 6, with sister Summer and mum Rebecca, has returned from America ALL SMILES: Burnham residents raised 50,000 for Honey Lock's operation in America. I CAN SEE YOU: Honey Lock can now see well after a life-changing operation. Her mother, Rebecca Lock of Dragon Close, Burnham, has just returned from the US with Honey and her other daughter, Summer. "Honey and Summer are still a bit jet-lagged but it's just fantastic that Honey is doing even better now. "It was a terrifying ordeal while we were out there but after having her second lot of orthopaedic surgery we can already see changes." Honey originally went out to St Louis Hospital in December last year and had Selective Dorsal Rhizotomy therapy, a treatment which allowed her to walk alone for the first time and involved four hours of spinal surgery. The second visit involved laser surgery on her eyes and more … Continue reading

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Doctors announce trial to cure autism with cord blood

Posted: Published on August 21st, 2012

Researchers announced Tuesday the beginning of a FDA-approved clinical trial that uses umbilical cord blood stem cells to cure autism. Dr. Michael Chez, director of pediatric neurology at Sutter Neuroscience Institute in Sacramento, Calif., said he and his colleagues have been processing the trial for more than a year now, and they have high hopes it will succeed. What we are looking at, is cases that dont have an obvious genetic link, Chez told FoxNews.com. Patients that we presume something went wrong with their brains, which caused a change to autistic features. In other words, the trials patients will essentially have no reason to have autism or at least no genetic markers for the disease. This means they must have presumably developed it through another factor, such as the environment or exposure to an infection. Inspired by Rydr Chez got the idea to treat autism with cord blood stem cells when he observed the cells radically cure a little boy who had cerebral palsy. Elisa Rudger of Sacramento, Calif., had a normal pregnancy but a difficult delivery. Her son, Rydr, was stuck for seven hours in the birthing canal, so doctors used a vacuum to remove him. At birth, he … Continue reading

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Herzog and Niesel: Reversing Cerebral Palsy

Posted: Published on August 21st, 2012

A child's symptoms can start with a weak or shrill cry, which seems normal enough. But then other problems appear, such as not being able to swallow or suck properly and having an overly floppy or stiff body. These are early signs of a group of disorders called Cerebral Palsy (CP), which is the No. 1 cause of motor disability in American children and affects over 11,000 new kids every year. Doctors treat the lifelong symptoms with physical therapy and drugs, but are unable to reverse the brain damage, which happens in the womb for most CP children. Now a study using a nanoparticle has successfully repaired damaged brains in rabbits with CP. A research team engineered a particle small enough to deliver anti-inflammatory drugs to overactive neurons in the brain that are killing healthy cells. Children with CP have varying types of brain damage due to genetic mutations, maternal infections that affect fetal brain development, lack of oxygen to the fetus or baby, or traumatic brain injury. In many of these cases, two types of immune cells in the brain become activated: microglia and astrocytes. They protect the brain during infection and inflammation, but damage the brain when they … Continue reading

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Neural interface for hand prosthesis can restore function in brain areas responsible for motor control

Posted: Published on August 21st, 2012

ScienceDaily (Aug. 20, 2012) Amputation disrupts not only the peripheral nervous system but also central structures of the brain. While the brain is able to adapt and compensate for injury in certain conditions, in amputees the traumatic event prevents adaptive cortical changes. A group of scientists reports adaptive plastic changes in an amputee's brain following implantation of multielectrode arrays inside peripheral nerves. Their results are available in the current issue of Restorative Neurology and Neuroscience. "We found that a neurally-interfaced hand prosthesis re-established communication between the central and peripheral nervous systems, not only restructuring the areas directly responsible for motor control but also their functional balance within the bi-hemispheric system necessary for motor control," says lead investigator Camillo Porcaro, PhD, of the Institute of Neuroscience, Newcastle University, Medical School, Newcastle upon Tyne, UK and the Institute of Cognitive Sciences and Technologies (ISTC) -- National Research Council (CNR). A 26-year old male with a left arm amputation was implanted with four microelectrode arrays in the ulnar and median nerves of his stump for four weeks. Prior to implantation, he was trained for two weeks by video to perform three specific movements with his phantom hand. During the experimental period, he underwent … Continue reading

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Baseline brain testing grows in popularity

Posted: Published on August 21st, 2012

Amid growing concerns about concussions, more student athletes are having their brain function tested prior to injury in a procedure called baseline testing that is becoming increasingly mainstream. Baseline tests can be used for comparison to neurological exams after an athlete suffers a concussion to help choose the best treatment. The tests, on the market for a few years, are used mostly by school athletic programs and collegiate and professional teams. This summer, HeadFirst began offering the test to patients at concussion centers in Gambrills and Annapolis. HeadFirst, an affiliate of Crofton-based Righttime Medical Care, uses the ImPact test. But even as use of the tests grows, some say the tests are unreliable and that athletes could be allowed to return to play before their concussions are fully healed. Parents who took their kids to the Gambrills center recently said they know the tests can't prevent concussions, but it gives them an added level of comfort. Tim Poole's son Sean, 13, is playing football for the first time this fall. When Poole heard about baseline testing while picking up his son's equipment, he quickly made an appointment for Sean. Poole used to coach basketball and remembers how frequently his players … Continue reading

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Settlement in MS suit over illegal workers

Posted: Published on August 21st, 2012

Crazy ants create nightmare for Hancock County residents Crazy ants create nightmare for Hancock County residents Updated: Monday, August 20 2012 6:52 AM EDT2012-08-20 10:52:49 GMT Updated: Friday, August 17 2012 12:04 PM EDT2012-08-17 16:04:27 GMT Updated: Tuesday, August 21 2012 6:54 AM EDT2012-08-21 10:54:09 GMT Updated: Friday, August 17 2012 2:44 PM EDT2012-08-17 18:44:29 GMT JACKSON, MS (AP) - Federal court records show a Mississippi company that was the target of the largest U.S. workplace raid on illegal immigrants has settled a discrimination lawsuit by four black women who claimed the company gave preferential treatment to Latinos. A tentative settlement was announced in February. Details were released in court documents filed this past week. U.S. District Court records show Howard Industries will pay $1.3 million into a settlement fund to be paid to possibly as many as 5,000 non-Hispanic individuals who applied for jobs at the company between March 2003 and Aug. 28, 2008. Also, within nine months after the settlement, the company will hire at least 70 of the individuals who had applied for jobs. Immigration agents detained nearly 600 illegal immigrants in the 2008 raid. Read more: Settlement in MS suit over illegal workers … Continue reading

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Local family holds Zumba fundraiser to battle MS

Posted: Published on August 21st, 2012

Heather Sinsels brother Robbie was diagnosed with multiple sclerosis (MS), an autoimmune disease that affects the brain and spinal chord, seven years ago at age 26. Ever since, she and her brother have participated in the MS Challenge Walk, among other MS fundraisers, including a mud run and the MS Walk held annually in Lenape Park in Perkasie. This is the first year hes not walking because hes not well enough, Sinsel said of her brothers health. Since she wont be able to walk with her brother, she decided to make a team of relatives and friends instead and deemed them Robbies Rockstars. So far, participants include Robbies aunt, Patricia DiPippa; his friend, Colleen Penglase; Sinsels friend, Robin Gilles; and, of course, Sinsel herself. Each year Sinsel has participated in the Philadelphia MS Challenge Walk, she has hosted a large fundrasing event. This year, she chose to have a fun morning of Zumba. Ditch the workout, join the party, is Zumbas tagline. The exercise form combines Latin and international music with dance moves that offer an effective full-body workout. Theresa Johnson, who teaches Zumba every Tuesday evening at St. Andrews Church at Dill and Chestnut streets in Perkasie, offered her … Continue reading

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