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The battle to tackle drug addiction is not lost

Posted: Published on August 16th, 2012

The debate about legalisation is a distraction. Opium poppy buds in an Afghan field. Photograph: Getty Images It is impossible not to be moved by the plight of communities in Mexico and other drug-producing countries across the world. Crime and violence related to the supply of drugs are without a doubt causing extreme grief to citizens and governments. But reaching to decriminalise or legalise those drugs in the hope that it will overcome those communities deep-rooted problems offers them a false prospectus, and overlooks the nuanced picture of drug use and addiction which in this country at least, is in decline. For many producer nations, drugs are one of a number of complex factors contributing to adverse conditions within their countries. Legalisation would compound the devastating effects of drug use and the drugs trade, as former UN head of drugs and crime Antonio Maria Costa argues, especially if the structural issues that leave those states without the resources to tackle the causes and consequences of their drug problem are not addressed. The legal framework in this country does not prevent those with drug problems from being treated humanely and effectively. Drug treatment is freely and quickly available via the NHS … Continue reading →

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Commercializing Breast Cancer Drugs: The Faster Route to Consider Your Options and Position of Others

Posted: Published on August 16th, 2012

NEW YORK, Aug. 16, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: http://www.reportlinker.com/p0945797/Commercializing-Breast-Cancer-Drugs-The-Faster-Route-to-Consider-Your-Options-and-Position-of-Others.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_and_Medication This report will excel your competitive awareness and decrease your decision making time in managing breast cancer drug development. Find out whether you are number one, two or further down the ladder in this highly competitive market. Locate the right drugs to benchmark against and see were others may have succeeded or failed before you. This report comprises defined and up to date development strategies for 470 breast cancer drugs within the portfolio of 247 companies world-wide, from Ceased to Marketed. The report extensively analyses their 234 identified drug targets, organized into 223 drug target strategies, and assesses them in breast cancer. BioSeeker has applied its unique drug assessment methodology to stratify the breast cancer drug pipeline and discern the level of competition in fine detail. * The identified competitive landscape of breast cancer drugs is split between the approximately one third which have unique drug target strategies and the other two thirds which have head-to-head target competing drugs in 61 different clusters. The latter has a competing ratio which is almost two and a half times higher than … Continue reading →

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Personalized Medicine – A Global Market Overview

Posted: Published on August 16th, 2012

NEW YORK, Aug. 16, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: http://www.reportlinker.com/p0955290/Personalized-Medicine---A-Global-Market-Overview.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=In_Vitro_Diagnostic `Personalized Medicine can mean a lot of things to a lot of people. For some, it may relate to doctors having knowledge about their case history and the treatment received, which is a morale boosting factor, since everybody wants caregivers who can comprehend an individual's problems. The day is not very far when this level of personal or individual understanding between a patient and a doctor would be much deeper than hitherto anticipated. The coming decade is expected to witness an increase in the use of companion diagnostics and personalized medicines, with pricing incentives and efficiency improvement propelling the market. Current market leaders with diagnostic divisions focusing on biomarker identification would be at an advantage. This report review, analyze and projects the personalized medicine market for global and the regional markets including the United States, Europe and Rest of World. The market numbers illustrated in this report only represent the market exclusively for the product segments and technologies enunciated above. The market, in this report, does not include the associated hardware equipment or software technologies that are used to … Continue reading →

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Posted: Published on August 16th, 2012

The worlds first clinical safety trial of a human neural stem cell therapy for stroke patients has been given the go-ahead to progress to its next stage. The PISCES trial is being conducted by the University of Glasgow at the citys Southern General Hospital in partnership with pharmaceutical company ReNeuron. The Phase I trial is looking at the safety of injecting expanded neural stem cells, in increasing doses, into the brains of a total of 12 patients left disabled by an ischaemic stroke, the most common form of the condition, and monitoring them over a period of two years. The independent Data Safety Monitoring Board (DSMB) for the clinical trial has recommended the trial advances to the evaluation of a higher dose of stem cells in the third of four dose cohorts to be treated in the study. In arriving at this recommendation, the DSMB reviewed safety data from the first two dose cohorts of six patients treated with ReNeurons ReN001 stem cell therapy. Of these patients, two are through 18 month follow-up, one is through 12 month follow-up, one is through 9 month follow-up, one is through 6 month follow-up and one is through three month follow-up. No cell-related … Continue reading →

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World First: Islet Transplant Into Man Using Sernova's Cell Pouch(TM) for Treatment of Diabetes

Posted: Published on August 16th, 2012

LONDON, ONTARIO and EDMONTON, ALBERTA--(Marketwire - Aug. 16, 2012) - Sernova Corp. ("Sernova" or the "Company") (SVA.V) and the University of Alberta today announced the treatment of the first patient with insulin-producing islets transplanted into Sernova's Cell Pouch(TM) in a Phase I/II clinical study to treat Type-1 diabetes led by Dr. James Shapiro, Professor of Surgery and Medicine, University of Alberta and Director, Clinical Islet Transplant Program. Sernova will host a conference call at 9 a.m. EDT, today, Aug. 16, 2012, to discuss the company's clinical and business developments. "The Sernova Cell Pouch(TM) implantation and transplantation processes are simple, rapid minimally invasive procedures, conducted on an outpatient basis under local anesthesia," said Dr. Shapiro. "This offers substantial potential benefit over the Edmonton protocol and the ease of use provides an opportunity for the Cell Pouch(TM) to become the standard of care for people with diabetes if it proves to be effective in these initial trials." The objectives of the human clinical trial are to assess the safety and efficacy of the Cell Pouch(TM) with transplanted islets in up to 20 patients with Type-1 diabetes. The study is sponsored by Sernova Corp and the University of Alberta. In the study, patients … Continue reading →

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Stroke screening offered to Newton area residents

Posted: Published on August 16th, 2012

Everyone has risk associated with Stroke. Knowing your risk and getting a fast and painless stroke screening are your best defenses against a life threatening or life-altering event. Many people go through their daily routines without realizing how close they are to suffering a lifethreatening stroke. And, unfortunately, most people dont have symptoms or signs before a stroke occurs. Thats why stroke is commonly referred to as the silent killer, ranking as the third leading cause of death in the United States. But new mobile technology is available today to help individuals determine their stroke risk in advance so they can take steps to improve their health. A stroke screening will help to identify these blood flow blockages. Stoke Detection Plus, a mobile vascular screening company, uses ultrasound technology to find blockages in the bodys blood vessels that could lead to a stroke. Ultrasound technology is something thats been around for over 50 years. Medical professionals have used the visual, non-invasive technology in many applications. Pregnancy is probably the most well-known application of ultrasound, says Scott McGlothlen, Stroke Detection Plus President. Ultrasound can also help doctors see blocked blood vessels without performing an angiogram, an invasive procedure in which a … Continue reading →

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Therapy combining exercise and neuroprotective agent shows promise for stroke victims

Posted: Published on August 16th, 2012

ScienceDaily (Aug. 15, 2012) In a study published in the current issue of Restorative Neurology and Neuroscience, scientists report that a therapy combining exercise with the neurovascular protective agent S-nitrosoglutathione (GSNO) improved recovery from stroke in a rat model. GSNO is a compound found naturally in the body and it has no known side effects or toxicity. "In our study, GSNO or motor exercise provided neuroprotection, reduced neuronal cell death, maintained tissue structure, and aided functional recovery by stimulating the expression of neuronal repair mediators," says lead investigator Avtar K. Singh, MD, of the Medical University of South Carolina (MUSC) and the Ralph H. Johnson VA Medical Center, Charleston. "GSNO in combination with exercise accelerated the rate and enhanced the degree of recovery." Stroke is both an acute disease and a chronic condition. While the acute phase is associated with cell death and secondary injury, the chronic phase is characterized by insufficient neurorepair mechanisms. Most monotherapies fail because the drugs are not effective in the chronic phase. Rehabilitation has been used to improve neurofunction in the chronic phase, but its efficacy is slow and limited. An ideal therapy would ameliorate the injury in both phases and therefore include a combination … Continue reading →

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Are Gaucher Disease and Parkinson's Linked?

Posted: Published on August 16th, 2012

The NIH Is Investigating a Possible Connection Courtesy of Ted Meyer Richard Meyer: The New York folk singer had Gaucher; he died in June of Parkinsons disease. His brother Ted Meyer undergoes brain imaging and other tests as part of the NIH study. Ted Meyer was six years old the first time he got involved in medical research, by donating a sample of bone marrow. He had just been diagnosed with Gaucher disease, and his parents hoped their sons participation might help him and others with the potentially fatal inherited metabolic disorder. Meyer, 54, is still actively participating in Gaucher research though it has taken an unexpected turn in the past few years. The Los Angeles-based artist is part of a federally funded study at the National Institutes of Health (NIH) aimed at understanding a genetic link between Gaucher, a rare disease that disproportionately affects Jews of Ashkenazi descent, and Parkinsons disease, a progressive movement disorder that affects more than 1.5 million older Americans. Meyers brother Richard, who was likewise diagnosed with Gaucher as a child, went on to develop Parkinsons in his late 40s. Richard Meyer, a New York City-based folk singer, died in June at the age of … Continue reading →

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Chinese researcher tries new treatment for Parkinson’s disease

Posted: Published on August 16th, 2012

A Chinese researcher is testing a new way to treat Parkinsons disease by transplanting neural cells from pigs into the brains of Parkinsons-affected monkeys. Experimental results showed that Parkinsons disease in the participating monkeys was well controlled after they received the neural transplants. Reuters pic Wang Wei, a medical professor at the Third Xiangya Hospital affiliated with Central South University in central Chinas Hunan province, said his method of transplanting neural cells from pigs into the brains of Parkinsons-affected monkeys aroused interest among scientists at the International Congress of the Transplantation Society held in Berlin, Germany in July. Xenotransplantation, according to Wang, refers to the transplantation of living cells, tissue or organs from one species to another. Experimental results showed that Parkinsons disease in the participating monkeys was well controlled after they received the neural transplants, Wang said. This indicates that the treatment of Parkinsons disease through xenotransplantation has seen initial success, Wang said in a statement posted on the website of Central South University. The neural cells of pigs are covered in a semi-permeable membrane, enabling transplanted cells to function properly while avoiding immune system rejection by recipients, Wang added. Our next step is to solve safety problems regarding … Continue reading →

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Essex Chronicle published George is feeling fitter after operation to ease his cerebral…

Posted: Published on August 16th, 2012

RIDING a bike for the first time George Balding is thriving after an operation to ease his cerebral palsy. The eight-year-old was diagnosed with the condition at just 15 weeks old, after he was born prematurely at St John's Hospital, weighing just three pounds and two ounces. FIGHTING FIT: Vikki and Jamie Balding with son George The Chronicle has followed his story since September last year when his parent's announced plans to raise 45,000 to send him to America for treatment. He returned earlier this year and is relatively fit. He is no longer in pain and can sit, stand flat-footed and ride a bike. His mother Vikki Balding said: "George's progress has been consistent and amazing. "George still has problems with his right hip which is 50 per cent uncovered and will need to be corrected in February next year. "We are so grateful to everyone for all they did to help with the fundraising they all helped to change George's life forever. "He is getting stronger every day and although we are not fundraising anymore, we are really busy keeping up with George's daily exercises." Original post: Essex Chronicle published George is feeling fitter after operation to ease … Continue reading →

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