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Caffeine may ease Parkinson's symptoms, suggests research

Posted: Published on August 2nd, 2012

Caffeine consumption may help control movement in people suffering from Parkinson's, according to new research. Consumption of caffeine could reduce the symptoms of Parkinson disease by aiding control of movement, say the researchers. The study published in Neurology investigated the effects of caffeine on Parkinson disease symptoms, noting that whilst epidemiologic studies have consistently linked caffeine consumption to a lower risk of the disease, research into the symptomatic effects of caffeine in Parkinsons have not been adequately evaluated. "This is one of the first studies to show the benefits of caffeine on motor impairment in people who have Parkinson's disease," said Dr Ronald Postuma, lead author of the study. "Research has already shown that people who drink coffee have a lower risk of developing Parkinson's disease, but until now no study had looked at the immediate clinical implications of this finding," said the lead researcher, who is based at McGill University, Canada. This is one of the first studies in humans to show that caffeine can help with movement symptoms for people who already have the disease." Postuma noted that the results of the study open the door to potential new therapies for the symptoms of Parkinsons. Wake-up call? Caffeine … Continue reading →

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Caffeine helps Parkinson’s patients move: study

Posted: Published on August 2nd, 2012

Drinking coffee may help people with Parkinsons disease move with greater ease, although getting steady jolts of caffeine doesnt appear to alleviate the daytime sleepiness that affects certain patients, a study suggests. In the Canadian-led study, researchers set out to see if caffeine could help overcome whats called daytime somnolence, a symptom that affects some patients with the progressive neurological disease. While they didnt find an appreciable wake-up effect among subjects taking caffeine, the researchers were surprised to find that javas main ingredient appeared to enhance patients mobility. What was significant was the movement improvement, said principal investigator Dr. Ronald Postuma, a neurologist at McGill University Health Centres research institute. And this was present both on motor symptoms, but also on the objective scoring in the motor exam. To conduct the study, 61 people with Parkinsons disease who showed symptoms of daytime sleepiness and some motor impairment were randomly assigned to receive either a placebo pill or a caffeine tablet. Participants chosen for the study were not big coffee drinkers on average, they drank only about one cup per day. Those in the treatment group took a pill containing 100 milligrams of caffeine twice daily for three weeks, then 200 … Continue reading →

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Cerebral palsy boy never gives up Save

Posted: Published on August 2nd, 2012

Aug. 2, 2012, 11:46 a.m. DANIEL Fairclowgh has never let cerebral palsy stop him doing what he loves and is encouraging those with the condition to do the same and never give up. National Cerebral Palsy Awareness Week, from July 30 to August 5, is an opportunity for the strength and needs of people like Daniel to be put in the spotlight. Daniel was born with the physical condition which affects the movement on the left-hand side of his body. Having the condition causes the Falcon Primary School student to experience weakness, stiffness and sometimes involuntary movements which can often cause tightness and pain in his left arm. Daniels mum Sandra Lavender said she first noticed something was wrong when he was four months old and his left hand seemed to be clenched. At six months Daniel was diagnosed with dystonic hemiplegia which is the most common form of cerebral palsy affecting more than one million children under 21 worldwide. For most people with cerebral palsy the cause is unknown but Ms Lavender said it can be caused by lack of oxygen to the baby's brain before or during pregnancy. According to the Cerebral Palsy Alliance the most common cause … Continue reading →

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Rural/Metro Announces Multi-County Arizona Epic-Traumatic Brain Injury Agency Certification

Posted: Published on August 2nd, 2012

SCOTTSDALE, AZ--(Marketwire -08/02/12)- Rural/Metro Corporation announced today that its family of companies in Arizona -- Southwest Ambulance, PMT Ambulance, Rural/Metro Fire Department and Rural/Metro Ambulance -- have received Excellence in Prehospital Injury Care (EPIC)-Traumatic Brain Injury certification for prehospital care by the Arizona Department of Health Services (ADHS). The Company's entire emergency medical services (EMS) work force in Arizona is trained to the highest prehospital treatment protocols for victims of traumatic brain injuries in accordance with ADHS' EPIC program. Rural/Metro is the only private ambulance provider in Arizona trained to the highest state standards in multiple counties (Maricopa, Pinal, Pima and Yuma). Southwest Ambulance, PMT Ambulance, Rural/Metro Fire Department and Rural/Metro Ambulance provide emergency medical services to 84% of the state's population in Maricopa, Pima, Pinal and Yuma counties. Michael P. DiMino, President & Chief Executive Officer, said, "As a national leader in EMS, our commitment to clinical excellence in every aspect of our business drives us each day to perform to the highest standards in every community we serve. These standards are proven to contribute to positive patient outcomes and provide our receiving hospitals with every prehospital advantage possible when we bring patients into their emergency departments." Each year, … Continue reading →

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Chief Minister denies French deception

Posted: Published on August 2nd, 2012

Chief Minister Katy Gallagher has confirmed she met the woman behind the Canberra Hospital data tampering scandal during a 2010 holiday in France. In April the staffer admitted changing data to make treatment times in the emergency department look better. She has since resigned. Ms Gallagher says while on leave she stayed with her her sister in France, who was also on holiday there. Ms Gallagher says the staffer, a friend of her sister, also visited. "I have provided all of this information to the Auditor General. I have provided this information to the Solicitor General and I sought advice around how to handle this going forward and from my point of view I've made that information clear," she said. "The investigation has happened and it's cleared me of any involvement in any direct or indirect way and I think that gets lost in all of this." But the ACT Opposition has accused the Chief Minister of deceiving the public. Liberal's Jeremy Hanson says Ms Gallagher has not been up-front. "Why was she hiding this personal relationship? What else is there that Katy Gallagher hasn't told us about this scandal?" he said. See the original post: Chief Minister denies French … Continue reading →

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Repligen Announces Strategic Focus on Bioprocessing Business and Reports Second Quarter 2012 Financial Results

Posted: Published on August 2nd, 2012

WALTHAM, Mass.--(BUSINESS WIRE)-- Repligen Corporation (RGEN) today reported financial results for its second quarter and year-to-date period ended June 30, 2012. In addition, the Company announced that it will focus its corporate strategy and resources on the growth of its core bioprocessing business, which achieved record sales during the quarter. As a result of this defined strategic focus, the Company will seek a development and commercialization partner for its pancreatic imaging product candidate, RG1068. The Company reported total revenue for the three-month period ended June 30, 2012 of $15,524,000 compared to $7,654,000 for the same period in 2011. Revenue growth for the second quarter of 2012 was driven by the Companys expanded bioprocessing business, which generated $11,659,000 in product revenue compared to $4,358,000 for the same period in 2011, an increase of 168%. Royalty and research revenue for the three-month period ended June 30, 2012, consisting primarily of royalty payments from Bristol-Myers Squibb on its U.S. sales of Orencia, was $3,865,000 compared to $3,295,000 for the same period in 2011. June 30, 2012 marks the end of the second fiscal quarter for which the Company is reporting consolidated financial results since its acquisition of Novozymes Biopharma Sweden AB (now Repligen … Continue reading →

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BioLife Cell Bank and Intrexon Establish Worldwide Exclusive Collaboration for Spinal Muscular Atrophy (SMA)

Posted: Published on August 2nd, 2012

DALLAS and GERMANTOWN, Md., Aug. 2, 2012 (GLOBE NEWSWIRE) -- BioLife Cell Bank, Inc., the leader in cryogenic storage of adipose (fat) tissue and adult mesenchymal stem and regenerative cells, and Intrexon Corporation, a synthetic biology company that utilizes its proprietary products to provide control over cellular function, announced today the formation of a global exclusive research collaboration. Under the collaboration, BioLife, with its extensive physician network and stem cell experience coupled with Intrexon's innovative technology, will strive to produce new treatments for Spinal Muscular Atrophy (SMA). "With the tremendous potential of this collaboration, we are more than excited for the SMA community," said John A. Carbona, Chief Executive Officer of BioLife. "Intrexon's impressive suite of technologies will give researchers access to unprecedented resources including new techniques and processes which could rapidly propel us toward the development of new treatments and products to help treat children with SMA." Carbona continued, "I am happy to help realize the dream of our founders, Dr. David G. Genecov and John D. Harkey Jr., to make a positive and sustainable impact in health care. We're elated by our new collaboration with Intrexon and will undertake immediately the establishment of relationships with the world's leading … Continue reading →

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Cancer Stem Cells May Drive Tumor Growth

Posted: Published on August 2nd, 2012

Featured Article Academic Journal Main Category: Cancer / Oncology Also Included In: Stem Cell Research;Biology / Biochemistry Article Date: 02 Aug 2012 - 2:00 PDT Current ratings for: Cancer Stem Cells May Drive Tumor Growth 4.25 (4 votes) Papers on all three studies appeared online on Wednesday, two in Nature and one in Science. In all three studies, the teams used genetic cell-marking techniques to track cell lineage and show that a restricted cell population appears to be the source of new tumor cells, in much the same way as stem cells are the "master builders" of new healthy cells. GBM is a type of brain cancer that is currently considered incurable. It is a fast-growing tumor with a median survival of about 15 months. Although initially it responds to chemotherapy, the cancer nearly always comes back. In their study, Parada and colleagues used genetically engineered mice bred to develop GBM and found that the resting tumor cells act more like stem cells. They used a genetic marker that labels healthy adult neural stem cells, but not their more specialized descendants, to see if it would do the same for cancer stem cells in GBM. When they did so, they … Continue reading →

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Stem cell findings point toward new cancer treatments

Posted: Published on August 2nd, 2012

When cancers are treated, tumors may shrink but then come roaring back. Now studies on three different types of tumors suggest a key reason why: The cancers are fueled by stem cells that chemotherapy drugs don't kill. The findings made by independent research teams that used mice to study tumors of the brain, intestines and skin could change the approach to fighting cancers in humans, experts said. Properties of these so-called cancer stem cells can be investigated so researchers can devise strategies for killing them off, said Luis F. Parada, a molecular geneticist at the University of Texas Southwestern Medical Center in Dallas and senior author of one of the studies published Wednesday. "Everything has a soft underbelly once you understand it well," Parada said. "With all the modern molecular techniques and modern approaches we have, we should be able to find their soft underbelly." Cancer researchers have long suspected and some pioneering studies have strongly suggested that specific cells within tumors are responsible for their continued growth. But the earlier experiments hadn't convinced everyone, and the hypothesis has been controversial. The three papers published by the journals Nature and Science "really should seal the deal," said cancer biologist Owen … Continue reading →

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Biostem U.S., Corporation Scientific and Medical Board of Advisors Member Appointed Chief of Cardiothoracic Surgery at …

Posted: Published on August 2nd, 2012

CLEARWATER, FL--(Marketwire -08/02/12)- Biostem U.S., Corporation, (HAIR) (HAIR) (Biostem, the Company), a fully reporting public company in the stem cell regenerative medicine sciences sector, Chief Executive Officer Dwight Brunoehler stated, "Dr. Prendergast is a very talented and very active clinical and research surgeon. Biostem is fortunate to have his guidance in our scientific and medical pursuits. He will be playing an ever increasingly important role in the company's future regarding the use of stem cells and regenerative medicine." According to Dr. Prendergast, "The Robert Wood Johnson Medical School currently has several stem cell related projects including the use of stem cells to reduce the risk of kidney related dysfunction following cardiac surgery. As Biostem grows, I look forward to assisting in implementing the Company's stem cell regenerative medicine goals in multiple areas." Dr. Prendergast is a clinical cardiothoracic surgeon, who performs 200-250 open-heart operations and 5 to 15 heart transplants each year. He is deeply involved in numerous clinical and research activities associated with stem cells and heart repair. He is presently Director of Cardiac Transplantation at Robert Wood Johnson University Hospital in New Brunswick, New Jersey, where he holds an Associate Professorship of Surgery at the University of Medicine … Continue reading →

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