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Scientists Transform Skin Cells Direct To Brain Cells, Bypassing Stem Cell Stage

Posted: Published on January 31st, 2012

Featured Article Academic Journal Main Category: Stem Cell Research Also Included In: Neurology / Neuroscience;  Biology / Biochemistry Article Date: 31 Jan 2012 - 2:00 PST email to a friend   printer friendly   opinions   Current Article Ratings: Patient / Public: 5 (1 votes) Healthcare Prof: Bypassing the stem cell stage, researchers at the Stanford University School of Medicine in California converted mouse skin cells directly into neural precursor cells, the cells that go on to form the three main types of cell in the brain and nervous system. They write about their findings in the 30 January early online issue of the Proceedings of the National Academy of Sciences. The findings of this and an earlier study question the idea that pluripotency (the ability to become virtually any other cell in the body, a key characteristic of stem cells) is a necessary stage in the conversion of one cell type to another. In the earlier study, the same team transformed mouse and human skin cells directly into functional neurons. But this study is a substantial advance on the earlier one for two reasons. First, neural precursor cells can not only differentiate into neurons, they can also become either of … Continue reading

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Scientists Transform Skin Cells Direct To Brain Cells, Bypassing Stem Cell Stage

Posted: Published on January 31st, 2012

Featured Article Academic Journal Main Category: Stem Cell Research Also Included In: Neurology / Neuroscience;  Biology / Biochemistry Article Date: 31 Jan 2012 - 2:00 PST email to a friend   printer friendly   opinions   Current Article Ratings: Patient / Public: 5 (1 votes) Healthcare Prof: Bypassing the stem cell stage, researchers at the Stanford University School of Medicine in California converted mouse skin cells directly into neural precursor cells, the cells that go on to form the three main types of cell in the brain and nervous system. They write about their findings in the 30 January early online issue of the Proceedings of the National Academy of Sciences. The findings of this and an earlier study question the idea that pluripotency (the ability to become virtually any other cell in the body, a key characteristic of stem cells) is a necessary stage in the conversion of one cell type to another. In the earlier study, the same team transformed mouse and human skin cells directly into functional neurons. But this study is a substantial advance on the earlier one for two reasons. First, neural precursor cells can not only differentiate into neurons, they can also become either of … Continue reading

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Scientists Transform Skin Cells Direct To Brain Cells, Bypassing Stem Cell Stage

Posted: Published on January 31st, 2012

Featured Article Academic Journal Main Category: Stem Cell Research Also Included In: Neurology / Neuroscience;  Biology / Biochemistry Article Date: 31 Jan 2012 - 2:00 PST email to a friend   printer friendly   opinions   Current Article Ratings: Patient / Public: 5 (1 votes) Healthcare Prof: Bypassing the stem cell stage, researchers at the Stanford University School of Medicine in California converted mouse skin cells directly into neural precursor cells, the cells that go on to form the three main types of cell in the brain and nervous system. They write about their findings in the 30 January early online issue of the Proceedings of the National Academy of Sciences. The findings of this and an earlier study question the idea that pluripotency (the ability to become virtually any other cell in the body, a key characteristic of stem cells) is a necessary stage in the conversion of one cell type to another. In the earlier study, the same team transformed mouse and human skin cells directly into functional neurons. But this study is a substantial advance on the earlier one for two reasons. First, neural precursor cells can not only differentiate into neurons, they can also become either of … Continue reading

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BrainStorm Cell Therapeutics (OTCBB:BCLI) Has Potentially Developed A Treatment For ALS

Posted: Published on January 31st, 2012

Newswise — In the quest to find treatments for certain neurological diseases, BrainStorm is fast distinguishing itself as a leader in the field of regenerative medicine using stem cells through its unique platform called NurOwn. The Company can process human mesenchymal stem cells, which are present in bone marrow and are capable of self-renewal as well as differentiation into many other tissues. What makes BrainStorm technology platform very attractive to Big Pharma partnering is the autologous nature of the bone marrow-derived stem cells. This will in turn drastically reduce the expected translation time to market. The value of a treatment for ALS in the U.S. and EU is estimated to be $4Billion. The potential applications for the NurOwn platform to treat disease is fast becoming a reality. In short, BrainStorm is leveraging a patients own cells to heal itself of disease. BrainStorm updated stakeholders recently with a review of the trial six months post transplantation. The Phase I/II clinical trial for ALS is being conducted at the prestigious Hadassah Medical Center in Jerusalem by renowned Professor Dimitrios Karussis, M.D., Ph.D. and a distinguished scientific team in its own right from BrainStorm headed by Professor Eldad Melamed. Patients have been transplanted … Continue reading

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StemCells, Inc. Announces Publication of Preclinical Data Demonstrating Its Human Neural Stem Cells Preserve Vision

Posted: Published on January 31st, 2012

NEWARK, Calif., Jan. 30, 2012 (GLOBE NEWSWIRE) -- StemCells, Inc. (Nasdaq:STEM - News) today announced the publication of preclinical data demonstrating that its proprietary HuCNS-SC(R) cells (purified human neural stem cells) protect host photoreceptors and preserve vision in an animal model of retinal disease. The preclinical results are highly relevant to human disorders of vision loss, the most notable of which is dry age-related macular degeneration (AMD). The study is available online at http://onlinelibrary.wiley.com/doi/10.1111/j.1460-9568.2011.07970.x/abstract and will be featured as the cover article in the February issue of the international peer-reviewed European Journal of Neuroscience. This research was conducted in collaboration with a team of researchers led by Raymond Lund, Ph.D., Professor Emeritus of Ophthalmology, and Trevor McGill, Ph.D., Research Assistant Professor at the Casey Eye Institute, Oregon Health and Science University. The results of the study show that photoreceptors, the key cells of the eye involved in vision, were protected from degeneration following transplantation of HuCNS-SC cells into the Royal College of Surgeons (RCS) rat. The RCS rat is a well-established model of retinal disease which has been used extensively to evaluate potential cell therapies. Moreover, the number of cone photoreceptors, which are responsible for central vision, remained constant over … Continue reading

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Stage-4 breast cancer survivor talks about stem cell treatment – Video

Posted: Published on January 31st, 2012

25-01-2012 18:06 A former stage-IV breast cancer patient talks about being treated at Stanford over a dozen years ago as part of a small clinical trial testing whether high-dose chemotherapy, followed by blood stem cell rescue with purified hematopoietic stem cells, could cure her cancer. Read more: Stage-4 breast cancer survivor talks about stem cell treatment - Video … Continue reading

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Gingrich Vows to Ban Embryonic Stem Cell Research

Posted: Published on January 31st, 2012

(Photo: REUTERS/Shannon Stapleton) U.S. Republican presidential candidate and former Speaker of the House Newt Gingrich (R) speaks to the media after attending a church service at the Exciting Idlewild Baptist Church in Lutz, Florida January 29, 2012. "I believe life begins at conception," the Republican presidential hopeful stressed Sunday at a news conference outside a Baptist church in Lutz, Fla. "The question I was raising was what happens to embryos in fertility clinics," Gingrich added, referring to the remarks he made a day earlier at another Baptist church in Winter Park, that embryonic stem-cell research amounts to "the use of science to desensitize society over the killing of babies." Gingrich's proposal was seen as an attempt to woo evangelical voters and gain an edge over former Mass. Gov. Mitt Romney, his biggest opponent in Florida. Gingrich went on to say he was in favor of a commission to "look seriously" at the ethics of how fertility clinics are managed. "If you have in vitro fertilization, you are creating life; therefore, we should look seriously at what the rules should be for clinics that are doing that, because they are creating life," The Associated Press quoted him as saying outside Exciting … Continue reading

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Giulio’s strategy is to cure dystrophy with stem cell treatment – Video

Posted: Published on January 31st, 2012

20-01-2012 04:21 http://www.telethon.it - A Telethon researcher for many years, Giulio Cossu is the director of the Regenerative Medicine Unit at the San Raffaele Institute in Milan and a professor of Histology at Milan University. After training to become a doctor, he then chose research, also spending many years abroad. He has always studied muscular dystrophies and is preparing treatment for Duchenne muscular dystrophy based on the use of certain stem cells present in the blood called mesoangioblasts. The first clinical trials on human beings for this innovative stem cell treatment will begin in 2011. Giulio Cossu's project entitled "Mesoangioblast transplantation for Duchenne muscular dystrophy: stage I clinical trials" is funded by Telethon-UILDM. Originally posted here: Giulio's strategy is to cure dystrophy with stem cell treatment - Video … Continue reading

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Cerebral Palsy Treatment by Dr.Babu Sudheendra Nath – Video

Posted: Published on January 31st, 2012

21-01-2011 00:27 World' First Successful Treatment for Cerebral Palsy Centre in Thrissur. Sree Chithra Panchakarma Research Centre and Speciality Ayurveda Hospital, 1st Avenue, Civil Lane, Po. Ayyanthole, Thrissur - 680003, Kerala. Website: http://www.sreechithra.com Phone: 0091 487 2384055, 9387111124, 9400737270. Email ; drbabunath@gmail.com Original post: Cerebral Palsy Treatment by Dr.Babu Sudheendra Nath - Video … Continue reading

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Study aims to aid troops with mild brain injury

Posted: Published on January 31st, 2012

A team of experts at San Antonio Military Medical Center has launched a military study aimed at improving outcomes for service members suffering from a signature wound of today's wars: traumatic brain injury (TBI). The Study of Cognitive Rehabilitation Effectiveness, dubbed the SCORE trial, is examining cognitive rehabilitation therapy's value as a treatment for service members with mild TBI. The Defense and Veterans Affairs departments teamed up on this study to determine the best treatment for combat troops who are experiencing mild TBI symptoms — such as difficulties with attention, concentration, memory and judgment — three to 24 months post-injury, explained Douglas B. Cooper, the study's lead and a clinical neuropsychologist for the center's Traumatic Brain Injury Service. “We have a lot of great interventions to help … in the first few days after concussion,” he said. However, “we don't have as many good interventions later on — six months, 12 months or two years post-injury,” added Cooper, who also serves as the director of the Military Brain Injury Rehabilitation Research Consortium. The trial's aim is to determine if cognitive rehabilitation therapy improves chronic mild TBI symptoms and, if so, which interventions work best, on whom and why. Cognitive rehabilitation, … Continue reading

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