ScienceDaily (Sep. 10, 2012) Scientists at Mount Sinai School of Medicine have discovered a subpopulation of cells that display cancer stem cell properties and resistance to chemotherapy, and participate in tumor progression. This breakthrough could lead to the development of new tests for early cancer diagnosis, prognostic tests, and innovative therapeutic strategies, as reported in Cancer Cell. Resistance to chemotherapy is a frequent and devastating phenomenon that occurs in cancer patients during certain treatments. Unfortunately, tumors that initially respond to chemotherapy eventually become resistant to it, contributing to tumor progression and death. The study reveals that these new cancer "stem" cells, which have not been differentiated into more specific cell types, are capable of multiplying despite being exposed to chemotherapy, while differentiated cells die. Led by Carlos Cordon-Cardo, MD, PhD, Chair of Pathology, and Josep Domingo-Domenech, MD, PhD, Assistant Professor of Pathology at Mount Sinai, the research team generated cellular models of drug resistance by treating prostate tumor cell lines with increasing doses of the common chemotherapy drugs, including docetaxel. They identified a cell population expressing markers of embryonic development. In addition, these cells displayed cancer stem cell functions, including the capacity to initiate tumor cell growth. Next, the team … Continue reading →

By Julie S. Alipala Inquirer Mindanao ZAMBOANGA CITYKabang, the female Aspin dog who lost her upper snout when hit by a motorcycle while saving the lives of two girls, will be staying in Manila for two weeks for a stem cell treatment before further surgery in the United States. Veterinarian Anton Lim said the stem cell treatment will boost the dogs immunity before she is flown to the US within the month. Kabang was flown to Manila on Sunday morning. Lim said they were able to raise at least $10,000 from donations to shoulder expenses for Kabangs surgery on a protruding bone on her face. We are halfway there. As I have said, we need around $20,000, he said. Team Kabang is really grateful for the global effort as we received donations from almost a dozen countries, he added. The Animal Welfare Coalition of the Philippines has also helped provide medicines for Kabang. Follow Us Recent Stories: Tags: Animal Welfare Coalition of the Philippines , Aspin dog , Kabang , stem cell treatment , surgery Factual errors? Contact the Philippine Daily Inquirer's day desk. Believe this article violates journalistic ethics? Contact the Inquirer's Reader's Advocate. Or write The Readers' Advocate: … Continue reading →

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TAMPA, Fla.--(BUSINESS WIRE)-- Florida Hospital Tampa and Dr. James E. Lefler are the first in the Tampa Bay area to adopt the new FDA approved device called the Trevo Pro Clot Retriever manufactured by Stryker. The Trevo Pro is the next generation in clot removal technology. This powerful new tool literally retrieves blood clots from within the brains vasculature restoring blood flow to the brain faster for patients suffering from acute ischemic stroke, where blood flow is blocked. This new device has the ability to significantly improve patient outcomes. Trevo Pro is used to perform what is called a mechanical thrombectomy, also known as clot removal, said James E. Lefler, MD, co-director of the stroke program and neurointerventional radiologist at Florida Hospital Tampa. The Trevo Pro entraps the clot in a way that can immediately allow blood to start flowing back to the brain. This new device is 92% effective, advancing our ability and leading patients to better outcomes. We now have four different devices to treat stroke patients, depending on the type and location of stroke. The Trevo Pro becomes a fourth option; our other devices include the Concentric Merci Retrieval System, The Penumbra System and Solitaire Stroke Device. … Continue reading →