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How does IVF work, how much does the fertility treatment cost and what is the success rate for in vitro fertilisation? – The Sun

Posted: Published on September 8th, 2017

baby boom The process can use eggs and sperm from the couple themselves, or these can be sourced from a donor ONE of the techniques used to help women with fertility problems who are struggling to have a baby is in vitro fertilisation (IVF). But what does process involve and who qualifies for the treatment on the NHS? Getty - Contributor The process involves removing an egg from a womans ovaries and fertilising them using sperm in a laboratory. The fertilised egg, also known as an embryo, is transferred back into a womans womb to grow. The process can use eggs and sperm from the couple themselves, or these can be sourced from a donor. There are six main stages of IVF: Getty - Contributor The National Institute for Health and Care Excellence (NICE)recommends in its fertility guidelines that IVF should be offered to: Those who have been recommended by NICE for NHS-funded IVF in England will then have to be approved by localClinical Commissioning Groups (CCGs) who can have stricter criteria. These requirements can include: If a woman doesnt qualify for IVF on the NHS, treatment is available at a private clinic. Getty - Contributor Costs can vary depending … Continue reading

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Stormont deadlock blamed for fertility treatment delays – BBC News

Posted: Published on September 8th, 2017

Image caption Della McGill and Ryan Cunningham say IVF offers them an opportunity to have a baby A County Down couple have said the political deadlock at Stormont is delaying their chance of becoming parents. Della McGill has suffered two ectopic pregnancies and said in vitro fertilisation offered her and and Ryan Cunningham the chance of having a baby. Last month, the Belfast Health Trust announced a temporary halt on offering fertility treatment as part of a raft of cost-cutting proposals. Access to the Regional Fertility Centre for an estimated 320 new patients would be deferred until next April, it said. They would then join a waiting list that is already up to nine months long for certain treatments. Ms McGill, 35, said she was "heartbroken" when she heard the news. "The current political deadlock at Stormont has obviously contributed to all the other problems that we are facing, the uncertainty of our future and the possible postponement of potentially never having our family and we aren't getting any younger," she told BBC news NI. "We've already been through a nightmare for two years. I have suffered two ectopic pregnancies and lost one fallopian tube. "Our hearts are broken." The … Continue reading

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Free IVF on the NHS scrapped in Cambridgeshire – Cambridge News – Cambridge News

Posted: Published on September 8th, 2017

Free IVF treatment on the NHS in Cambridgeshire has been scrapped - despite 82 per cent of survey respondents disagreeing with the move and thousands signing a petition opposing it. Instead of getting the first cycle of IVF free through the NHS, hopeful parents will have to pay for each cycle, according to the Cambridgeshire and Peterborough Clinical Commissioning Group (CCG). The CCG decided to cut funding for specialist fertility treatment to save 700,000, helping ease its current financial concerns. Cambridgeshire is now one of only five regions not to offer any NHS-funded speciality fertility treatment. Infertility, which is categorised as a disease by the World Health Organisation, affects one in six people. Berenice Smith, who underwent six unsuccessful IVF treatments, said it was incredibly disappointing that affordable fertility treatment came down to a 'postcode lottery'. She said: "It is incredibly sad, incredibly sad that people [who want to conceive] have to make these appalling choices." A previous online survey found that 82 per cent of people did not agree with the plans to cut funding. A 2,278 signature petition opposing the proposals was also submitted by Stuart Tuckwood, a representative of UNISON Acute Hospitals. Ms Smith said the overwhelming … Continue reading

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IVF treatment set to be cut despite overwhelming opposition from Peterborough and Cambridgeshire residents – Peterborough Telegraph

Posted: Published on September 8th, 2017

IVF treatment in Peterborough and the rest of Cambridgeshire is set to be cut despite overwhelming opposition to the plans. The specialist fertility service is to be removed by the Cambridgeshire and Peterborough Clinical Commissioning Group (CCG), barring two exceptions, until at least April 2019 despite more than 80 per cent of respondents to a public consultation opposing the cost-cutting measure. In total, nearly 797 people formally opposed the plans, while a petition of 2,278 was also handed in. Moreover, none of the organisations which took part in the consultation supported the measure, with many suggesting that the CCG continue to fund one round of IVF. However, the CCG's governing body is set to press ahead with its decision to cut all IVF treatment except for patients with cancer or another disease which is likely to make them infertile, or if they have a chronic viral infection. Papers released ahead of its meeting at the Future Business Centre at the ABAX Stadium in Peterborough on Tuesday (September 5) recommend that the governing body cut IVF but review the decision in 2019. The move will save the body, which commissions health services in the county, 700,000 a year as it bids … Continue reading

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Best Hair Treatment | Ovation Hair Cell Protein Therapy

Posted: Published on September 8th, 2017

Recommended For You Cell Therapy Hair Treatment 12oz $56.95 New worth 9 loyalty points All Hair Types The unique micro-technology of the complex proteins in Cell Therapy penetrate the hair cortex, building strand strength from within. Use 2-3 times per week. Prepare hair by washing with an Ovation Hair Shampoo. Place a quarter to half dollar size amount (depending on hair length) of Ovation Cell Therapy in your palm. Massage into scalp and comb through to ends. Leave on for 3-5 minutes and rinse thoroughly. Follow with an Ovation Conditioner or Crme Rinse. Towel dry and style as desired. Testimonials What our customers are saying... I have noticed a tremendous difference in my hair. It is getting longer, and feels much thicker and looks healthier. I am amazed and love it. My sister uses it and raved about it, and ended up getting me a set of it for my birthday a year ago. I have been using it ever since. Lisa A. Ovation Hair Cell Therapy has worked miracles with my hair! It has significantly improved its texture and strength and reduced the amount lost with shampooing! Stephanie M. Very happy with Ovation Cell Therapy! Noticeabley healthier hair after … Continue reading

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Cell therapy emergence opens up new markets for shippers, logistic companies – BioPharma Dive

Posted: Published on September 8th, 2017

Dive Brief: CAR-T therapy has already pushed the boundaries of what's possible in treating patients with certain types of aggressive blood cancers that are resistant to other treatments. The remarkable clinical efficacy seen in these patients, who would otherwise have few remaining options, stoked optimism that reprogramming T-cells to target and destroy cancers could transform the standard of care. That promise has led to heavy investment from biotech and pharma companies eager to become leaders in the still-emerging cell therapy space. Such investment has, in turn, created new market opportunities for companies that specialize in managing complex logistics and shipping networks. Cryoport, for example, has inked deals with both Novartis, Kite Pharma Inc. and several other cell therapy companies to help with cryopreservation of patient T-cells and what's known as chain-of-identity monitoring. Since most CAR-T therapies currently in development are made directly from a patient's own cells, companies need to ensure that reprogrammed cells are correctly matched and returned to the original patient. That requires the ability to identify a shipment of patient cells along every step of transport, from hospital through manufacturing and back to the same hospital again. Challenges like these add new risks and hurdles to the … Continue reading

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GSK Exercises Option over SPEAR T-cell Therapy Program Targeting NY-ESO – Drug Discovery & Development

Posted: Published on September 8th, 2017

Adaptimmune Therapeutics, a leader in T-cell therapy to treat cancer, announced thatGlaxoSmithKline plc(LSE:GSK) (NYSE:GSK) has exercised its option under a collaboration and license agreement signed in 2014 to exclusively license the right to research, develop, and commercialize Adaptimmunes NY-ESO SPEAR T-cell therapy program. Further details will be provided in a conference call scheduled for8:30 AM EDTthis morning; dial-in and webcast details are provided below. Adaptimmune will receive up to 48 million (~$61 million) from GSK over the course of the transition period. This includes development milestones of up to 18 million (~$23 million) and the option payment of 30 million (~$38 million), which also allows GSK to nominate two additional targets following completion of the transition. Successful continuation of development and subsequent commercialization of NY-ESO would trigger additional payments for development milestones, tiered sales milestones, and mid-single to low double-digit royalties on worldwide net sales. This is a very exciting day for Adaptimmune as GSK has exercised its option over our NY-ESO program, earlier than originally planned, commentedJames Noble, Chief Executive Officer at Adaptimmune. The commitment by one of the worlds leading pharmaceutical companies to the NY-ESO SPEAR T-cell program as a new treatment modality is a testament to the … Continue reading

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Cellectis shares slump as death puts cell therapy tests on hold – Reuters

Posted: Published on September 8th, 2017

LONDON (Reuters) - French cell therapy specialist Cellectis, which is developing a gene-modified cancer treatment similar to Novartiss recently approved Kymriah, has been forced to suspend testing following a patient death. Cellectis said on Tuesday it was working closely with the U.S. Food and Drug Administration in order to resume trials with a lower dose of the medicine UCART123. Shares in the company fell 26 percent in morning trade following the U.S. regulators decision to place a so-called clinical hold on two early-stage trials of the medicine in blood cancers. Novartis made history last week when it won approval for its $475,000 drug Kymriah, the first in a new class of treatments called CAR-T immunotherapies that use modified disease-fighting T cells to attack cancer. While Novartis and rivals such as Juno and Kite use cells from the patients own body, Cellectiss gene edited cell therapy product offers an off-the-shelf, or allogeneic, option by deriving cells from healthy donors. It is designed to help patients with acute myeloid leukemia (AML) and blastic plasmacytoid dendritic cell neoplasm (BPDCN). However, the first patient treated in the BPDCN study, a 78-year-old man, died after experiencing cytokine release syndrome (CRS), a dangerous release of cell-signaling … Continue reading

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Stem Cell Therapy: A Lethal Cure – Medical News Bulletin

Posted: Published on September 8th, 2017

Stem cell therapy is a two-step process. First, the patients blood cells are destroyed by chemotherapy, radiation therapy or immunosuppression. This conditioning process also eradicates any cancer cells that survived first-line treatment. Second, the patient receives stem cells harvested from a donors bone marrow or peripheral blood (circulating blood). While this can be an effective cure, it can cause graft-versus-host disease (GVHD) in up to 50% of patients. GVHD is more likely to develop in patients who have received a peripheral blood transplant and can kill 15%-20% of patients. Two types of GVHD can develop, acute and chronic, and patients may develop either one, both or neither type. GVHD is less likely to occur and symptoms are milder if the donor cells closely match those of the patient. Acute GVHD can develop within 100 days of a transplant. The first step of stem cell therapy can cause tissue damage, and bacteria from the gut can escape into the bloodstream. This primes the patients antigen-presenting cells (cells that activate the immune response), which subsequently encourage donor T cells to proliferate and attack the patients tissues. Symptoms include vomiting, diarrhea, skin rashes, nausea, vomiting and liver problems. This can be resolved relatively … Continue reading

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GE launches cell therapy thawing tech – BioPharma-Reporter.com – BioPharma-Reporter.com

Posted: Published on September 8th, 2017

GE Healthcare has launched a thawing technology for cell therapies it says removes the risks and inconsistencies of standard water baths. Water bath thawing is the most common method for thawing cell therapies, Philip Vanek, GEs general manager of Cell Therapy Growth Strategy told Biopharma-Reporter. However, potential inconsistencies arise due to subjective determination of the thaw endpoint and risk of water-borne contamination, at the very point where the product is most valuable and most vulnerable. There is no easy way to record what is happening to a sample which makes it hard to know if procedures are all being followed identically, he continued, adding the process is labour-intensive, requiring staff to regularly complete contamination control procedures. Therefore the firm has launched the VIA Thaw CB1000, an automated platform for the dry thawing of cryo-bags which Vanek told us overcomes these problems. VIA Thaw constantly monitors the sample temperature across multiple locations, records everything that happens in a comprehensive log and even takes a photo of the thawed therapy to prove it has been correctly handled. Furthermore, the system requires no specialist skills to operate and delivers high recoveries of viable cells. Blossoming space The personalised medicine space is just beginning … Continue reading

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