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Drug Could One Day Treat Parkinson's

Posted: Published on August 9th, 2012

ATLANTA Scientists at Georgia Health Sciences University in Augusta have identified a drug that could one day be a potent treatment for Parkinsons disease. The research used a new kind of antioxidant to prevent the diseases development. Neuroscientist Bobby Thomas and his colleagues targeted a substance in the body called Nrf2 that fights oxidative stress and inflammation. They used powerful new antioxidants to keep Nrf2 from degrading so it can trigger genes that control that inflammatory response. Basically, it can prevent the induction of oxidative stress and also exacerbated inflammation, which we clearly see in Parkinsons, Thomas said. Thomas says patients with Parkinsons have an overload of this oxidative stress and the bodys response inflammation which can lead to the death of brain cells that produce dopamine. So by regulating that response with the new drugs, they were able to prevent development of the disease in animal models. The researchers tested the drugs on cells that developed Parkinsons-like damage within days in the lab. Now theyre testing them on animal models that are genetically programmed to develop the disease more slowly, like humans do. Thomas says its the first time this new class of antioxidants has been tested on Parkinsons-like … Continue reading →

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Brain damaged and facing a life of round-the-clock care – but 5 star hotel where British newlywed was terribly injured …

Posted: Published on August 9th, 2012

By Tahira Yaqoob PUBLISHED: 11:51 EST, 9 August 2012 | UPDATED: 13:29 EST, 9 August 2012 Since the accident Natalie Creane has been drifting in and out of coma in intensive care A British newlywed left with a life-threatening brain injury after a TV panel fell on her head in a five-star hotel needs round-the-clock care, her family told a court today. Natalie Creane, 33, cannot be left alone after the incident in the Emirates Palace Hotel in Abu Dhabi left her suffering epileptic seizures and a traumatic brain injury, her husband Trevor said. He was summonsed by a judge to give evidence in Abu Dhabi Higher Civil Claims Court as part of her 3.5 million compensation claim against the hotel, which has denied responsibility and disputed her version of events. But according to court records, the hotel used pictures of her wedding from her Facebook page to disprove her claims. It stated: 'We have presented evidence showing she has continued with her lifestyle as normal.' The statement added the claim was 'a figment of the claimant's imagination' and said it has supplied photos of the wardrobe and the panel that was said to have fallen, adding as it weighed … Continue reading →

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ViroPharma Incorporated Reports Second Quarter 2012 Financial Results

Posted: Published on August 9th, 2012

EXTON, Pa., Aug. 9, 2012 /PRNewswire/ --ViroPharma Incorporated (VPHM) reported today its financial results for the second quarter ended June 30, 2012. Since March 31, 2012, we: Net sales were $94.6 million for the second quarter ended June 30, 2012, as compared to $128.8 million in the comparative period of 2011. The decrease was the result of the impact of generic oral vancomycin entries into the market. Regarding Cinryze, the channel remained below normal levels from the end of the first quarter and as a result, the revenue reported is more reflective of demand. The company anticipates that the levels of channel inventory will increase in the third and fourth quarters as additional Cinryze begins to enter the market. Net sales were $230.4 million for the six months ended June 30, 2012, as compared to $255.8 million in the comparative period of 2011. "The second quarter of 2012 represents the new base from which all of our future growth as a company will be measured," stated Vincent Milano, ViroPharma's chief executive officer. "The positive momentum we experienced during the period bodes well for the trajectory of our growth. With the recent expansion in manufacturing capacity, continued strong patient adds and … Continue reading →

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Summer school students help scientists advance stem cell research at USC

Posted: Published on August 9th, 2012

Listen Now [4 min 28 sec] Listen Now [4 min 28 sec] For many Southern California high school students, summer is synonymous with surf, sand and sun. But, for some of Los Angeles' top math and science students, the lure of the beach and traditional summer fun fizzles fast when compared to microscopes, slide kits and real-life stem cell research. Armed with little more than protective gear and enthusiasm, 20 overachieving teenagers have been clocking 40-hour weeks in the lab at USC's Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research. Among them is 17-year-old Brian Tom of Lincoln Heights. Its fascinating because stem cells have all this potential to heal these degenerative diseases like Multiple Sclerosis and Alzheimer's," says Tom, a senior at Bravo Medical Magnet in Los Angeles. "It's amazing how you can create multiple tissues from one cell." Stem cells offer promise as a treatment or cure for many diseases because they can be can induced to morph into other cell types such as brain, muscle or skin cells. Stem cells can also divide without limit, which gives them the potential to repair and replace damaged tissue. You can just imagine the possibilities," says … Continue reading →

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Scientists find the stem cells that drive our creativity

Posted: Published on August 9th, 2012

Researcher find master cells also key for abstract thought and planning ahead Breakthrough could lead to new treatments for autism By Mark Prigg PUBLISHED: 13:00 EST, 9 August 2012 | UPDATED: 13:00 EST, 9 August 2012 A newly-discovered type of stem cell could be the key to higher thinking in humans, research suggests. Scientists have identified a family of stem cells that may give birth to neurons responsible for abstract thought and creativity. The cells were found in embryonic mice, where they formed the upper layers of the brains cerebral cortex. Researchers hope the breakthrough could lead to new treatments for disorders such as autism In humans, the same brain region allows abstract thinking, planning for the future and solving problems. Previously it was thought that all cortical neurons - upper and lower layers - arose from the same stem cells, called radial glial cells (RGCs). The new research shows that the upper layer neurons develop from a distinct population of diverse stem cells. View original post here: Scientists find the stem cells that drive our creativity … Continue reading →

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Neuroscientists find brain stem cells that may be responsible for higher functions, bigger brains

Posted: Published on August 9th, 2012

ScienceDaily (Aug. 7, 2012) Scientists from The Scripps Research Institute have identified a new stem cell population that may be responsible for giving birth to the neurons responsible for higher thinking. The finding also paves the way for scientists to produce these neurons in culture -- a first step in developing better treatments for cognitive disorders, such as schizophrenia and autism, which result from disrupted connections among these brain cells. Published in the August 10, 2012 issue of the journal Science, the new research reveals how neurons in the uppermost layers of the cerebral cortex form during embryonic brain development. "The cerebral cortex is the seat of higher brain function, where information gets integrated and where we form memories and consciousness," said the study's senior author Ulrich Mueller, a professor and director of the Dorris Neuroscience Center at Scripps Research. "If we want to understand who we are, we need to understand this area where everything comes together and forms our impression of the world." In the new study, Mueller's team identified a neural stem cell in mice that specifically gives rise to the neurons that make up the upper layers of the cerebral cortex. Previously, it was thought that … Continue reading →

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International Stem Cell Corp Announces Second Quarter 2012 Financial Results

Posted: Published on August 9th, 2012

CARLSBAD, CA--(Marketwire -08/09/12)- International Stem Cell Corporation (ISCO) (www.internationalstemcell.com) ("ISCO" or "the Company"), a California-based biotechnology company focused on therapeutic and research products, today announced financial results for the three and six months ended June 30, 2012. Three and Six Months Ended June 30, 2012 Revenue for the three months ended June 30, 2012 totaled $1.06 million compared to $1.11 million for the three months ended June 30, 2011. The decrease in revenue was due largely to lower sales generated from Lifeline Cell Technology (LCT). LCT and Lifeline Skin Care (LSC) each accounted for approximately 50% total revenue in the three months ended June 30, 2012 compared to 52% and 48%, respectively, in the corresponding periods the prior year. Revenue for the six months ended June 30, 2012 was $2.13 million compared to $2.63 million for the corresponding period in 2011. The decrease in revenue was due principally to fewer sales generated from LSC, partially offset by LCT's higher sales generated from larger distributors. For the six months ended June 30, 2012, LSC generated $1.07 million or 50% of total revenue, compared to $1.66 million or 63% of total revenue for the corresponding period in 2011. For the six months … Continue reading →

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Olympic Horse Used Stem Cell Therapy

Posted: Published on August 9th, 2012

Ravel, a horse competing at the 2012 London Olympics, underwent stem cell therapy treatment that helped heal a possibly career-ending injury to one of his legs, according to the Helen Woodward Animal Center in California. Ravel, a regular client of Rodrigo Vazquez of Equine Surgical Services at the center, is believed to be the first Olympian to benefit from a stem cell-based treatment. Ravel is now the highest scoring horse on Team USA at the Olympics. "Ravel is a high-impact athlete," Vazquez said. "He runs the same risks as any other athlete in a high performance sport and he gets hurt like any other athlete too. But he is something special. He works hard and he's focused and he thrives in his sport. He just didn't want to quit." The 15-year-old equine athlete, owned by Akiko Yamazaki, was united with his rider Steffen Peters in late 2006. Since then, the team has made history, with Ravel excelling in dressage, which is one of three Olympic equestrian disciplines. It involves riding and training a horse in a manner that develops obedience, flexibility and balance. Ravel and Peters were the highest placing American pair at the 2008 Beijing Olympics, and have won … Continue reading →

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Can liposuction help you live longer?

Posted: Published on August 9th, 2012

TUCSON, Ariz., Aug. 9, 2012 /PRNewswire/ -- Doctors at the University of Oklahoma reported the first successful procedure for growing new blood vessels from adipose, or 'fat derived,' stem cells. These newly formed blood vessels can be used in heart bypass surgery and other complicated procedures requiring healthy vessels, according to the researchers, who presented their findings at the American Heart Association's 2012 Scientific Sessions. (Photo: http://photos.prnewswire.com/prnh/20120809/LA54820) Through liposuction, doctors can collect hundreds of millions of stem cells that can be used to generate blood vessels. The cells were "seeded" onto a 'bio-scaffold' and as they multiplied, researchers rolled them into tubes with the diameter of small blood vessels. Within weeks, new, healthy tissue began to grow into usable blood vessels. And since the cells are 'autologous', or from the same patient, there is no risk of adverse reactions or rejection. But one of the key considerations is the age of the patient and thus the age of the stem cells. Young stem cells are much more active and potent than older cells. And young blood vessels are much more functional than older vessels. One potential downside is that these blood vessels take time to grow in the lab. "They … Continue reading →

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Advanced Cell Technology Announces 2012 Second Quarter Results

Posted: Published on August 9th, 2012

MARLBOROUGH, Mass.--(BUSINESS WIRE)-- Advanced Cell Technology, Inc. (ACT, OTCBB: ACTC)(the Company), a leader in the field of regenerative medicine, announced today second quarter financial results for the period ended June 30, 2012. Highlights of the second quarter include: Second Quarter 2012 Financial Results ACT had revenue totaling $218,184 for the 2012 second quarter, compared to revenue of $153,688 in the prior year. Revenue was generated through license fees and royalty payments. Research and Development expenses for the three months ended June 30, 2012 and 2011 were $2,068,098 and $1,532,271 respectively. The Company reported a loss from operations of $(4.5) million in the 2012 second quarter compared to a loss from operations of $(3.6) million in the 2011 second quarter. ACT reported a net loss of $(4.0) million or $(0.00) loss per share in the 2012 second quarter, compared to a net loss in the same period of 2011 of $(4.8) million, or $(0.0) per share. Net cash used in operations for the 2012 second quarter was $2.9 million, compared to net cash used in operations of $3.3 million in the same period in 2011. The net cash used in operations was a result of ongoing clinical activities. The Company ended … Continue reading →

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