As expected, the FDA recently announced approval of a second drug for obesity within a month, Vivus Qnexa, now renamed Qsymia. This approval is less of a surprise, as the data appeared somewhat stronger than that for Arenas lorcaserin (Belviq). What was rather curious is that USA Today broke news of the drugs approval before the FDA had announced their decision. The FDA is responding to the growing crisis of obesity. As noted in my post, A Glut of Obesity Drugs? the Centers for Disease Control and Prevention has established that more than one-third of adults in the United States are obese, defined as having a Body-Mass Index of > 30. In the U.S. alone, 78 million U.S. adults are obese; another 34% of adults are overweight > 25-29. So 70% of US adults have a problem with weight. This results in an estimated 300,000 deaths per year. And the burden of obesity is increasing, expected to rise to 42% by 2030, with an additional 11% prevalence of severe obesity (BMI >40, or ~80+ lbs overweight). Obesity is the second cause of preventable deaths, after smoking. The costs of obesity are also staggering, and may be as high as $147 … Continue reading
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