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Research and Markets: Special Report: Market Opportunities in Symptomatic Treatments of Multiple Sclerosis

Posted: Published on September 17th, 2012

DUBLIN--(BUSINESS WIRE)-- Research and Markets (http://www.researchandmarkets.com/research/qshfb5/special_report) has announced the addition of Decision Resources, Inc's new report "Special Report: Market Opportunities in Symptomatic Treatments of Multiple Sclerosis" to their offering. Current treatment for the symptoms associated with multiple sclerosis (MS) is dominated by generic, off-label therapies with mixed efficacy or modest clinical trial evidence. Acorda Therapeutics' Ampyra, Allergan's Botox, and Avanir Pharmaceuticals' Nuedexta make up the crop of new niche agents in the United States indicated specifically for the treatment of individual symptoms that commonly occur in patients with this chronic disease. Although these agents are available, demand for additional therapies that offer relief of disabling MS-related symptoms remains high, and agents that can demonstrate clinically meaningful efficacy have the potential to command sizable prices and enjoy modest uptake in discrete, and in some cases sizable, patient subgroups in this lucrative market. Key Topics Covered: - Executive Summary - Strategic Considerations - Stakeholder Implications - Introduction - Overview of Multiple Sclerosis - Current Therapies and Patient Estimates for MS-Associated Symptoms View post: Research and Markets: Special Report: Market Opportunities in Symptomatic Treatments of Multiple Sclerosis … Continue reading

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Multiple sclerosis patients, doctors appreciate help from Ann Romney, Michelle Obama

Posted: Published on September 17th, 2012

By Irene Maher, Times Staff Writer Irene MaherTampa Bay Times In Print: Monday, September 17, 2012 Regardless of your political leanings, at least one group of Americans was grateful for the Republican and Democratic National Conventions: Those affected by MS. People with multiple sclerosis appreciated the shout-out from Ann Romney, wife of presidential nominee Mitt Romney, at the Republican National Convention in Tampa and from first lady Michelle Obama with the Democrats a week later in Charlotte, N.C. Romney has been living with MS since 1998. Obama's father lived with the disease for about 30 years before his death at age 66. Both women related how their lives were affected by MS. That kind of exposure does more than increase awareness of an often misunderstood disease that afflicts 400,000 Americans, experts said. "In the case of Ann Romney, seeing someone at the podium, in the national spotlight, living an obviously busy, active life allows others to see how much you can accomplish with MS," said Dr. Stanley Krolczyk, director of the multiple sclerosis division in the department of neurology at USF Health. "It puts a different face on the disease when celebrities, like Montel Williams and Clay Walker, for example, … Continue reading

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MS patients, doctors appreciate attention to disease — no matter who gives it

Posted: Published on September 17th, 2012

By Irene Maher, Times Staff Writer Irene MaherTampa Bay Times In Print: Monday, September 17, 2012 Regardless of your political leanings, at least one group of Americans was grateful for the Republican and Democratic National Conventions: Those affected by MS. People with multiple sclerosis appreciated the shout-out from Ann Romney, wife of presidential nominee Mitt Romney, at the Republican National Convention in Tampa and from first lady Michelle Obama with the Democrats a week later in Charlotte, N.C. Romney has been living with MS since 1998. Obama's father lived with the disease for about 30 years before his death at age 66. Both women related how their lives were affected by MS. That kind of exposure does more than increase awareness of an often misunderstood disease that afflicts 400,000 Americans, experts said. "In the case of Ann Romney, seeing someone at the podium, in the national spotlight, living an obviously busy, active life allows others to see how much you can accomplish with MS," said Dr. Stanley Krolczyk, director of the multiple sclerosis division in the department of neurology at USF Health. "It puts a different face on the disease when celebrities, like Montel Williams and Clay Walker, for example, … Continue reading

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'Three-parent baby' fertility technique could be made legal

Posted: Published on September 17th, 2012

Should Mr Hunt decide to give the treatment the green light the technique could be written into law as early as next year, making Britain the first country in the world to allow human trials. Lisa Jardine, chair of the Human Fertilisation and Embryology Authority (HFEA), which is conducting the consultation, said the issue was of "enormous public interest", and not just to affected families. She said: "We find ourselves in unchartered territory, balancing the desire to help families have healthy children with the possible impact on the children themselves and wider society." Comparing the ethical debate with the birth of Louise Brown, the first IVF baby, in 1978, she added that many people had expected the child to be a "monster" and seen conception outside the womb as "absolutely appalling", but that IVF has since become commonplace. She said: "Here, we are going that mile further which is a genetic modification of the egg. That is uncharted territory. I feel very strongly that once we have genetic modification we have to be damn sure that we are happy, because this is not about us. "This is not about our children. It's not even about our grandchildren. It's about many … Continue reading

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Male Menopause, Testosterone, Prostate Cancer; The Connection Between Them

Posted: Published on September 17th, 2012

NEW YORK, Sept. 17, 2012 /PRNewswire/ --While there is some skepticism about male menopause there is no question that age-related changes in men impact testosterone level. Between pharmaceutical marketing and our sometimes-carefree trust in prescription medicine, a drastically climbing number of men are turning to androgen therapy for prostate cancer. Prostate cancer treatment expert and leading robotic prostatectomy SMART surgeon, Dr. David Samadi, urges men and their physicians to use hormone replacement therapy (HRT) with caution. (Photo: http://photos.prnewswire.com/prnh/20120917/NY75460 ) "Increased risk of prostate cancer is a very possible long-term side effect of testosterone replacement therapy," he says. "It concerns me that young men in their mid-30s or early-40s may count on testosterone for a boost in energy or sexual prowess and get much more than they bargained for in the long run." Dr. Samadi refers to the link between testosterone and prostate cancer risk. Male menopause, or andropause, symptoms occur much more gradually than menopause symptoms in women. Around age 35 or 40, a man's testosterone level naturally begins to decline at a rate of about 1-2% per year, making the term "pause" not entirely accurate. Normal testosterone level, at any age, is measured in a range of 300 to … Continue reading

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MEP fights European proposal to restrict stem cell research

Posted: Published on September 17th, 2012

Andrew Duff, MEP Proposals to restrict stem cell research have been opposed by a Cambridge-based MEP. Liberal Democrat Andrew Duff voted against a report in the European Parliament which he said would result in stricter requirements on voluntary and unpaid donations of tissues and cells for medical research. Afterwards, he said: The report swings the debate on stem cell research in the wrong direction, allowing individual EU member states to stop important medical science in its tracks. It is unhelpful to call for further restrictions on the donation of tissues and cells in the EU at a time when the number of patients in need of treatment based on stem cells is growing exponentially. The report was drawn up by a Conservative MEP. Mr Duff added: Cambridge is a world leader on life sciences. The European Parliaments restrictive conservative philosophy usually driven by ill-judged ethical motives puts our research centres at risk and could drive away high quality science abroad, for example to India. Regenerative medicine relies on a steady supply of stem cells. More: MEP fights European proposal to restrict stem cell research … Continue reading

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DNA Blueprint Maps How A Heart Becomes A Heart

Posted: Published on September 17th, 2012

Featured Article Academic Journal Main Category: Genetics Also Included In: Heart Disease;Stem Cell Research Article Date: 17 Sep 2012 - 4:00 PDT Current ratings for: DNA Blueprint Maps How A Heart Becomes A Heart 3.8 (5 votes) 2.33 (3 votes) The researchers write about their work in the 13 September online issue of Cell. The findings bring hope of new treatments for people born with life-threatening heart defects like irregular heart beat (arrhythmia) and hole in the heart (ventricular septal defect). Senior investigator Benoit Bruneau, associate director of cardiovascular research at Gladstone, an independent, nonprofit biomedical research group, tells the press in a statement: "Congenital heart defects are the most common type of birth defects -- affecting more than 35,000 newborn babies in the United States each year." "But how these defects develop at the genetic level has been difficult to pinpoint because research has focused on a small set of genes. Here, we approach heart formation with a wide-angle lens by looking at the entirety of the genetic material that gives heart cells their unique identity," he explains. For this part of the experiment they extracted DNA from developing and mature heart cells, because they contain the epigenetic signatures … Continue reading

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RBCC Expands Cell Culturing Focus to Include Adult Stem Cells

Posted: Published on September 17th, 2012

NOKOMIS, Fla.--(BUSINESS WIRE)-- Rainbow Biosciences, the biotechnology subsidiary of Rainbow Coral Corp. (RBCC), announced today that it will expand its focus on technology capable of culturing 3D cell clusters to include adult stem cells, as well. According to a report published last year by analysts as GIA, global investments in adult stem-cell research are forecast to reach $2.4 billion by 2015. That growth is being driven by technological advancements, the rising number of research groups engaged in stem cell research activities, broadening research activities and substantial investments from governments in leading global markets. A rising incidence of life-threatening diseases, un-met needs in the area of medicine, and costs associated with drug development also contribute to the market expansion. RBCC aims to help develop and market advanced new technologies capable of growing adult stem cells for research that more closely resemble those found in the body, said RBCC CEO Patrick Brown. Demand from the worlds growing elderly population is making continued stem-cell research a necessity, and we intend to position our company and our shareholders to capitalize on that need by providing the best stem-cell technology in the world. RBCC plans to develop technology to compete in the stem-cell research industry … Continue reading

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EMD Millipore Obtains Global Licensing Agreement for induced Pluripotent Stem(iPS) Cell Patent Technology with iPS …

Posted: Published on September 17th, 2012

BILLERICA, Mass.--(BUSINESS WIRE)-- EMD Millipore, the Life Science division of Merck KGaA of Darmstadt, Germany, and iPS Academia Japan, Inc. (Kyoto, Japan) today announced a global licensing agreement for AJs induced pluripotent stem (iPS) cell patent portfolio. The non-exclusive agreement provides EMD Millipore the opportunity to continue to develop and ultimately commercialize iPS cells for research applications. Under the agreement, EMD Millipore will continue to offer its STEMCCA reprogramming kits, which provide a highly efficient, reproducible method for creating iPS cells. The iPS cell patent portfolio is a result of work by Professor Shinya Yamanaka, MD, PhD, Center for iPS Cell Research and Application at Kyoto University, Japan. Terms of the agreement are not disclosed. We are extremely honored to collaborate with AJ on furthering research in the area iPS cell technology, said John Sweeney, Head, Bioscience Business Unit, EMD Millipore.To collaborate with the founder of iPS cell discovery provides the ideal opportunity for EMD Millipore to build upon our current product offering of the STEMCCA reprogramming kits, as well as further advance our research and discovery in the area of stem cell technology, and to provide our customers with the tools necessary in this important, breakthrough area of stem … Continue reading

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Court: Gov't can fund embryonic stem cell research – Boston.com

Posted: Published on September 17th, 2012

WASHINGTON (AP) A federal appeals court on Friday refused to order the Obama administration to stop funding embryonic stem cell research, despite complaints the work relies on destroyed human embryos. The U.S. Circuit Court of Appeals for the District of Columbia upheld a lower court decision throwing out a lawsuit that challenged federal funding for the research, which is used in pursuit of cures to deadly diseases. Opponents claimed the National Institutes of Health was violating the 1996 Dickey-Wicker law that prohibits taxpayer financing for work that harms an embryo. But a three-judge appeals court panel unanimously agreed with a lower court judges dismissal of the case. This is the second time the appeals court has said that the challenged federal funding of embryonic stem cell research was permissible. Dickey-Wicker permits federal funding of research projects that utilize already-derived ESCs which are not themselves embryos because no human embryo or embryos are destroyed in such projects, Chief Judge David B. Sentelle said in the ruling, adding that the plaintiffs made the same argument the last the time the court reviewed the issue. Therefore, unless they have established some extraordinary circumstance, the law of the case is established and we will … Continue reading

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