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Study of live human neurons reveals Parkinson's origins

Posted: Published on February 7th, 2012

ScienceDaily (Feb. 7, 2012) — Parkinson's disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease, which afflicts at least 500,000 Americans and for which there is no cure. The results are published in the current issue of Nature Communications. The UB findings reveal potential new drug targets for the disease as well as a screening platform for discovering new treatments that might mimic the protective functions of parkin. UB has applied for patent protection on the screening platform. "This is the first time that human dopamine neurons have ever been generated from Parkinson's disease patients with parkin mutations," says Jian Feng, PhD, professor of physiology and biophysics in the UB School of Medicine and Biomedical Sciences and the study's lead author. As the first study of human neurons affected by parkin, the UB research overcomes a major roadblock in research on Parkinson's disease and on neurological diseases in general. The problem has been that human neurons live in a complex network in the brain and thus are off-limits to invasive studies, Feng explains. "Before this, we didn't even think about being able to study the disease in human neurons," he says. … Continue reading

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US Navy League HBOT video – Video

Posted: Published on February 7th, 2012

10-12-2011 18:35 A video produced by the US Navy League for the HBOT Volunteer Coalition. The video shows the impact of concussions on our military forces as well as the general population and shows the positive results from hyperbaric oxygen treatment for traumatic brain injuries. Read this article: US Navy League HBOT video - Video … Continue reading

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Through the net video 1_0001.wmv – Video

Posted: Published on February 7th, 2012

09-01-2012 20:32 Every single day someone attends an Emergency Room after a blow or knock to the head. Many of them walk away without receiving any treatment, a diagnosis, or any offer of follow-up care. People are left to cope with these traumatic injuries on their own or are put into the care of their families without being given any information about what to expect. When traumatic brain injury is unsupported - it can easily wreck lives. This has to stop. We want to bring about awareness to bring about change so that what has happened to us, stops happening to thousands of others... Read this article: Through the net video 1_0001.wmv - Video … Continue reading

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WhenSeanSpeaks, Inc. – Video

Posted: Published on February 7th, 2012

20-01-2012 07:28 WhenSeanSpeaks. Inc, was founded to share our message for Injury Prevention and Alcohol Awareness, but more importantly to fund Research for Traumatic Brain Injury Treatment. Our goal is to raise $500000 to be shared between the Schools of Physical Therapy at UT Southwestern, Dallas and UT Medical Branch Galveston. Our vision is to have them focus on the benefits of Exercise in improving the Physical and Cognitive Health and Abilities of Survivors of TBI. Read the original: WhenSeanSpeaks, Inc. - Video … Continue reading

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MS Therapy Centre (NW) – Video

Posted: Published on February 7th, 2012

28-05-2011 11:30 Multiple Sclerosis Therapy Centre (NW) is a self help group and registered charity helping those with MS obtain a better quality of life. Based in Manchester we support people from all over the North West.We receive no statutory funding and rely on public donations to continue our work.Please visit our web site at http://www.tmstc.org More here: MS Therapy Centre (NW) - Video … Continue reading

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My 6 day hospital experience – Diagnostic testing and treatment – Part 9B – Video

Posted: Published on February 7th, 2012

12-09-2011 07:02 A narrative of my 6 day hospital stay in January 2011 for both treatment of a suspected relapse and diagnostic testing for MS... ... (more info) (less info) More: My 6 day hospital experience - Diagnostic testing and treatment - Part 9B - Video … Continue reading

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Dr. Joseph Z Yousefian DMD, MS, PS – Video

Posted: Published on February 7th, 2012

09-12-2011 11:55 http://www.dryousefian.com Dr. Joseph Yousefian is a board-certified orthodontic specialist who has been providing exceptional orthodontic treatment for children and adults in the northwest community since 1991. Specializing in Orthodontistry, TMJ, Sleep Apnea, Invisalign, Stainless Steel Braces, Ceramic Braces, Lingual Braces, Jaw Pain, Sleep Clinic and much more. Dr. Yousefian and his entire staff are dedicated to providing each patient with holistic, state-of-the-art, contemporary orthodontic treatment and courteous personal attention. For more information on treatment for Sleep Apnea and TMJ please contact our office. Our office is designed for your comfort, and our trained, professional staff works as a team to make your visit pleasant. Contrary to cosmetically-oriented orthodontic offices, we maintain a small staff and patient schedule, which enables us to give you the best individualized care possible. Incomparably, you will be seen and treated by Dr. Yousefian at every appointment. Contact us today Phone: 425-562-2921 Email: info@dryousefian.com Website: http://www.dryousefian.com 1515 116th Ave NE Ste 105, Bellevue WA 98004 Read the original here: Dr. Joseph Z Yousefian DMD, MS, PS - Video … Continue reading

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Pluristem to Expand Research & Development of Radiation Exposure Treatment

Posted: Published on February 7th, 2012

HAIFA, Israel, Feb. 7, 2012 (GLOBE NEWSWIRE) -- Pluristem Therapeutics, Inc. (Nasdaq:PSTI - News) (TASE:PLTR) today announced that following preliminary discussions with several governmental authorities, it will expand its research and development efforts on an acute radiation exposure treatment. The announcement comes as governments around the world have broadened their search for easily administered and effective radiation countermeasures. Liat Flaishon, MD, PhD, recently appointed Pluristem's Director of Business Development, will lead the company's development efforts. Dr. Flaishon joins Pluristem after serving as the director of Drug Safety Risk Management in the global drug safety and pharmacovigilance department at Teva Pharmaceuticals. Dr. Flaishon received her medical degree from the Sackler School of Medicine, Tel-Aviv University, and her PhD in Immunology from The Weizmann Institute of Science. As previously announced, Pluristem's PLX cells have achieved favorable pre-clinical data in the treatment of radiation exposure. In studies conducted by Professor Raphael Gorodetsky and his team at the Biotechnology and Radiobiology Laboratory at the Sharett Institute of Oncology at Hadassah Medical Center in Jerusalem, Pluristem's placental 3D expanded cells have demonstrated efficacy as mitigators of the acute radiation syndrome (ARS) following radiation exposure in animals that were given lethal doses of radiation and 24 … Continue reading

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Intellect Neurosciences Files New Patent Applications for Immunotherapy Methods to Target Abnormal Tau Protein in …

Posted: Published on February 7th, 2012

NEW YORK, Feb. 7, 2012 /PRNewswire/ -- Intellect Neurosciences, Inc. (OTCBB:ILNS.PK - News), a biopharmaceutical company engaged in the discovery and development of disease-modifying therapeutic agents for the treatment of Alzheimer's and other neurological diseases today announced it has filed two United States and one international patent application regarding passive and active immunotherapy approaches targeting abnormal forms of tau protein that lead to death of nerve cells in Alzheimer's disease. (Logo: http://photos.prnewswire.com/prnh/20111214/NY22484LOGO) Intellect's new approach specifically targets neoepitopes that are formed following cleavage of intact tau protein by "executioner" caspases. This pathological process is stimulated by an accumulation of amyloid beta in the brain of Alzheimer's patients.  It is believed that the smaller cleaved tau, sometimes referred to as delta tau, is especially toxic and prone to form tangles inside nerve cells. Importantly, Intellect's approach uses antibodies to clear this more toxic form, without risk of interfering with the functions of normal intact tau protein.    "These new patent filings continue to demonstrate our leadership in translational Alzheimer's research and ongoing commitment to develop improved next-generation drug products," said Dr. Daniel G. Chain, Intellect's chairman & CEO.   "We are encouraged by the results of two recent studies conducted by independent groups … Continue reading

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Foundation for Mitochondrial Medicine Awards Grant to Netherlands Research

Posted: Published on February 7th, 2012

ATLANTA, Feb. 7, 2012 (GLOBE NEWSWIRE) -- The Foundation for Mitochondrial Research, a US-based non-profit dedicated to funding research for the treatment of mitochondrial disease, has awarded a $50,000 grant to Professor Jan Smeitink of the Netherlands for his research involving the development of new small molecule compounds to treat mitochondrial dysfunction. The aim of Smeitink's three-year research project is to develop a novel therapy for the treatment of mitochondrial diseases, specifically targeting Leigh's disease, MELAS, LHON and Friedrich ataxia. Research shows that mitochondrial dysfunction is a central element in Autism, Parkinson's, Alzheimer's, muscular dystrophy and Lou Gehrig's disease among others. The funding by the Foundation for Mitochondrial Medicine will enable Smeitink and his research partners to use their specific and complementary expertise in developing new effective compounds to treat mitochondrial diseases. Recently, Khondrion, an offshoot company of the Radboud University Nijmegen Medical Centre (RUNMC) in The Netherlands, has identified several unique drug targets using its cell-based mitochondrial disease model developed in the past few years. In preliminary experiments, Smeitink and his research team provided proof that intervention aimed at these targets can restore or prevent the negative consequences of mitochondrial dysfunction at a cellular level. In this current research … Continue reading

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