(CBS News) A male birth control pill advanced one step closer to reality, a team of cancer and fertility researchers announced Thursday after their latest discovery. Prescription drugs that lead double lives Sperm gene discovery may lead to male birth control, scientists say Scientists had been researching a small molecular compound called JQ1, which was meant to block a cancer-causing gene called "BRD4." The compound had previously been shown effective in staving off lung cancer and blood cancers, like leukemia and multiple myeloma, in earlier studies. Part of the problem with finding a male birth control pill is the challenge of getting a drug across the blood-testis barrier. Just like the blood-brain barrier regulates what cells and compounds come in and out of the brain, the blood-testis barrier physically separates blood vessels and the sperm-producing seminiferous tubules that are found in the testes. That's when Dr. James Bradner, an oncology researcher at the Harvard-affiliated Dana-Farber Cancer Institute in Boston who had been researching JQ1, wanted to see if the molecule was small enough to cross the blood-testis barrier. He was curious if the compound would affect the BRDT sperm-producing gene associated with that family of proteins he'd been researching for … Continue reading
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