Boosting the production of certain cells could help treat liver disease, new research has suggested. Researchers at the Medical Research Council (MRC) Centre for Regenerative Medicine at the University of Edinburgh said they have discovered how to enhance the production of key cells needed to repair damaged liver tissue. The research could help develop treatments for diseases such as cirrhosis or chronic hepatitis. Scientists hope their work could eventually ease the pressure on waiting lists for liver transplants. Researchers said that when the liver is damaged it produces too many bile duct cells and not enough cells called hepatocytes, which the liver needs to repair damaged tissue. They found they could increase the number of hepatocyte cells - which detoxify the liver - by encouraging these cells to be produced instead of bile duct cells. Understanding how liver cells are formed could help to develop drugs to encourage the production of hepatocytes to repair liver tissue. Professor Stuart Forbes, associate director at the MRC, who is a consultant hepatologist and was the academic leader of the study, said: "Liver disease is on the increase in the UK and is one of the top five killers. Increasing numbers of patients are … Continue reading
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