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CHOC Children’s Research Project Awarded $5.5 Million Grant from the California Institute for Regenerative Medicine

Posted: Published on May 30th, 2012

ORANGE, Calif.--(BUSINESS WIRE)-- A CHOC Childrens research project, under the direction of Philip H. Schwartz, Ph.D., senior scientist at the CHOC Childrens Research Institute and managing director of the facilitys National Human Neural Stem Cell Resource, has been awarded a $5.5 million grant from the California Institute for Regenerative Medicine (CIRM). The grant will be used to develop a stem cell-based therapy for the treatment of mucopolysaccharidosis (MPS I), a fatal metabolic disease that causes neurodegeneration, as well as defects in other major organ systems. Based on a number of medical and experimental observations, children with inherited degenerative diseases of the brain are expected to be among the first to benefit from novel approaches based on stem cell therapy (SCT). Dr. Schwartz explains, While uncommon, pediatric genetic neurodegenerative diseases account for a large burden of mortality and morbidity in young children. Hematopoietic (bone marrow) stem cell transplant (HSCT) can improve some non-neural symptoms of these diseases, but does not treat the deadly neurodegenerative process. Our approach targeting the effects of the disease on organs besides the brain with HSCT and neurodegeneration with a second stem cell therapy specifically designed to treat the brain is a strategy for whole-body treatment of … Continue reading

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New Personalized Medicine for ALK-positive Advanced or Metastatic Non-small Cell Lung Cancer

Posted: Published on May 30th, 2012

XALKORI NOW AVAILABLE IN CANADA KIRKLAND, QC, May 30, 2012 /CNW/ - Pfizer Canada is pleased to announce that XALKORI (crizotinib) is now available in Canada. Recently approved with conditions by Health Canada, XALKORI is an oral monotherapy for patients with anaplastic lymphoma kinase (ALK)-positive advanced or metastatic non-small cell lung cancer (NSCLC).1 XALKORI is Pfizer Canada's first example of personalized medicine for people with ALK-positive non-small cell lung cancer. Lung cancer has been one of the most difficult cancers to treat because symptoms typically do not appear until the disease has already reached an advanced stage.2 Even when symptoms appear, they are often mistaken for other health problems further delaying patients from receiving the care they may need.3 As a percentage of all cancer deaths, lung cancer kills more Canadians (27%) than breast cancer (7%), colorectal cancer (12%) and prostate cancer (5%).4 Approximately 70 Canadians are diagnosed with lung cancer every day and 55 die of lung cancer every day.5 "Little has changed in the way lung cancer has been treated in the past 40 years6," says Dr. Normand Blais, Hemato-Oncologist at CHUM - Hpital Notre-Dame in Montreal. "Previously lung cancer was considered a single disease. With the discovery … Continue reading

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Stem Cell Therapy for Parkinson’s Patient.flv – Video

Posted: Published on May 30th, 2012

30-05-2012 07:23 write to: Read the original: Stem Cell Therapy for Parkinson's Patient.flv - Video … Continue reading

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Stem Cell Therapy for Parkinson's Patient.flv – Video

Posted: Published on May 30th, 2012

30-05-2012 07:23 write to: Read the original: Stem Cell Therapy for Parkinson's Patient.flv - Video … Continue reading

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Man assaults two officers, suspect found with meth, heroin, marijuana, and prescriptions

Posted: Published on May 30th, 2012

by KREM.com KREM.com Posted on May 30, 2012 at 10:25 AM Updated today at 11:19 AM SPOKANE--Spokane Police arrested a 45-year-old- man on May 21 just after 10pm for eluding and assaulting officers. Police say the man was intoxicated and in possession of drugs. On May 21st Sgt. Kurt Vigesaa attempted to stop a possible DUI suspect at Ash and Grace. Instead of stopping as legally required, the suspect driver accelerated in an attempt to get away. The suspect vehicle ended up going south on Ash. As the vehicle crossed the Maple Street Bridge southbound, Corporal Shane Oien was able to deploy spike strips which effectively disabled the vehicle before it entered the downtown area. Sgt Vigesaa was then able to perform a PIT maneuver, stopping the vehicle by the Rosauers parking lot at 1800 W. 2nd. The suspect exited his vehicle, then re-entered and grabbed some items inside, and then ran westbound through the parking lot. Officer Ron Van Tassel arrived on scene and he and Sgt. Vigesaa pursued the running suspect. Just as they caught up to him, the suspect stopped and began swinging at the officers, striking them each on the head. Sgt. Vigesaa and Officer Van … Continue reading

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Drug shows promise of preventing HIV; FDA considers prescriptions for high-risk patients

Posted: Published on May 30th, 2012

WASHINGTON The Associated Press Published Tuesday, May. 08, 2012 1:10PM EDT Last updated Tuesday, May. 08, 2012 1:17PM EDT Federal drug regulators on Tuesday affirmed landmark study results showing that a popular HIV-fighting pill can also help healthy people avoid contracting the virus that causes AIDS in the first place. While the pill appears safe and effective for prevention, scientists stressed that it only works when taken on a daily basis. The Food and Drug Administration will hold a meeting Thursday to discuss whether Truvada should be approved for people who are at risk of contracting HIV through sexual intercourse. The agency's positive review posted Tuesday suggests the daily pill will become the first drug approved to prevent HIV infection in high-risk patients. FDA reviewers conclude that taking Truvada pre-emptively could spare patients infection with a serious and life-threatening illness that requires lifelong treatment. Despite the positive results, reviewers said that patients must be diligent about taking the pill every day. Adherence to the medication was less than perfect in clinical trials, and reviewers said that patients in the real world may forget to take their medication even more than those in clinical studies. First announced in 2010, Truvada's preventive … Continue reading

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New Research Available on the Multi-Billion Dollar Transmucosal Drug Delivery and Systemic Nasal Sprays Markets

Posted: Published on May 30th, 2012

FARMINGTON, Conn., May 30, 2012 /PRNewswire-iReach/ -- Global Information Inc is pleased to announce the immediate availability of two new market research reports from Greystone Research Associates examining the markets for Transmucosal Drug Delivery and Systemic Nasal Sprays. (Photo: http://photos.prnewswire.com/prnh/20120530/CG15754) Oral Transmucosal Drug Delivery MarketGreystone Research Associates' new market study "Oral Transmucosal Drug Delivery: Products, Players, Markets and Forecasts" is a comprehensive evaluation and analysis of the technology, products and participants providing the driving force behind this evolving segment of the healthcare sector. The report offers a detailed understanding of the products, markets and commercial opportunities for drug delivery films, sprays, lozenges, wafers and orally dissolvable tablets that are designed to be administered into the oral cavity and be absorbed systematically via the oral mucosa. The permeability of mucous membranes provides a convenient route for the systemic delivery of new and existing therapeutic drugs. Transmucosal delivery offers the potential for once daily dosing of oral drugs and avoids the effects of first pass metabolism. On the provider side, the development of alternative methods of drug administration has improved the ability of physicians to manage specific problems. Practitioners now recognize the rapid onset, relative reliability, and the general lack of patient … Continue reading

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Marijuana Compound Treats Schizophrenia with Few Side Effects: Clinical Trial

Posted: Published on May 30th, 2012

Gordon Wiltsie / Getty Images A compound found in marijuana can treat schizophrenia as effectively as antipsychotic medications, with far fewer side effects, according to a preliminary clinical trial. Researchers led by Markus Leweke of the University of Cologne in Germany studied 39 people with schizophrenia who were hospitalized for a psychotic episode. Nineteen patients were treated with amisulpride, an antipsychotic medication that is not approved in the U.S., but is comparable to other medications that are. The rest of the patients were given cannabidiol (CBD), a substance found in marijuana that is thought to be responsible for some of its mellowing or anxiety-reducing effects. Unlike the main ingredient in marijuana, THC, which can produce psychotic reactions and may worsen schizophrenia, CBD has antipsychotic effects, according to previous research in both animals and humans. Neither the patients nor the scientists knew who was getting which drug. At the end of the four-week trial, both groups showed significant clinical improvement in their schizophrenic symptoms, and there was no difference between those getting CBD or amisulpride. (MORE: The Complex Link Between Marijuana and Schizophrenia) The results were amazing, says Daniel Piomelli, professor of pharmacology at the University of California-Irvine and a co-author … Continue reading

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Nuvaring Pulmonary Embolism and Deep Vein Thrombosis Risks

Posted: Published on May 30th, 2012

Posted by Shezad Malik MD JDMay 30, 2012 1:09 PM According to medical experts, NuvaRing (etonogestrel/ethinyl estradiol vaginal ring) users are prone to serious and life-threatening NuvaRing blood clots, known as venous thromboembolism, and other dangerous NuvaRing side effects. Recently medical studies, by the U.S. Food & Drug Administration (FDA) and the British Medical Journal, have found that NuvaRing raises the risk of deadly blood clots. The studies demonstrated that NuvaRing increased deep vein thrombosis and pulmonary embolism, when compared to older hormonal birth control pills. NuvaRing side effects include: Deep vein thrombosis Pulmonary embolism Heart attacks Strokes Wrongful death What is NuvaRing? NuvaRing is a hormonal contraceptive device that releases a combination of etonogestrel, a synthetic third generation progestin, and the estrogen, ethinyl estradiol. Merck & Co.s Organon subsidiary, released NuvaRing in 2001. NuvaRing is a small flexible ring that is designed to be inserted into the vagina once a month. NuvaRing prevents pregnancy by releasing controlled amounts of those hormones into the bloodstream. FDA October 2011 Study Continued here: Nuvaring Pulmonary Embolism and Deep Vein Thrombosis Risks … Continue reading

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The Pharmaceutical Market: Russia

Posted: Published on May 30th, 2012

NEW YORK, May 30, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: The Pharmaceutical Market: Russia http://www.reportlinker.com/p0203082/The-Pharmaceutical-Market-Russia.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Pharmaceutical Espicom's highly regarded world pharmaceutical market reports have been redesigned to provide enhanced strategic intelligence in a user-friendly format. Each report provides in-depth information, setting the pharmaceutical market in context. The reports provide: Five-year projections for economic, demographic, health expenditure, health workforce and pharmaceutical market indicators. Specialised intelligence on OTCs, generics, biologics and biosimilars. Exclusive economic and demographic data from the Economist Intelligence Unit (EIU) for each market in the series. A separate statistical health file, comprising health expenditure, health infrastructure, health services and health personnel. The reports are updated quarterly, providing you with the latest information for a full year. In addition, the service will keep you up to date with market and industry news on a regular basis. TABLE OF CONTENTS Read the original: The Pharmaceutical Market: Russia … Continue reading

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