Page 4,934«..1020..4,9334,9344,9354,936..4,9404,950..»

14th Carnegie Center 5K and Fun Run to Raise Funds and Awareness for Parkinson's Research Will be Held on September …

Posted: Published on September 4th, 2013

Home Mail News Sports Finance Weather Games Groups Answers Flickr More omg! Shine Movies Music TV Health Shopping Travel Autos Homes Mobile Yahoo! News Search News Search Web Sign In Mail Help Account Info Help Suggestions Yahoo! Home Video Photos GMA Year in Review Odd Comics Travel Opinion Trending Now Who Knew? Weather The Upbeat U.S. U.S. Video GMA Education Religion Crimes and Trials Local Contributor Network Year In Review World World Video Middle East Europe Latin America Africa Asia Canada Australia/Antarctica Business Video Exclusives Today's Markets Stocks Personal Finance Marketplace Entertainment Video Clinton Concert Celebrity TV Movies Music Fashion Books Arts Theater Dear Abby Comics Odd News Sports Video NFL MLB NBA NCAAF NCAAB Soccer Cycling NHL Tennis Golf Boxing Motor Sports MMA Olympics Tech Gadgets Wireless Apple Social Media Security Open Source Gaming Apps This Could Be Big Upgrade Your Life Politics Remake America The Issues Women and Politics Press Releases Video Science Science Video Weather News Space / Astronomy Pets Dinosaurs / Fossils Biotech Energy Green Health Video Weight Loss Cancer Sexual Health Medications/Drugs Parenting/Kids Seniors/Aging Diseases/Conditions Blogs The Sideshow Katie's Take Power Players This Could Be Big Newsmakers Trending Now The Upbeat Who Knew? Nightline Fix … Continue reading →

Posted in Parkinson's Treatment | Comments Off on 14th Carnegie Center 5K and Fun Run to Raise Funds and Awareness for Parkinson's Research Will be Held on September …

Chronic treatment with Addex Dipraglurant Rescues Impairment of Long-Term Synaptic Plasticity in a Validated …

Posted: Published on September 4th, 2013

Geneva, Switzerland, 4 September 2013 - Addex Therapeutics (ADXN.SW), a leading company pioneering allosteric modulation-based drug discovery and development announced today additional positive preclinical data for its mGlu5 negative allosteric modulator (NAM) oral small molecule, dipraglurant, in a validated model for primary generalized torsion dystonia 1 (DYT1), a common and severe genetic form of dystonia, caused by a mutation in the TOR1A gene encoding the torsin A protein. In the study, that is part of an ongoing collaboration with Professor Antonio Pisani, University of Rome Tor Vergata and Fondazione Santa Lucia, chronic treatment with dipraglurant (50 mg/kg i.p. for 8 days) partially restored long-term depression and synaptic de-potentiation which are impaired in the DYT1 mutant mice over expressing the human mutant TOR1A gene. These data together with previously reported results obtained with dipraglurant in in vitro and in in vivo preclinical behavioral models, as well as observations made in the Phase 2a study of dipraglurant in Parkinson`s disease patients, further support the hypothesis that inhibition of mGlu5 could be beneficial in counteracting the abnormal electrophysiological function observed in dystonia. In keeping with the Company`s rare disease development strategy, Addex plans to initiate a Phase 2a study with dipraglurant in a … Continue reading →

Posted in Parkinson's Treatment | Comments Off on Chronic treatment with Addex Dipraglurant Rescues Impairment of Long-Term Synaptic Plasticity in a Validated …

Parkinson's Australia disappointed research may not have been carried out by university researchers

Posted: Published on September 4th, 2013

Parkinson's Australia says it is disappointed a study with the potential to help patients may not have actually taken place. The organisation gave the University of Queensland a grant of $20,000 after positive study findings into the treatment were published. on Tuesday saying an internal investigation had revealed a study by a former staff member using a technique called Transcranial Magnetic Stimulation may not have been carried out. Parkinson's Australia's John Bird said the revelations are unfortunate as patients are keen to find a cure and ease the pain and discomfort of the illness. "We are obviously disappointed," Mr Bird said. The grant money has since been returned. Professor Bruce Murdoch, a former staff member from the university's Centre for Neurogenic Communication Disorders Research, was one of the authors of the article. The ABC has learnt other research by Professor Murdoch is now being reviewed. Professor Murdoch retired six weeks ago and his profile has been removed from the university's web site. A spokesman for the Stroke Foundation said it asked the university to look into research done by Professor Murdoch with Stroke Foundation money. Continued here: Parkinson's Australia disappointed research may not have been carried out by university researchers … Continue reading →

Posted in Parkinson's Treatment | Comments Off on Parkinson's Australia disappointed research may not have been carried out by university researchers

Ground breaking research identifies promising drugs for treating Parkinson's

Posted: Published on September 4th, 2013

Public release date: 3-Sep-2013 [ | E-mail | Share ] Contact: Amy Pullan a.l.pullan@sheffield.ac.uk 01-142-229-859 University of Sheffield New drugs which may have the potential to stop faulty brain cells dying and slow down the progression of Parkinson's, have been identified by scientists in a pioneering study which is the first of its kind. Experts from the world leading Sheffield Institute for Translational Neuroscience (SITraN) conducted a large scale drugs trial in the lab using skin cells from people with this progressive neurological condition which affects one in every 500 people in the UK. The researchers tested over 2,000 compounds to find out which ones could make faulty mitochondria work normally again. Mitochondria act as the power generators in all cells of our body, including the brain. Malfunctioning mitochondria are one of the main reasons why brain cells die in Parkinson's. One of the promising medications identified though the research is a synthetic drug called ursodeoxycholic acid (UDCA). This licenced drug has been in clinical use for several decades to treat certain forms of liver disease which means that researchers will be able to immediately start a clinical trial to test its safety and tolerability in people with Parkinson's. This … Continue reading →

Posted in Parkinson's Treatment | Comments Off on Ground breaking research identifies promising drugs for treating Parkinson's

Treatment of children with cerebral palsy could be boosted by Strathclyde research

Posted: Published on September 4th, 2013

Public release date: 4-Sep-2013 [ | E-mail | Share ] Contact: Lachlan Mackinnon lachlan.mackinnon@strath.ac.uk 44-014-154-84123 University of Strathclyde Children with cerebral palsy could be helped to speak more clearly following research by a University of Strathclyde academic. Dr Anja Kuschmann will analyze the speech patterns of young people affected by the condition, in an effort to understand more about why they can have difficulties talking. Cerebral palsy (CP) is usually caused by an injury to the brain before, during or after birth. Children with CP have difficulties in controlling muscles and movements as they grow and develop. Discovering more about how the speech of children with CP is affected by muscular problems and brain damage could, Dr Kuschmann believes, lead to improvements in diagnosis and therapy. She said: "Many children with CP have difficulties with speech melody, rhythm and stress. These difficulties, generally referred to as prosodic difficulties, can affect the intelligibility of a child's speech, and are therefore of great clinical importance. "However, the development of prosody in children with CP is currently not well understood. As a result, it is not certain whether prosodic difficulties in CP are due to muscular problems during speaking or the inability to … Continue reading →

Posted in Cerebral Palsy Treatment | Comments Off on Treatment of children with cerebral palsy could be boosted by Strathclyde research

BHR Pharma Announces SyNAPSe® Trial Completes Patient Enrollment

Posted: Published on September 4th, 2013

HERNDON, Va., Sept. 3, 2013 /PRNewswire/ --BHR Pharma, LLC (BHR) announced today that it has successfully randomized the 1,180th and final patient into its global, Phase III SyNAPSe Trial. The study is evaluating the safety and efficacy of BHR's proprietary intravenous progesterone formulation, BHR-100, for treating severe traumatic brain injury (TBI). If the final data support BHR-100 efficacy, the drug could be the first-ever approved treatment for TBI. The study's last patient was enrolled in the United States at the University of Iowa Hospitals and Clinics. In total, the SyNAPSe trial has 154 participating sites in the United States, Israel, Argentina, and 18 other countries in Europe and Asia. "Achieving our enrollment goal is a significant milestone worth celebrating, especially in light of the many failed TBI trials that have come before and the significant difficulty of enrolling patients within eight hours after the initial injury," said Roland Gerritsen van der Hoop, M.D., Ph.D., BHR Pharma Chief Medical Officer and Head of Global Research and Development. "The study now moves into its important final phase patient follow up and data collection. We will continue to work closely with our sites to ensure that these activities are completed in full." SyNAPSe … Continue reading →

Posted in Brain Injury Treatment | Comments Off on BHR Pharma Announces SyNAPSe® Trial Completes Patient Enrollment

Four ex-NFL players file new concussion lawsuit against league

Posted: Published on September 4th, 2013

NEW ORLEANS -- Four former NFL players have sued the league and its helmet maker, claiming they hid information about the dangers of brain injury. They want medical care for past, current and future NFL players. The ex-players -- Jimmy Williams, Rich Mauti, Jimmy Keyes and Nolan Franz -- filed the federal lawsuit in New Orleans on Sunday. Last week, the NFL tentatively agreed to pay $765 million to past players with health problems that can be caused by concussions, but some said the amount should have been more. James Dugan II, the attorney for the former players bringing the new suit, did not immediately return a call and email seeking comment. Neither the league nor helmet maker Riddell, Inc. would comment Tuesday about the new suit, which claims they failed to protect players from brain injuries. Riddell isn't part of the proposed settlement. The players say they have suffered one or more traumatic brain injuries. They want the NFL and Riddell to set up and pay for a medical monitoring and treatment program for all former, current and future NFL players. Like earlier lawsuits, this one claims the league and Riddell failed to protect players from brain injuries. Three … Continue reading →

Posted in Brain Injury Treatment | Comments Off on Four ex-NFL players file new concussion lawsuit against league

Four ex-NFL players file new suit against league on concussions

Posted: Published on September 4th, 2013

NEW ORLEANS -- Four former NFL players have sued the league and its helmet maker, claiming they hid information about the dangers of brain injury. They want medical care for past, current and future NFL players. The ex-players -- Jimmy Williams, Rich Mauti, Jimmy Keyes and Nolan Franz -- filed the federal lawsuit in New Orleans on Sunday. Last week, the NFL tentatively agreed to pay $765 million to past players with health problems that can be caused by concussions, but some said the amount should have been more. James Dugan II, the attorney for the former players bringing the new suit, did not immediately return a call and email seeking comment. Neither the league nor helmet maker Riddell, Inc. would comment Tuesday about the new suit, which claims they failed to protect players from brain injuries. Riddell isn't part of the proposed settlement. The players say they have suffered one or more traumatic brain injuries. They want the NFL and Riddell to set up and pay for a medical monitoring and treatment program for all former, current and future NFL players. Like earlier lawsuits, this one claims the league and Riddell failed to protect players from brain injuries. Three … Continue reading →

Posted in Brain Injury Treatment | Comments Off on Four ex-NFL players file new suit against league on concussions

4 ex-NFL players file new suit on concussions

Posted: Published on September 4th, 2013

Home Mail News Sports Finance Weather Games Groups Answers Flickr More omg! Shine Movies Music TV Health Shopping Travel Autos Homes Mobile Yahoo! News Search News Search Web Sign In Mail Help Account Info Help Suggestions Yahoo! Home Video Photos GMA Year in Review Odd Comics Travel Opinion Trending Now Who Knew? Weather The Upbeat U.S. U.S. Video GMA Education Religion Crimes and Trials Local Contributor Network Year In Review World World Video Middle East Europe Latin America Africa Asia Canada Australia/Antarctica Business Video Exclusives Today's Markets Stocks Personal Finance Marketplace Entertainment Video Clinton Concert Celebrity TV Movies Music Fashion Books Arts Theater Dear Abby Comics Odd News Sports Video NFL MLB NBA NCAAF NCAAB Soccer Cycling NHL Tennis Golf Boxing Motor Sports MMA Olympics Tech Gadgets Wireless Apple Social Media Security Open Source Gaming Apps This Could Be Big Upgrade Your Life Politics Remake America The Issues Women and Politics Press Releases Video Science Science Video Weather News Space / Astronomy Pets Dinosaurs / Fossils Biotech Energy Green Health Video Weight Loss Cancer Sexual Health Medications/Drugs Parenting/Kids Seniors/Aging Diseases/Conditions Blogs The Sideshow Katie's Take Power Players This Could Be Big Newsmakers Trending Now The Upbeat Who Knew? Nightline Fix … Continue reading →

Posted in Brain Injury Treatment | Comments Off on 4 ex-NFL players file new suit on concussions

Creating a ‘Window to the Brain’

Posted: Published on September 4th, 2013

University of California, Riverside researchers develop novel transparent skull implant that could provide new treatment options for disorders such as brain cancer and traumatic brain injury By Sean Nealon on September 3, 2013 Members of the research team, from left, Javier Garay, Yasuhiro Kodera, Carissa L. Reynolds, Yasaman Damestani, Guillermo Aguilar, Masaru P. Rao and B. Hyle Park. RIVERSIDE, Calif. (www.ucr.edu) A team of University of California, Riverside researchers have developed a novel transparent skull implant that literally provides a window to the brain, which they hope will eventually open new treatment options for patients with life-threatening neurological disorders, such as brain cancer and traumatic brain injury. The teams implant is made of the same ceramic material currently used in hip implants and dental crowns, yttria-stabilized zirconia (YSZ). However, the key difference is that their material has been processed in a unique way to make it transparent. A version of the transparent skull implant developed by UC Riverside researchers. Since YSZ has already proven itself to be well-tolerated by the body in other applications, the teams advancement now allows use of YSZ as a permanent window through which doctors can aim laser-based treatments for the brain, importantly, without having to … Continue reading →

Posted in Brain Injury Treatment | Comments Off on Creating a ‘Window to the Brain’

Page 4,934«..1020..4,9334,9344,9354,936..4,9404,950..»